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Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors, and mRNA instability elements responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated processes involved in mRNA decay and its regulation.

Messenger RNA. --- Genetic regulation. --- Eukaryotic cells. --- Nucleases. --- ARN messager --- Régulation génétique --- Cellules eucaryotes --- Régulation génétique --- Eucaryotic cells --- Gene expression --- Gene expression regulation --- Gene regulation --- Informational RNA --- Messenger ribonucleic acid --- mRNA --- Protein transcript --- Protein transcripts --- Template RNA --- Regulation --- Esterases --- Cells --- Protista --- Biosynthesis --- Cellular control mechanisms --- Molecular genetics --- RNA

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In this second of two new volumes covering mitochondria, methods developed to assess the number and function of nuclear-encoded proteins in the mitochondrion are presented. Chapters focus on the regulation of mitochondrial function and mitochondrial diseases, with a section emphasizing the mitochondrial defects associated with type 2 diabetes.The critically acclaimed laboratory standard for 40 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. With more than 450 volumes published, each volume presents material that is rele

Biochemistry -- Periodicals. --- Enzymes -- Periodicals. --- Enzymes. --- Mitochondria. --- Mitochondrial pathology. --- Mitochondrial Diseases --- Phosphoprotein Phosphatases --- Mitochondria --- Protein Kinases --- Subcellular Fractions --- Phosphoric Monoester Hydrolases --- Organelles --- Metabolic Diseases --- Phosphotransferases (Alcohol Group Acceptor) --- Cellular Structures --- Nutritional and Metabolic Diseases --- Phosphotransferases --- Cytoplasmic Structures --- Esterases --- Hydrolases --- Diseases --- Cells --- Transferases --- Cytoplasm --- Enzymes --- Anatomy --- Intracellular Space --- Enzymes and Coenzymes --- Chemicals and Drugs --- Animal Biochemistry --- Human Anatomy & Physiology --- Health & Biological Sciences --- Phosphoprotein phosphatases. --- Protein kinases. --- Active oxygen. --- Electron transport. --- Phosphoprotein phosphohydrolases --- Protein phosphatases --- Protein phosphoesterases --- Protein phosphohydrolases --- Protein kinase --- Protein phosphotransferases --- Oxygen radicals --- Reactive oxygen --- Singlet oxygen --- Superperoxide anion --- Chondriosomes --- Phosphatases --- Electrons --- Energy-band theory of solids --- Free electron theory of metals --- Transport theory --- Free radicals (Chemistry) --- Ionization of gases --- Oxygen --- Cell organelles --- Protoplasm

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Acyltransferases --- Esterases --- Pharmaceutical Preparations --- Hexosyltransferases --- Metabolism --- Metabolic Phenomena --- Glycosyltransferases --- Transferases --- Hydrolases --- Chemicals and Drugs --- Phenomena and Processes --- Enzymes --- Enzymes and Coenzymes --- Acetyltransferases --- Sulfatases --- Biological Transport --- Glucuronosyltransferase --- Xenobiotics --- Biologic Transport --- Transport, Biological --- Transport, Biologic --- 17 beta-Hydroxysteroid UDP-Glucuronosyltransferase --- 4-Nitrophenol-UDP-Glucuronosyltransferase --- 7-Hydroxycoumarin UDP Glucuronyltransferase --- Androsterone UDP-Glucuronosyltransferase --- Bilirubin UDP-Glucuronyltransferase --- Estrogen UDP-Glucuronosyltransferase --- Estrone Glucuronyltransferase --- Glucuronic Transferase --- Morphine Glucuronyltransferase --- UDP Glucuronyl Transferase --- UDP-Glucuronic Acid 3-O-beta-D-Galactosyl-D-Galactose Glucuronosyltransferase --- p-Nitrophenyl UDP-Glucuronosyltransferase --- Glucuronyltransferase --- UDP Glucuronosyltransferase --- 17 beta Hydroxysteroid UDP Glucuronosyltransferase --- 4 Nitrophenol UDP Glucuronosyltransferase --- 7 Hydroxycoumarin UDP Glucuronyltransferase --- Androsterone UDP Glucuronosyltransferase --- Bilirubin UDP Glucuronyltransferase --- Estrogen UDP Glucuronosyltransferase --- Glucuronosyltransferase, UDP --- Glucuronyl Transferase, UDP --- Glucuronyltransferase, 7-Hydroxycoumarin UDP --- Glucuronyltransferase, Estrone --- Glucuronyltransferase, Morphine --- Transferase, Glucuronic --- Transferase, UDP Glucuronyl --- UDP Glucuronic Acid 3 O beta D Galactosyl D Galactose Glucuronosyltransferase --- UDP Glucuronyltransferase, 7-Hydroxycoumarin --- UDP-Glucuronosyltransferase, 17 beta-Hydroxysteroid --- UDP-Glucuronosyltransferase, Androsterone --- UDP-Glucuronosyltransferase, Estrogen --- UDP-Glucuronosyltransferase, p-Nitrophenyl --- UDP-Glucuronyltransferase, Bilirubin --- p Nitrophenyl UDP Glucuronosyltransferase --- Coenzymes and Enzymes --- Biocatalysts --- Transferase --- Glycoside Transferases --- Transferases, Glycoside --- Metabolic Phenomenon --- Metabolic Process --- Metabolism Concepts --- Metabolism Phenomena --- Process, Metabolic --- Processes, Metabolic --- Anabolism --- Catabolism --- Metabolic Concepts --- Metabolic Processes --- Concept, Metabolic --- Concept, Metabolism --- Concepts, Metabolic --- Concepts, Metabolism --- Metabolic Concept --- Metabolism Concept --- Phenomena, Metabolic --- Phenomena, Metabolism --- Phenomenon, Metabolic --- Pharmaceutic Preparations --- Pharmaceutical Products --- Preparations, Pharmaceutical --- Drugs --- Preparations, Pharmaceutic --- Products, Pharmaceutical