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The aim of this open access book is to provide a unique, timely, critical and comprehensive compilation of more than 30 years of robust international experimental and clinical research related to the basic science and therapeutic application of water-filtered infrared-A (wIRA) and hyperthermia in oncology, psychiatry (depression), musculoskeletal disorders, dermatology, infectiology, and surgery. This is an internationally absolutely unique attempt which publication is timely and of great interest in medical as well as in natural sciences. The aim is to enhance communication and advance the use of heat therapy for patient benefit, and to generate an environment in which anyone with an interest in hyperthermia can discuss, collaborate, network, and share events and resources. Productive dialogue and discussion among scientists and practitioners on issues relating to hyperthermia therapy is essential, especially relating to thermal transmission by water-filtered infrared-A (wIRA). The specificity and advantage of this technology is its tolerance by tissue, and its penetration of up to 3 cm allows the delivery of high heat dosages that are relevant across multiple clinical indications. Currently, wIRA is being applied in Austria, Germany, Portugal, Switzerland, The Netherlands, UK and the USA. The authors’ hope is that its use will increase in these countries, and also expand into others. This book will be an invaluable tool for oncologists, surgeons, dermatologists as well as physiotherapists.
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Thermotherapy --- Heat --- Thermothérapie --- Chaleur --- Periodicals --- Physiological effect --- Périodiques --- Effets physiologiques --- Hyperthermia, Induced. --- Thermotherapy. --- HYPERTHERMIA --- Health Sciences --- Clinical Medicine --- Medical Education, Training & Research --- Oncology --- INDUCED --- periodicals --- Health Sciences. --- Oncology. --- periodicals. --- Hyperthermia, Induced --- Hyperthermia. --- Heat therapy --- Hot-air treatment --- Induced hyperthermia --- Induced Hyperthermia --- Therapeutic Hyperthermia --- Therapy, Fever --- Fever Therapy --- Hyperthermia, Local --- Hyperthermia, Therapeutic --- Local Hyperthermia --- Therapeutic use --- Physical therapy --- Hyperthermic Intraperitoneal Chemotherapy --- Chemotherapy, Hyperthermic Intraperitoneal --- Hyperthermic Intraperitoneal Chemotherapies --- Intraperitoneal Chemotherapy, Hyperthermic --- Fever --- Hot Temperature --- hyperthermia --- thermal therapy --- heat treatment --- thermal response --- thermal energy treatment systems --- Oncology. Neoplasms --- Human medicine --- Hyperthermia
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Public health --- Epidemics --- Fever. --- Hyperthermia --- Pyrexia --- Body temperature --- Exanthemata --- History.
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This book describes the tools, developed by the author, for perturbing endogenous mechano-sensitive ion channels for magneto-mechanical neuro-modulation. He explores the ways in which these tools compare against existing ones such as electricity, chemicals, optogenetics, and techniques like thermos/magneto-genetics. The author also reports on two platforms—magnetic ratcheting and magnetic microfluidics for directed evolution and high throughput culture of magnetotactic bacteria—that produce high quality magnetic nanoparticles for biomedical applications like neural stimulations. This thesis was submitted to and approved by the University of California, Los Angeles. Introduces technology for non-invasive control of neural activities that offer deep tissue penetration and controllable dosage; Examines the effects of biomechanical forces on cellular functions; Explores how to improve the reproducibility and uptake of magnetic tools for non-invasive neural modulation.
Engineering. --- Nanoscale science. --- Nanoscience. --- Nanostructures. --- Biomedical engineering. --- Nanotechnology. --- Biomedical Engineering. --- Nanoscale Science and Technology. --- Neural stimulation. --- Magnetic nanoparticle hyperthermia. --- Hyperthermia, Magnetic fluid --- Hyperthermia, Magnetic nanoparticle --- Hyperthermia, Magnetic nanoparticle-based --- Magnetic fluid hyperthermia --- Magnetic nanoparticle-based hyperthermia --- MNH (Magnetic nanoparticle hyperthermia) --- Thermotherapy --- Nerve stimulation --- Stimulation, Neural --- Electric stimulation --- Electrodiagnosis --- Electrophysiology --- Electrotherapeutics --- Biomedical Engineering and Bioengineering. --- Molecular technology --- Nanoscale technology --- High technology --- Clinical engineering --- Medical engineering --- Bioengineering --- Biophysics --- Engineering --- Medicine --- Nanoscience --- Physics --- Nano science --- Nanoscale science --- Nanosciences --- Science
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The book "Hyperthermia", published by InTech, and edited by Dr. Nagraj Huilgol, of the Department of Radiation Oncology, Dr. Balabhai Nanavati Hospital, India, is comprised of 8 Open Access chapters, covering a wide range of Hyperthermia-related scientific research.
