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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Proteinopathy --- Dementia --- neurodegenerative disease --- Brain aging --- protein aggregates

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

brain aging --- Alzheimer’s disease --- metabolic neuroimaging biomarkers --- vascular neuroimaging biomarkers

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This book offers practitioners a hands-on guide to bedrock clinical tasks. The first half of the volume addresses special considerations for conducting neuropsychological assessments of older adults, such as disease management issues, sleep concerns, and ethical matters. The second section illuminates symptoms and issues associated with specific disorders and their relationship to functional impairments. Information is presented in a practitioner friendly format with sample cases, test battery recommendations, and “clinical pearls” from recognized experts in the field. Among the Handbook’s topics:  ·                   Serial assessments in dementia. ·                   Considerations for neuropsychological evaluations with older minority patients. ·                   Impact of medications on cognition. ·                   Assessing depression and anxiety in older adults. ·                   Prevention of cognitive decline. ·                   Plus in-depth chapters on late-life cognitive impairment resulting from Alzheimer’s disease, vascular cognitive impairment, cancer, stroke, epilepsy, and a variety of other conditions.  Useful and informative well beyond its immediate specialty, the Handbook on the Neuropsychology of Aging and Dementia is a practical reference for neuropsychologists, neurologists, primary care physicians (geriatricians, internists, family doctors), health psychologists, clinical psychologists, and clinical social workers.

Brain -- Aging -- Handbooks, manuals, etc. --- Dementia -- Handbooks, manuals, etc. --- Neurobehavioral Manifestations. --- Neuropsychiatry. --- Neuropsychology -- methods. --- Neuropsychology. --- Older people -- Mental health -- Handbooks, manuals, etc. --- Brain --- Dementia --- Older people --- Psychiatry and Psychology --- Adult --- Delirium, Dementia, Amnestic, Cognitive Disorders --- Brain Diseases --- Age Groups --- Central Nervous System Diseases --- Persons --- Nervous System Diseases --- Named Groups --- Diseases --- Cognition Disorders --- Mental Disorders --- Aged --- Human Anatomy & Physiology --- Health & Biological Sciences --- Neuroscience --- Aging --- Mental health --- Neuropsychology --- Psychological aspects --- Aphrenia --- Aphronesia --- Athymia --- Dementias --- Age --- Ageing --- Senescence --- Physiological effect --- Psychology. --- Geriatrics. --- Neurology. --- Geriatrics/Gerontology. --- Neurophysiology --- Psychophysiology --- Neurobehavioral disorders --- Psychoses --- Developmental biology --- Gerontology --- Longevity --- Age factors in disease --- Psychology, clinical. --- Medicine --- Nervous system --- Neuropsychiatry --- Health and hygiene --- Neurology .

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The increased life expectancy seen in the past century constitutes an unprecedented economic challenge to modern societies.  Public health perspectives aside, people do not want to simply live longer; they want to age successfully and remain physically and mentally active in their later years.  Major advances in our understanding of brain aging and, in particular, the distinction between normal and pathological aging are required before this goal is realized.  This volume discusses the current state of research findings related to healthy brain aging by integrating human clinical studies and translational research in animal models.  Several chapters offer a unique overview of successful aging, age-related cognitive decline and its associated structural and functional brain changes, as well as how these changes are influenced by reproductive aging.  Insights provided by preclinical studies in mouse models and advanced neuroimaging techniques in humans are also presented.  Another series of chapters specifically discuss the distinction between normal aging and Mild Cognitive Impairment, a frequent precursor of dementia, the recent advances made through both epidemiological and neuroimaging studies, and the research challenges to be addressed before we can accurately predict progression to dementia among those older adults who are at risk.  The book also covers medical and psychiatric conditions, such as cerebrovascular diseases and depression, that can negatively impact cognition.  It closes with a presentation of strategies to diminish and delay age-related cognitive declines, both pharmacological and non-pharmacological.  This volume provides topics that will be useful to researchers, clinicians and students interested in the current knowledge and research challenges in neurobiological perspectives in aging as well as future research directions in aging research.

Aging -- Psychology. --- Brain -- Aging. --- Neurobiology. --- Aging --- Psychological Phenomena and Processes --- Behavioral Sciences --- Psychiatry and Psychology --- Biological Science Disciplines --- Adult --- Growth and Development --- Behavior --- Physiological Processes --- Natural Science Disciplines --- Age Groups --- Behavioral Disciplines and Activities --- Behavior and Behavior Mechanisms --- Physiological Phenomena --- Persons --- Disciplines and Occupations --- Named Groups --- Phenomena and Processes --- Mental Disorders --- Aged --- Physiology --- Behavioral Symptoms --- Psychology --- Mental Processes --- Medicine --- Social Welfare & Social Work --- Health & Biological Sciences --- Social Sciences --- Gerontology --- Neurology --- Brain --- Animal behavior. --- Developmental biology. --- Aging. --- Development (Biology) --- Animals --- Animals, Habits and behavior of --- Behavior, Animal --- Ethology --- Medicine. --- Neurosciences. --- Geriatrics. --- Medical research. --- Behavioral sciences. --- Quality of life. --- Biomedicine. --- Behavioral Sciences. --- Geriatrics/Gerontology. --- Medicine/Public Health, general. --- Quality of Life Research. --- Developmental Biology. --- Biology --- Growth --- Ontogeny --- Animal psychology --- Zoology --- Ethologists --- Psychology, Comparative --- Neurosciences --- Quality of Life --- Research. --- Life, Quality of --- Economic history --- Human ecology --- Life --- Social history --- Basic needs --- Human comfort --- Social accounting --- Work-life balance --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Older people --- Neural sciences --- Neurological sciences --- Neuroscience --- Nervous system --- Diseases --- Health and hygiene --- Health Workforce --- Biomedical research --- Medical research