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The book centers on the treatment of pain using the appropriate opioid and a suitable co-medication whenever necessary. While many physicians or health care providers either subscribe or advocate analgesics in response to a painful situation, their basic knowledge when and how to apply them frequently is scarce. And often there is a lack of sufficient knowledge on their potential side-effects, their mode of action, 2+ their possible interactions with other agents such as ß-blockers, Ca -antagonists, ACE inhibitors and/or benzodiazepines. In addition, not all analgesics are equivalent or equally proficient at alleviating certain painful ailments. Although there have been many of articles and books written on the subject of effective pain treatment, very few have centered on the rational use of opioids. In fact opiophobia is still around with some caregivers who consider an opioid not to be the first-line drug in severe pain. On the contrary, the myth is still around that an opioid is potentially dangerous even when used in serious painful situations, and although the WHO has stated that opioids are elementary in therapeutic strategy taking into account that they are used by mouth, by the ladder, at fixed time intervals and advocating a time consistent release formulation, they are not available in every country.
Narcotics. --- Opioids --- Therapeutic use. --- Opium-like agents --- Analgesics --- Narcotics --- Opium --- Opiates --- Central nervous system depressants --- Anesthesiology. --- Critical care medicine. --- Emergency medicine. --- Oncology . --- Intensive / Critical Care Medicine. --- Emergency Services. --- Oncology. --- Intensive care --- Intensive medicine --- Medicine --- Emergency medicine --- Intensive care units --- Anaesthesiology --- Surgery --- Tumors --- Medicine, Emergency --- Critical care medicine --- Disaster medicine --- Medical emergencies --- Analgesics, Opioid --- Pain Management. --- Opioids. --- Pain --- Opioïdes --- Douleur --- therapeutic use. --- Treatment. --- Traitement --- EPUB-LIV-FT LIVMEDEC LIVSANTE SPRINGER-B
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This Brief takes the reader on a chemical journey by following the history for over two centuries of how an opiate became an opioid, thus spawning an empire and a series of crises. These imperfect resemblances of alkaloids are both natural and synthetic substances that, particularly in America, are continually part of a growing concern about overuse. This seemed an inviting prospect for those in pain, but as the ubiquitous media coverage continues to lay bare, the levels of abuse point to the fact that perhaps an epidemic is upon us, if not a culture war. Seeking answers to how and why this addiction crisis transpired over two hundred years of long development, this Brief examines the role that the chemistry laboratory played in turning patients into consumers. By utilizing a host of diverse sources, this Brief seeks to trace the design and the production of opioids and their antecedents over the past two centuries. From the isolation and development of the first alkaloids with morphine that relieved pain within the home and on the battlefield, to the widespread use of nostrums and the addiction crisis that ensued, to the dissemination of drugs by what became known as Big Pharma after the World Wars; and finally, to competition from home-made pharmaceuticals, the progenitor was always, in some form, a type of chemistry lab. At times, the laboratory pressed science to think deeply about society's maladies, such as curing disease and alleviating pain, in order to look for new opportunities in the name of progress. Despite the best intentions opioids have created a paradox of pain as they were manipulated by creating relief with synthetic precision and influencing a dystopian vision. Thus, influence came in many forms, from governments, from the medical community, and from the entrepreneurial aspirations of the general populace. For better, but mostly for worse, all played a role in changing forever the trajectory of what started with the isolation of a compound in Germany. Combining chemistry and history in a rousing new long-form narrative that even broadens the definition of a laboratory, the origins and future of this complicated topic are carefully examined.
Chemistry. --- Pharmacology. --- Organic chemistry. --- Chemistry --- Psychopharmacology. --- Medicine --- History of Chemistry. --- Organic Chemistry. --- History of Medicine. --- Pharmacology/Toxicology. --- History. --- Narcotics --- Drug addiction --- Overdose --- Addiction to drugs --- Drug dependence --- Drug dependency --- Drug habit --- Narcotic addiction --- Narcotic habit --- Narcotics addiction --- Drug abuse --- Opiates --- Central nervous system depressants --- Chemistry-History. --- Chemistry, Organic. --- Medicine. --- Toxicology. --- Behavioral pharmacology --- Drugs --- Chemotherapy --- Pharmacology --- Psychotropic drugs --- Chemicals --- Poisoning --- Poisons --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Organic chemistry --- Psychotropic effects --- Toxicology --- Health Workforce --- Chemistry—History. --- Medicine—History. --- Drug effects --- Medical pharmacology --- Pharmacy --- Physiological effect
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The Bulletin is a continuous publication since 1949, and provides information on developments in drug control at the local, national, regional, and international levels that can be of benefit to the international community.
Narcotics --- Narcotics. --- Drugs. --- NARCOTICOS --- Substance-Related Disorders. --- PUBLICACIONES PERIODICAS. --- Substance Addiction --- Drug Abuse --- Drug Addiction --- Drug Dependence --- Drug Habituation --- Drug Use Disorders --- Organic Mental Disorders, Substance-Induced --- Substance Abuse --- Substance Dependence --- Substance Use Disorders --- Abuse, Drug --- Abuse, Substance --- Abuses, Substance --- Addiction, Drug --- Addiction, Substance --- Dependence, Drug --- Dependence, Substance --- Disorder, Drug Use --- Disorder, Substance Use --- Drug Use Disorder --- Habituation, Drug --- Organic Mental Disorders, Substance Induced --- Substance Abuses --- Substance Use Disorder --- Narcotic --- Narcotic Effect --- Narcotic Effects --- Analgesics, Narcotic --- Narcotic Analgesics --- Effect, Narcotic --- Effects, Narcotic --- Opiates --- Central nervous system depressants --- Prescription Drug Abuse --- Abuse, Prescription Drug --- Drug Abuse, Prescription --- Drug and Narcotic Control --- Disruptive, Impulse Control, and Conduct Disorders --- Psychoses, Alcoholic --- Social Problems --- Street Drugs --- Designer Drugs --- Behavior, Addictive --- Codependency (Psychology) --- Alcohol-Related Disorders --- Prescription Drug Misuse --- Narcotic Abuse --- Narcotic Addiction --- Narcotic Dependence --- Abuse, Narcotic --- Addiction, Narcotic --- Dependence, Narcotic --- Substance-Related Disorders --- Illicit Drugs --- Codependency, Psychological --- Chemical Dependence --- Substance Use --- Chemical Dependences --- Dependence, Chemical --- Dependences, Chemical --- Substance Uses --- Use, Substance --- Narcotic-Related Disorders --- Substance Related Disorder --- Disorder, Substance Related --- Disorders, Substance Related --- Related Disorder, Substance --- Related Disorders, Substance --- Drogues --- Drogues. --- Toxicomanie. --- Annuaires. --- Stupéfiants.
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