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The major aim of this book is to de-mystify splenic pathology for non-specialist consultants and trainees in histopathology. The interpretation of pathological changes in the human spleen provides a significant challenge to the skills of even the most highly trained histopathologists. This comprehensive account of the most important and frequently encountered pathological conditions affecting the spleen is highly illustrated in colour throughout with numerous detailed macroscopic and microscopic specimens. Emphasis is placed upon the importance of adequate clinical information and technical preparation of splenectomy specimens in obtaining the best possible histopathological assessment of the tissue. A systematic, analytical approach to interpretation of pathological changes is used throughout the book. This should enable readers to feel confident in their assessment of significant processes within the spleen. This volume serves as an illustrated atlas, a bench manual, as a text, and as a source of reference, and will be an indispensable guide.

Spleen --- Hematopoietic system --- Lymphoid tissue --- Histopathology.

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Since their discovery in 1973 by Zanvil Cohn and Ralph Steinman (Nobel Prize in Physiology and Medicine, 2011), dendritic cells (DCs) continue to intrigue research scientists as their new markers, subpopulations and properties are being detected and the relevant literature is being doubled each year. This book combines the most comprehensive reviews of several critical aspects of DC biology and function written by a group of international experts in the field. The first section briefly discusses recent advances in DC subtypes, phenotypes, and functions in different diseases. The following sections look closely at DC phenotyping, DC-NK cell interplay, and roles of DC in bone loss and repair and parasitic infections. The final section on DC and cancer includes perspectives on DC vaccination based on modifications and therapeutic applications.

Dendritic cells. --- Follicular dendritic cells --- Interdigitating cells --- Antigen presenting cells --- Lymphoid tissue --- Life Sciences --- Immunology --- Genetics and Molecular Biology --- Biochemistry

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Plasma can be defined as the extracellular matrix of blood cells. Plasma components, their role in human health risk evaluation, and their functional and clinical analyses are covered in this book. Furthermore, physical plasma-ionized gas is one of the four fundamental states of matter. This homonym has begun to emerge because it can interact with living systems. The physical plasma biomedical applications are reviewed in drug delivery and wound healing medical applications. This approach revolutionizes the therapeutic approaches in medicine and may open up new concepts and clinical applications. The book is an essential source for researchers in the field and provides a platform for different professions.

Wound healing. --- Plasma cells. --- Plasmacytes --- Plasmocytes --- Connective tissue cells --- Immunocompetent cells --- Lymphoid tissue --- Healing of wounds --- Wound repair --- Healing --- Regeneration (Biology) --- Medicine --- Internal Medicine --- Health Sciences

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The spleen is an organ which has diverse functions including immunologic and hematologic. The Atlas of Spleen Pathology describes and selectively illustrates the normal and pathologic conditions that afflict the spleen. This extraordinary collection of high quality digital images will materially aid in continuing efforts to recognize, understand, and accurately interpret the gross and light microscopic findings in spleens.

Bone marrow -- Diseases. --- Histology, Pathological -- Atlases. --- Histology. --- Pathology -- Atlases. --- Lymphoid Tissue --- Tissues --- Lymphatic System --- Immune System --- Anatomy --- Hemic and Immune Systems --- Spleen --- Medicine --- Health & Biological Sciences --- Hematologic Diseases --- Pathology --- Diseases --- Medicine. --- Pathology. --- Medicine & Public Health. --- Disease (Pathology) --- Medical sciences --- Medicine, Preventive --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Physicians --- Hematopoietic system --- Lymphoid tissue

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The thymus has been a mysterious gland for centuries. The awareness of its role has been progressing, in particular during the second half of the twentieth century. The thymic pathology is related to several complex congenital, non-oncological, and oncological diseases. Many of these illnesses require a multidisciplinary approach thus involving several specialists: the surgeon, the neurologist, the anesthetist, and the pathologist. For example, myasthenia gravis—the most challenging disease deriving from a thymic trouble—requires an accurate and multimodal treatment. The oncologic pathology of the thymus is likewise complex, and involves also the oncologist and the radiotherapist. In cases of congenital thymic diseases, a transplantation of the thymus can be taken into consideration. This volume is an update on the pathology of this gland and includes 24 chapters written by international and well-known experts. The whole thymic pathology is described and new concepts about the nosological classification and the thymic neoplasm staging system are reported. Some chapters are focused on the radiologic, mini-invasive, and surgical diagnosis, and other chapters deal with surgical and non-surgical treatments. Special chapters are devoted to myasthenia gravis and thymus transplantation. The book will appeal to all the specialists involved in the treatment of thymic pathology, but can also be of interest to practitioners, and undergraduate and graduate students. .

Medicine & Public Health. --- Thoracic Surgery. --- Surgery. --- Pediatrics. --- Oncology. --- Neurology. --- Medicine. --- Thoracic surgery. --- Médecine --- Neurologie --- Cancérologie --- Pédiatrie --- Chirurgie --- Lymphatic Diseases. --- Thymus -- Diseases. --- Thymus Gland. --- Thymus Gland --- Lymphatic Diseases --- Lymphoid Tissue --- Hemic and Lymphatic Diseases --- Diseases --- Lymphatic System --- Tissues --- Anatomy --- Immune System --- Hemic and Immune Systems --- Clinical Endocrinology --- Surgery - General and By Type --- Medicine --- Surgery & Anesthesiology --- Health & Biological Sciences --- Thymus --- Thymus. --- Diseases. --- Thymus gland --- Endocrine glands --- Lymphoid tissue --- Oncology  . --- Nervous system --- Neuropsychiatry --- Tumors --- Paediatrics --- Pediatric medicine --- Children --- Surgery, Primitive --- Thoracic surgery --- Thoracic surgeons --- Health and hygiene --- Neurology .