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Myocardium. --- Cardiac Muscle --- Myocardia --- Muscle, Cardiac --- Muscle, Heart --- Cardiac Muscles --- Heart Muscle --- Heart Muscles --- Muscles, Cardiac --- Muscles, Heart --- Heart --- Myocardium

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Cardiac Gene Expression: Methods and Protocols presents both cutting-edge and established methods for studying cardiac gene expression. The protocols provide a template for solid research, and cover the process through screening, analysis, characterization, and functional confirmation of novel genes or known genes with a new function. Section I, Cardiac Gene Expression Profiling: The Global Perspective, discusses several different approaches to examining, identifying, and analyzing changes in transcriptome gene expression. Section II, Cardiac Gene Regulation: Gene-Specific mRNA Measurement in the Myocardium, outlines more sensitive and gene-targeted expression methods. Section III, Cardiac Gene Regulation: Promoter Characterization in the Myocardium, provides protocols for the study of underlying gene regulation mechanisms by focusing on the interaction of transcription factors with their cognate cis binding elements. Section IV, In Silico Assessment of Regulatory cis-Elements and Gene Regulation, and Section V, Cardiac Single Network Polymorphisms, emphasize new analytical approaches for deciphering the functional elements buried in the 3 billion nucleotides of the human genome and other model genomes. The concluding section, Gene Overexpression and Targeting in the Myocardium, highlights methods that facilitate overexpression or cardiac-specific targeted gene deletion.

Myocardium --- Gene expression --- Genetic regulation --- Gene Expression Regulation --- Gene Expression Profiling --- Muscle, Striated --- Cardiac muscle --- Heart muscle --- Gene expression regulation --- Gene regulation --- Biosynthesis --- Cellular control mechanisms --- Molecular genetics --- Genes --- Heart --- Muscles --- Regulation --- Expression --- Muscle --- Biochemistry. --- Human genetics. --- Cardiology. --- Bioinformatics. --- Biochemistry, general. --- Human Genetics. --- Bio-informatics --- Biological informatics --- Biology --- Information science --- Computational biology --- Systems biology --- Internal medicine --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Medical sciences --- Data processing --- Diseases --- Composition --- Myocardium - Laboratory manuals --- Gene expression - Laboratory manuals --- Genetic regulation - Laboratory manuals --- Gene Expression Regulation - laboratory manuals --- Gene Expression Profiling - laboratory manuals --- Myocardium - laboratory manuals