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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Mites --- thrips --- plant responses --- Defense

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Insect --- Immune responses --- Modulation --- Interaction --- pest

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Inflammation Pharmacology --- Pharmacology --- Inflammation --- inflammatory responses --- leukocyte --- anti-inflammatory agents

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This contributed volume covers a comprehensive account of the sources, toxic biological as well as environmental impacts, and possible remediation strategies for contamination by heavy metals. In biological systems, toxic metals affect the integrity of cellular organelles and act as carcinogens causing chromosomal aberrations or as systemic toxicants leading to cardiovascular, neurobehavioral, and immunological disorders. In plants, they interfere with photosynthesis, fertility, metabolite, and chlorophyll synthesis. Toxicity induced by heavy metals involves mechanistic approaches that need to be understood properly. They cannot be degraded by biological or chemical means and thus can only be converted to less harmful forms. The conventional detection methods include biosensors, voltammetry, atomic absorption spectrometry, and inductively coupled plasma with atomic emission spectrometry. All such strategies for metal detection and mitigation strategies are covered in this title under one section. This book incorporates classical views along with modern scientific approaches to develop an understanding of the subject matter suitable for academicians, researchers, planners, policymakers, NGOs, and environmental consultancies and raise awareness on this concern. Topics representing diverse sections namely environmental impacts, biological effects, and methods used for detection and remediation have been included to address all possible contemporary issues on the topic in one concise volume.

Plant physiology. --- Stress (Physiology). --- Plants. --- Ecology. --- Plant Physiology. --- Plant Stress Responses. --- Heavy metals --- Environmental aspects. --- Toxicology.

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Schistosomiasis is a severe parasitic disease, endemic in 74 developing countries with up to 600 million people, including many children, infected and 800 million at risk of contracting the disease following infection with Schistosoma mansoni, S. haematobium or S. japonicum. Disease burden is estimated to exceed 70 million disability-adjusted life-years, and leads to remarkably high YLD (years lived with disability) rates. Even more importantly, people with schistosomiasis are highly susceptible to malaria, tuberculosis and hepatic and acquired immunodeficiency viruses. There is only one drug, praziquantel, currently available for treatment and it has high efficacy, low cost, and limited side effects. However, only 13% of the target population has received the drug, and those treated are at continuous risk of reinfection necessitating repeated drug administration and the emergence of drug resistant parasites is a constant threat. There currently is no vaccine. While the target of >40% protection has been achieved with some molecules such as excretory-secretory proteins including calpain, glyceraldehyde 3-phosphate dehydrogenase, and cysteine peptidases, very recent articles reiterate the findings published during the last 2 decades of the last century, contradicting the established data of the pioneers of schistosome biology. A consensus should be reached without delay, in order to propose collaborative independent experiments and proceed ahead to pre- and clinical trials with efficacious candidate vaccine molecules. The proposed plan aims to finally reach an objective and fruitful agreement , via inviting established and young researchers from the United States, Brazil, China, Australia, and Europe who are working with different vaccine antigens, adjuvants, and approaches for immunization against S. mansoni, S. haematobium, and S. japonicum. It is hoped that the forum will end with a very few candidate antigens and a consensus approach regarding target immune responses, thus leading to encouraging the World Health Organization and other international foundations to sponsor the development and implementation of the urgently required, yet still elusive, vaccine for preventing and eliminating the transmission of schistosomiasis.

Schistosomiasis --- Schistosoma mansoni --- Schistosoma haematobium --- Type 2 cytokines --- Vaccine --- Immune responses --- Schistosoma japonicum --- Vaccine candidates