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This book is essential reading for medical or veterinary practitioners who need to understand the new fluid physiology and to apply it to the safe care of patients. The Starling principle is one of medicine's most important concepts and originates from Ernest Starling's laboratory research 120 years ago. However, inappropriate fluid therapy is now recognised as harming and even killing thousands of patients every year. In 2004, a landmark study was published which confirmed the hypotheses put forward by Sheldon Weinbaum and Charles Michel, among other physiologists, that, in most tissues and in most situations, capillaries filter fluid to the interstitium, but do not reabsorb it. This book draws together for the first time the evolving science of the steady-state Starling principle and the clinical evidence that reveals its applicability to safer patient care. It is a thorough re-appraisal of the basics of fluid therapy. The mantra of colloid boluses for plasma volume resuscitation and colloid-free isotonic salt solution for extracellular fluid volume does not explain observations from blinded clinical trials, and the expectation of benefit for resuscitation with colloids, particularly in respect of oedema, has not materialised. Now that there is consensus that colloid volume therapy should not be used in critically-ill patients, there is a pressing need for a new paradigm for fluid therapy. This book proposes an improved paradigm that takes into consideration the Starling principle, which has been neglected by clinicians and revised by physiologists in recent years. It retires the view of colloids as preferred plasma substitutes, and focuses instead on the central volume of distribution of an infused fluid, its rate of distribution to a peripheral volume, and its rate of excretion. In short, it emphasises volume kinetics.

Fluid therapy. --- Colloids --- Plasma exchange (Therapeutics) --- Therapeutic use.

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Animal Diseases --- Drug Therapy --- Diseases --- Therapeutics --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Dog Diseases --- Cat Diseases --- Fluid Therapy --- Animal Diseases. --- Drug Therapy. --- Disease. --- Therapeutics. --- Dog Diseases. --- Cat Diseases. --- Fluid Therapy.

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During the past few decades, high-profile cases like that of Terry Schiavo have fueled the public debate over forgoing or withdrawing artificial nutrition and hydration from patients in a persistent vegetative state (PVS). These cases, whether involving adults or young children, have forced many to begin thinking in a measured and careful way about the moral legitimacy of allowing patients to die. Can families forgo or withdraw artificial hydration and nutrition from their loved ones when no hope of recovery seems possible?Many Catholics know that Catholic moral theology has formulated a well-

Religion and Medicine. --- Persistent Vegetative State --- Fluid Therapy --- Enteral Nutrition --- Catholicism. --- Euthanasia, Passive --- Euthanasia --- Artificial feeding. --- Fluid therapy --- Loss of consciousness. --- Persistent vegetative state --- Medical ethics. --- Fluid replacement therapy --- Fluids --- Therapeutics --- Water-electrolyte balance (Physiology) --- Blackouts (Loss of consciousness) --- Consciousness, Loss of --- Insensibility --- Unconscious state --- Unconsciousness --- Neurologic manifestations of general diseases --- Biomedical ethics --- Clinical ethics --- Ethics, Medical --- Health care ethics --- Medical care --- Medicine --- Bioethics --- Professional ethics --- Nursing ethics --- Social medicine --- Minimally conscious state --- Permanent vegetative state --- Persistent unawareness state --- Post-traumatic vegetative state --- Posttraumatic vegetative state --- PVS (Persistent vegetative state) --- Unawareness state, Persistent --- Vegetative state, Persistent --- Brain damage --- Loss of consciousness --- Coma --- Artificial nutrition --- Feeding, Artificial --- Nutrition --- Roman Catholic Ethics --- Roman Catholicism --- Roman Catholics --- Catholic, Roman --- Catholicism, Roman --- Catholics, Roman --- Ethic, Roman Catholic --- Ethics, Roman Catholic --- Roman Catholic --- Roman Catholic Ethic --- Medicine and Religion --- Parish Nursing --- therapy. --- ethics. --- Moral and ethical aspects. --- Religious aspects --- Catholic Church. --- Therapeutic use --- Moral and ethical aspects --- Patients --- Religious aspects. --- Health Workforce --- Comatose state

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Water-electrolyte imbalances. --- Acid-base imbalances. --- Water-electrolyte imbalances --- Acid-base imbalances --- Water-Electrolyte Imbalance --- Acid-Base Imbalance --- Potassium --- physiopathology. --- diagnosis. --- metabolism. --- physiopathology --- diagnosis --- metabolism --- Water-electrolyte balance (Physiology) --- Acid-base equilibrium --- Kalium --- Alkali metals --- High-potassium diet --- Low-potassium diet --- Acid-base disorders --- Acid-base imbalance --- Imbalances, Acid-base --- Body fluid disorders --- Electrolyte disorders --- Electrolyte-water imbalances --- Imbalances, Water-electrolyte --- Water-electrolyte imbalance --- Electrolyte-water balance (Physiology) --- Fluid-electrolyte balance (Physiology) --- Water balance (Physiology) --- Homeostasis --- Aquaporins --- Fluid therapy --- Osmoregulation --- Potassium.

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Fluid, Electrolyte and Acid-Base Disorders: Clinical Evaluation & Management  is a clear and concise presentation of the fundamentals of fluid, electrolyte and acid-base disorders frequently encountered in clinical practice.   Each chapter begins with pertinent basic physiology followed by its clinical disorder. Cases for each fluid, electrolyte and acid-base disorder are discussed with answers.  In addition, board-type questions with explanations are provided for each clinical disorder to increase the knowledge for the clinician. Practical and clinically oriented, this book is a handy reference for practicing physicians, students, residents and fellows.

Fluid therapy. --- Veterinary medicine. --- Water-electrolyte imbalances. --- Electrolyte disorders --- Electrolyte-water imbalances --- Imbalances, Water-electrolyte --- Water-electrolyte imbalance --- Farriery --- Large animal medicine --- Large animal veterinary medicine --- Livestock medicine --- Veterinary science --- Fluid replacement therapy --- Fluids --- Therapeutic use --- Medicine. --- Critical care medicine. --- Internal medicine. --- Nephrology. --- Medicine & Public Health. --- Internal Medicine. --- Intensive / Critical Care Medicine. --- Body fluid disorders --- Medicine --- Animal health --- Animals --- Domestic animals --- Livestock --- Therapeutics --- Water-electrolyte balance (Physiology) --- Diseases --- Losses --- Intensive care --- Intensive medicine --- Emergency medicine --- Intensive care units --- Medicine, Internal --- Internal medicine --- Kidneys