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Chemical genomics
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ISBN: 9781139232012 1139232010 9781139233552 1139233556 9781139021500 1139021508 9781139230551 1139230557 9780521889483 0521889480 110722621X 1139234269 1280568984 9786613598585 1139232770 1139229109 Year: 2012 Publisher: New York : Cambridge University Press,

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Abstract

Advances in chemistry, biology and genomics coupled with laboratory automation and computational technologies have led to the rapid emergence of the multidisciplinary field of chemical genomics. This edited text, with contributions from experts in the field, discusses the new techniques and applications that help further the study of chemical genomics. The beginning chapters provide an overview of the basic principles of chemical biology and chemical genomics. This is followed by a technical section that describes the sources of small-molecule chemicals; the basics of high-throughput screening technologies; and various bioassays for biochemical-, cellular- and organism-based screens. The final chapters connect the chemical genomics field with personalized medicine and the druggable genome for future discovery of new therapeutics. This book will be valuable to researchers, professionals and graduate students in many fields, including biology, biomedicine and chemistry.

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