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The tools of molecular biology have revolutionised our understanding of gene structure and function and changed the teaching of genetics in a fundamental way. The transition from classical genetics to molecular genetics was initiated by two discoveries. One was the discovery that DNA has a complementary double helix structure and the other that a universal genetic code does exist. Both led to the acceptance of the central dogma that RNA molecules are made on DNA templates. The last twenty years have seen remarkable growth in our knowledge of molecular genetics, most of which is the outcome
Molecular biology --- Molecular genetics. --- Biochemical genetics.
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Molecular biology --- Proteins --- Biochemical genetics --- Molecular evolution --- Biochemical genetics. --- Molecular evolution. --- Proteins.
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Biochemical genetics --- Chemical genetics --- Biochemistry --- Molecular genetics --- Biochemical genetics. --- Animal --- animals --- Molecular Biology --- Biochemical Genetics --- Biology, Molecular --- Genetics, Biochemical --- Genetics, Molecular --- Molecular Genetics --- Biochemical Genetic --- Genetic, Biochemical --- Genetic, Molecular --- Molecular Genetic --- Genetic Phenomena --- Molecular biology --- genetics --- biochemistry --- Genetique biochimique
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Human genetics --- Pathology of the metabolism --- Molecular biology --- Human biochemistry --- Biochemical genetics. --- Human genetics. --- Genetics, medical. --- Biology --- Biological Science Disciplines --- Genetics, Biochemical --- Biochemical genetics
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Pharmacogenetics, the use of genetic testing to prescribe and develop drugs, has been hailed as a revolutionary development for the pharmaceutical industry and modern medicine. Supporters of 'personalised medicine' claim the result will be safer, cheaper, more effective drugs, and their arguments are beginning to influence policy debates. Based on interviews with clinicians, researchers, regulators and company representatives, this book explores the impact of pharmacogenetics on clinical practice, following two cases of personalised medicine as they make their way from the laboratory to the clinic. It highlights the significant differences between the views of supporters of pharmacogenetics in industry and those who use the technology at the clinical 'coal face'. Theoretically, this work builds on the developing area of the sociology of socio-technical expectations, highlighting the way in which promoters of new technologies build expectations around it, through citation and the creation of technological visions.
Sociology of health --- Pharmacology. Therapy --- Social Sciences --- Sociology --- Pharmacogenetics --- Social aspects. --- Pharmacology --- Biochemical genetics --- Genetic aspects
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Enzymology --- Animal embryology and growth --- Molecular biology --- Insects. Springtails --- Biochemical genetics. --- Drosophila. --- Enzymes. --- Insects --- Drosophila --- Eye. --- Genes. --- Mutation. --- Genetics. --- Enzymology.
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Currently Drosophila is a dominant experimental model in developmental biology and in gene regulation in eukaryotes. This volume summarizes some thirty years of experience in the handling of in vitro cultured Drosophila cells. Its main emphasis is on gene transfer methodology, cell responses to heat shock, hormonal regulation of genes, and on the expression and mobility of transposable elements.Key Features* Some thirty years of experience in handling in vitro cultured Drosophila cells* Cell cultures which provide material for a multiplicity o
Histology. Cytology --- Biochemical genetics. --- Drosophila --- Cytology --- Technique. --- Cell Culture Techniques. --- Cells, Cultured. --- cytology. --- ELSEVIER-B EPUB-LIV-FT
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'DNA Repair, ' Volume 115 in the Advances in Protein Chemistry and Structural Biology series, provides an overview of current developments in mechanisms underlying DNA repair, their involvement in maintaining chromatin repair, the balance between chromosome breaks repair pathways, tumorigenesis, immune signaling and infection-induced inflammation. Specific chapters cover the Structure and function of the multi-subunit TFIIH with insights into nucleotide excision repair, Chromatin repair: how DNA packaging controls double-strand break repair, Controlling the balance between chromosome breaks repair pathways, The targeting of DNA repair pathways in the era of precision oncology, and much more. Key Features: Describes advances in our understanding on DNA repair mechanisms and the involvement of their dysregulation in promoting diseases; Presents data that is targeted to a very wide audience of specialists, researchers and students; Contains timely chapters written by well-renowned authorities in their field; Provides targeted information that is well supported by a number of high-quality illustrations, figures and tables. Readership: Protein chemists, biochemists, molecular biologists, cell biologists, immunologists, neuroscientists, structural biologists, medical doctors, pharmacologists, computational biochemists and other researchers working in this field. Articles published here would also be of a great benefit to medical, biology and pharmacology students specializing in this field. -- Provided by publisher.
Documentation and information --- Russian Federation --- Libraries --- Russia --- DNA repair. --- Deoxyribonucleic acid repair --- Repair, DNA --- Repair mechanisms in DNA --- Biochemical genetics --- Antimutagens --- DNA Repair.
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Botanical chemistry --- Chimie végétale --- Botanical chemistry. --- Phytochemistry --- Plant biochemistry --- Plant chemistry --- Biochemistry --- Botany --- Phytochemicals --- Plant biochemical genetics --- Life Sciences --- Plant Physiology --- Chimie végétale
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Human genetics --- Molecular biology --- Genetics, Biochemical --- Genetics, Human --- Biochemical genetics --- Génétique humaine --- Génétique biochimique --- Biochemical genetics. --- Human genetics. --- Molecular Biology. --- Genetics, Medical. --- Génétique humaine --- Génétique biochimique --- Chemical genetics --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology --- Biochemistry --- Molecular genetics
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