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Free radicals have been implicated in a entire host of different human disease states, which suggests that although they may not have a pivotal causal role, they are involved in the perpetuation of disease. In recent years, it has become evident that although free radicals most certainly do have this role in perpetuating inflammatory reactions, they have perhaps a far more important role in acting as second messenger systems to maintain normal cell function. It is the perturbations of these reactions which pose the most intriguing therapeutic challenges.
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General Aspects of the Chemistry of Radicals Edited by Z. B. Alfassi Ben Gurion University of the Negev, Israel Free radicals are used as reactive intermediates in a wide range of organic syntheses as well as playing an important role in biological systems and industrial processes. Free radical chemistry is a rapidly developing area, with applications not only in chemistry but also in processes related to the environment, biology, drug research and medicine. General Aspects of the Chemistry of Radicals is an introductory book, discussing methods of formation and detection of free radicals, the rate of their reactions and their thermochemistry. The book closely examines the reactivity of free radical reactions, rate constants and temperature dependence, important in predicting the behaviour of yet unstudied systems and validating reaction mechanisms. General Aspects of the Chemistry of Radicals is written for researchers working in environmental and material sciences, organic, inorganic and physical organic chemistry. It will also be of interest to biochemists and molecular biologists working with the effects of free radicals on living systems.
Chemical thermodynamics --- fysicochemie --- Free radicals (Chemistry) --- Free radicals (Chemistry). --- Radicals (Chemistry) --- Free radical reactions
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