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High throughput analysis for early drug discovery
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ISBN: 9780124311657 0124311652 9780080472928 0080472923 1280966874 9786610966875 Year: 2004 Publisher: Amsterdam ; Boston : Elsevier,

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This book offers concise and unbiased presentations by synthetic and analytical chemists who have been involved in creating and moving the field of combinatorial chemistry into the academic and industrial mainstream. Since the synthetic method often dictates the appropriate types of analysis, each chapter or section begins with a description of the synthesis approach and its advantages.

Combinatorial chemistry: a practical approach
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ISBN: 3527301860 Year: 2000 Publisher: Weinheim Wiley-VCH

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As we enter the new millennium, combinatorial chemistry is providing significant impetus to new innovations in synthetic chemistry. Combinatorial chemistry has rapidly become the rising star among research methods, allowing scientists to efficiently test the feasibility of a multitude of new compounds. The pursuit of new drugs is but one challenging field in which these combinatorial methods are particularly advantageous, helping researchers meet the modern-day demands of a highly competitive environment. This book emphasises that modern combinatorial synthesis is possible not only in the solid phase, but also in solutions. Moreover, it discusses computer-assisted methods as well as the apparatus and instrumentation required for the combinatorial method. Successful and experienced researchers in the leading pharmaceutical companies and most renowned research institutes offer a solid insight and perspective into this diverse field. A 'must' for every scientist in the area of pharmaceutical research.


Periodical
Combinatorial chemistry : an online journal.
ISSN: 14643383 Year: 1998 Publisher: [Amsterdam, Netherlands?] : Elsevier Science,

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A WWW only publication which contains articles on combinatorial chemistry accepted for publication in: Tetrahedron, Tetrahedron Letters, Tetrahedron:Asymmetry, Bioorganic & Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters, CarbohydrateResearch, and other relevant Elsevier Science journals. It also features specially commissioned topical reports, as well as abstracts of articles from other publications. Articles are designated with page number and are published continuously in annual volumes.

Experimental design for combinatorial and high throughput materials development
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ISBN: 0471203432 Year: 2003 Publisher: Hoboken, N.J. Wiley

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In the past decade, combinatorial and high throughput experimental methods have revolutionized the pharmaceutical industry, allowing researchers to conduct more experiments in a week than was previously possible in a year. Now high throughput experimentation is rapidly spreading from its origins in the pharmaceutical world to larger industrial research establishments such as GE and DuPont, and even to smaller companies and universities. Consequently, researchers need to know the kinds of problems, desired outcomes, and appropriate patterns for these new strategies. Editor James Cawse's far-reaching study identifies and applies, with specific examples, these important new principles and techniques. Experimental Design for Combinatorial and High Throughput Materials Development progresses from methods that are now standard, such as gradient arrays, to mathematical developments that are breaking new ground. The former will be particularly useful to researchers entering the field, while the latter should inspire and challenge advanced practitioners. The book's contents are contributed by leading researchers in their respective fields. Chapters include: -High Throughput Synthetic Approaches for the Investigation of Inorganic Phase Space -Combinatorial Mapping of Polymer Blends Phase Behavior -Split-Plot Designs -Artificial Neural Networks in Catalyst Development -The Monte Carlo Approach to Library Design and Redesign This book also contains over 200 useful charts and drawings. Industrial chemists, chemical engineers, materials scientists, and physicists working in combinatorial and high throughput chemistry will find James Cawse's study to be an invaluable resource.


Periodical
Lab on a chip
Author:
ISSN: 14730197 14730189 Publisher: Royal society of chemistry

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Keywords

57.081.2 --- 57 --- 542 <05> --- 57.081.2 Automation of biological experiments --- Automation of biological experiments --- 542 <05> Practical laboratory chemistry. Preparative and experimental chemistry--Tijdschriften --- Practical laboratory chemistry. Preparative and experimental chemistry--Tijdschriften --- Biological sciences in general --- Periodicals --- Chemical laboratories --- Miniature electronic equipment --- Combinatorial chemistry --- Biotechnology --- Nanotechnology --- Nanotechnology. --- Biotechnology. --- Microchemistry. --- Miniaturization. --- Équipement électronique miniaturisé --- Chimie combinatoire --- Biotechnologie --- Combinatorial chemistry. --- Miniature electronic equipment. --- Microélectronique. --- Appareil électronique. --- Biotechnologie. --- Chimie combinatoire. --- Electronic equipment, Miniature --- Microminiaturization (Electronics) --- Miniaturization (Electronics) --- Subminiature electronic equipment --- Subminiaturization (Electronics) --- Electronic apparatus and appliances --- Microelectronics --- Combinatorial organic synthesis --- Combinatorial synthesis (Organic chemistry) --- High-throughput organic synthesis --- High-throughput synthesis (Organic chemistry) --- Multiple parallel synthesis (Organic chemistry) --- Organic compounds --- Pharmaceutical chemistry --- Biochips --- Chemical engineering --- Genetic engineering --- Miniaturisation --- Miniaturisations --- Miniaturizations --- Microchemistry --- Miniaturization --- Biosensing Techniques --- Lab-On-A-Chip Devices --- Biotechnologies --- Chemistry laboratories --- Laboratories --- Nanotechnologies --- Nanotubes --- Microchip Analytical Procedures --- Nanostructures --- Electronic equipment --- Synthesis --- Molecular technology --- Nanoscale technology --- High technology --- Electronic equipment. --- Chemistry --- Engineering --- Life Sciences --- General and Others --- Electrical Engineering --- Computational Biosciences

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