Thermotherapy. --- Heat --- Fever. --- Physiological effect. --- Heat therapy --- Hot-air treatment --- Hyperthermia, Induced --- Induced hyperthermia --- Physical therapy --- Hyperthermia --- Pyrexia --- Body temperature --- Exanthemata --- Heat stress (Biology) --- High temperatures --- Therapeutic use --- Physiological effect --- Accident & emergency medicine
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In Silico Approach Towards Magnetic Fluid Hyperthermia in Cancer Treatment: Modeling and Simulation presents mathematical modeling and simulation approaches contrary to costly and time consuming in-vivo and in-vitro studies. Finite element method-based models of all hyperthermia processes of liver, brain and breast tumors are simulated on COMSOL Multiphysics software. Problems of constant versus variable heat sources, the backflow problem, the enhanced permeation and retention effect, the flow around Happel's sphere in cells model structure, the deformation effect in poroelastic brain tumor, 3D flow through porous tissue, the reacting nanofluid flows, and optimization of parameters have been simulated for quantitative analysis. This important reference aids in hyperthermia treatment planning in clinical applications and provides an important compendium for practitioners as well as non-medical practicing scientists and engineers and is resource for both research and medical practice in hyperthermia treatment planning in clinical applications. Includes the diversities of cancer treatment modalities for their eradication with minimum damage to surrounding normal tissue Addresses tumors of different organs including liver, brain and breast Deals with mathematical modeling and simulation approaches contrary to costly and time consuming in-vivo and in-vitro studies Provides insights on how to use hyperthermia in cancer treatments in addition to other conventional types of treatments.
Cancer --- Thermotherapy. --- Heat therapy --- Heat --- Physiological effect. --- Heat stress (Biology) --- High temperatures --- Hyperthermia --- Physiological effect --- Computer Simulation --- Models, Theoretical --- Hyperthermia, Induced --- Neoplasms --- Thermotherapy --- Mathematical models.
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Heat --- Physiological effect. --- Heat stress (Biology) --- High temperatures --- Hyperthermia --- Physiological effect --- Calor --- Fisiologia humana
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"Febrile seizures are the most common seizures in infants and children worldwide, This fact provides strong impetus to study and understand them and their consequences, and consider their treatment. These topics were the focus of the first edition of this book. The 20 years since the publication of this first edition have witnessed an explosion of new information about febrile seizures, meriting this new edition. Key advances have been made in the genetics and neurobiological underpinnings of febrile seizures and especially the very long fever-related seizures called febrile status epilepticus. The role of neuroinflammatory factors in the emergence of these seizures and their consequences, the demonstration of unique clinical and neuroradiological aspects of febrile status epilepticus, and the prospect of predictive (bio)markers to identify and characterize cognitive and epilepsy outcomes are exciting and important. In this edition, the authors and editors tackle these developments in chapters addressing the questions of parents, physicians, allied health care professionals and basic and translational scientists."--
Fever --- Treatment. --- Immunological aspects. --- Hyperthermia --- Pyrexia --- Body temperature --- Exanthemata --- Febrile convulsions. --- Seizures, Febrile --- Status Epilepticus
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Cancer --- Thermotherapy. --- Hyperthermia, Induced. --- Caspases --- Neoplasms --- Molecular Targeted Therapy. --- therapeutic use. --- therapy.
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The road of acceptance of oncologic thermotherapy/hyperthermia as a synergistic modality in combination with standard oncologic therapies is still bumpy. This is partially due to the lack of level I evidence from international, multicentric, randomized clinical trials including large patient numbers and a long term follow-up. Therefore we need more level I EVIDENCE from clinical trials, we need HARMONISATION and global acceptance for existing technologies and a common language understood by all stakeholders and we need INNOVATION in the fields of biology, clinics and technology to move thermotherapy/hyperthermia forward. This is the main focus of this reprint. In this reprintyou find carefully selected and peer-reviewed contributions from Africa, America, Asia, and Europe. The published papers from leading scientists from all over the world covering a broad range of timely research topics might also help to strengthen thermotherapy on a global level.
perfusion estimation --- temperature monitoring --- conductivity reconstruction --- systems medicine --- immune system in silico --- perceptron --- antigen pattern --- danger signal --- fractionation --- immune response --- head and neck cancer --- hyperthermia --- reirradiation --- treatment outcome --- hyperthermia treatment planning --- adaptive planning --- temperature optimization --- low-middle-income group countries --- cancer --- radiotherapy --- chemotherapy --- recurrent breast cancers --- cervical cancer --- head and neck cancers --- cost-effective --- meta-analysis --- intensity-modulated radiotherapy --- prostate cancer --- thermal dose --- thermometric parameters --- preclinical data --- clinical evidence --- modulated electro-hyperthermia --- abscopal effect --- locally advanced cervical cancer --- resource-constrained setting --- radiosensitiser --- rectal cancer --- chemoradiotherapy --- tumour control --- loco-regional hyperthermia --- oncology --- cellular selection --- bioelectromagnetics --- complexity --- immune-effects --- moderate hyperthermia --- deep hyperthermia --- radiative hyperthermia --- patterns of care --- reimbursement --- regional hyperthermia --- neoadjuvant chemoradiation --- survival --- induced --- brachytherapy --- prostatic neoplasms --- interstitial hyperthermia --- treatment plan optimization --- prostate --- thermoradiotherapy --- linear quadratic model --- biological modeling --- thermal dosimetry --- hypoxia --- radiation therapy --- reoxygenation --- perfusion --- oxygen consumption rate --- local tumor control --- biomarker --- immune phenotype --- hyperthermia treatment sequence --- breast cancer --- immune checkpoint molecules --- dendritic cell activation --- n/a
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