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"An investigative reporter traces the role of DNA evidence in two groundbreaking murder cases involving young girls killed two decades apart in the same town. In 1977, the industrial town of Port Alberni was shaken by the brutal murder of twelve-year-old Carolyn Lee, who had been abducted while walking home from her dance class. In 1996, the town was devastated again when eleven-year-old Jessica States disappeared while chasing foul balls at a local fast-pitch game, her lifeless body later found beaten in the woods. At the time of States's murder, Shayne Morrow was working as a reporter for the Alberni Valley Times. His interest in forensic science led him to cover the States case and relate it back to the Lee case, which had gone unsolved for years. In his coverage, Morrow gained unprecedented access to the investigators and scientists who were on the trail of both killers. Emerging DNA technology in the mid-1990s led to a renewed interest in the Lee case and ultimately to the conviction of her killer, Gurmit Singh Dhillon, in 1998. The technological mechanisms put in place during that case would lay the groundwork for the capture of States's killer, Roderick Patten, a year later. The Bulldog and the Helix is a riveting portrait of a town rocked twice by the most heinous type of crime imaginable and a community's unrelenting search for justice."--
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DNA fingerprinting --- DNA fingerprinting. --- Forensic genetics --- Technique.
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In the field of forensics, there is a critical need for genetic tests that can function in a predictive or inferential sense, before suspects have been identified, and/or for crimes for which DNA evidence exists but eye-witnesses do not. Molecular Photofitting fills this need by describing the process of generating a physical description of an individual from the analysis of his or her DNA. The molecular photofitting process has been used to assist with the identification of remains and to guide criminal investigations toward certain individuals within the sphere of prior suspects.
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Forensic DNA Technology examines the legal and scientific issues relating to the implementation of DNA print technology in both the crime laboratory and the courtroom. Chapters have been written by many of the country's leading experts and trace the underlying theory and historical development of this technology, as well as the methodology utilized in the Restriction Fragment Length Polymorphism (RFLP) and Polymerase Chain Reaction (PCR) techniques. The effect of environmental contaminants on the evidence and the statistical analysis of population genetics data as it relates to the potential of this technology for individualizing the donor of the questioned sample are also addressed. Other topics include the proposed guidelines for using this technology in the crime laboratory, the perspective of the prosecution and the defense, the legal standards for determining the admissibility and weight of such evidence at trial. Finally, the issues of validation and the standards for interpretation of autoradiograms are brought into focus in a detailed study of actual case work. Forensic scientists, prosecuting attorneys, defense attorneys, libraries, and all scientists working with DNA technology should consider this a "must have" book.
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"Th[is] book maps the ways to the analysis of the genome of Gregor Johann Mendel, a project which was carried out to mark the 200th anniversary of the birth of this important scientist. It describes the exhumation of his remains from the Augustinian tomb at the Central Cemetery in Brno and the scientific examination that followed, as well as the search for traces of Mendel's DNA on his personal belongings kept in the Augustinian Abbey in Old Brno. The individual chapters, that is, the ways of research, introduce the reader to the initial impulses leading to the archaeological research on the tomb and the subsequent analysis of Mendel's genome. They describe the process of identifying the remains found in the grave with the person of Abbot Mendel, the anthropological research on his skeletal remains, as well as the process of isolation and analysis of the DNA of this historical figure. Rich photographic documentation chronicles the exciting work of the scientific team. Thanks to their efforts, the book reveals surprising findings and new, important details about the founder of genetics."--Page 4 of cover.
Human remains (Archaeology) --- DNA fingerprinting. --- Mendel, Gregor,
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Los análisis genéticos afectan a derechos fundamentales, por lo que el uso de esta información debe estar supeditado a vías de control democrático. En la actualidad, la lucha contra grandes delitos, como por ejemplo el terrorismo, aparentemente legitima a invadir derechos antes considerados intangibles. La presente obra, fruto del trabajo multidisciplinar llevado a cabo por juristas, filósofos, biólogos, técnicos y médicos, tiene por objetivo poner de manifiesto cuáles son los problemas ético-jurídicos derivados de la obtención, el análisis y el almacenamiento del ADN, así como sus usos judiciales y extrajudiciales. Ante el difícil equilibrio entre libertad individual y seguridad colectiva, este libro ayuda a comprender los conflictos que subyacen en el manejo de una herramienta informativa tan poderosa como son las muestras y los perfiles del ADN.
Ressenya genètica --- Bioètica --- Forensic genetics --- Bioethics --- DNA fingerprinting --- Genètica forense
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This reference book comprehensively reviews the significance of DNA technology in forensic science. After presenting the theory, basic principles, tools and techniques that are used in forensic DNA typing, it summarizes various techniques, including autosomal STR, Y-STR, X-STR, mitochondrial DNA and NGS, used in solving both criminal as and civil cases, such as paternity disputes, identification of mutilated remains, and culprit identification in sexual assault and murder cases. It also provides an overview of DNA-based genetic diagnostics for various diseases, and discusses the role of DNA typing in drug reactions, as well as the application of non-human DNA profiling of animals and plants in forensic science investigations. Lastly, the book examines the role of internal quality control in maintaining the high quality of DNA profiling.
DNA fingerprinting --- DNA fingerprinting. --- Technique. --- DNA fingerprints --- DNA identification --- DNA profiles --- DNA profiling --- Genetic fingerprinting --- Genetic fingerprints --- Forensic genetics --- Identification --- Technique --- Ressenya genètica
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This textbook for undergraduate and postgraduate students discusses advancements in forensic DNA analysis since early texts were published. It presents conventional and latest serological and molecular biological methods for body fluid identification. This book also describes the applications and advantages of next-generation sequencing (NGS) compared to conventional methods in forensic DNA analysis. It also defines the growing importance, techniques, and applications for the analysis of non-human DNA in forensic sciences. Further, the book examines the role of DNA databases in forensic interpretation and criminal investigations. Towards the end, this textbook reviews the application of forensic DNA technology in analyzing real-time casework samples and presents the guidelines, ethical issues, and other challenges of forensic DNA analysis. This textbook is an essential resource for students and practitioners interested in gaining knowledge of up-to-date forensic techniques and their applications in forensic DNA analysis.
Genetics. --- Forensic sciences. --- Molecular genetics. --- Genotype. --- Forensic Science. --- Molecular Genetics. --- DNA fingerprinting. --- Forensic genetics.
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