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Organic compounds --- Solubility. --- Compounds, Organic --- Organic chemicals --- Carbon compounds

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Chemical technology --- membranen (chemische technologie) --- 541.8 --- Membranes (Technology) --- Artificial membranes --- Separation (Technology) --- Technology --- Solutions and solubility in general --- Membranes (Technology). --- 541.8 Solutions and solubility in general

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Most fields of science, applied science, engineering, and technology deal with solutions in water. This volume is a comprehensive treatment of the aqueous solution chemistry of all the elements. The information on each element is centered around an E-pH diagram which is a novel aid to understanding. The contents are especially pertinent to agriculture, analytical chemistry, biochemistry, biology, biomedical science and engineering, chemical engineering, geochemistry, inorganic chemistry, environmental science and engineering, food science, materials science, mining engineering, metallurgy, nuclear science and engineering, nutrition, plant science, safety, and toxicology.

Solution (Chemistry) --- Inorganic compounds --- Chemical elements --- Elements, Chemical --- Compounds, Inorganic --- Inorganic chemicals --- Chemicals --- Chemistry, Inorganic --- Salt solutions --- Chemistry --- Chemistry, Physical and theoretical --- Matter --- Mixtures --- Cryoscopy --- Osmosis --- Solubility. --- Properties --- Solubility --- Solucions (Química) --- Compostos inorgànics --- Solubilitat --- Lipofília --- Mescles --- Solubilitat dels medicaments --- Productes químics inorgànics --- Productes químics --- Àcids inorgànics --- Química inorgànica --- Dissolucions --- Solució (Química) --- Química física --- Col·loides --- Difusió --- Dissolvents --- Electròlisi --- Extracció (Química) --- Ions --- Suspensions (Química) --- Solucions electrolítiques --- Solucions iòniques --- Solucions polimèriques --- Solvatació --- Crioscòpia --- Osmosi --- Inorganic compounds - Solubility --- Chemical elements - Solubility

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A pharmaceutical scientist’s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound’s physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at minimum a working knowledge of each of the abovementioned facets and detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop. There are numerous literature resources available to pharmaceutical scientists to educate and provide guidance toward formulations development with poorly water-soluble drugs; however, a single, comprehensive reference is lacking. Furthermore, without access to a vast journal library, the detailed methods used to implement these approaches are not available. The objective of this volume is therefore to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules.

Drug development. --- Drugs -- Design. --- Drug development --- Drugs --- Physicochemical Phenomena --- Pharmacokinetics --- Technology, Pharmaceutical --- Pharmacology --- Chemical Processes --- Chemistry --- Investigative Techniques --- Chemical Phenomena --- Biological Science Disciplines --- Natural Science Disciplines --- Metabolic Phenomena --- Pharmacological Phenomena --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Disciplines and Occupations --- Phenomena and Processes --- Physiological Phenomena --- Physicochemical Processes --- Solubility --- Chemistry, Pharmaceutical --- Biological Availability --- Drug Compounding --- Health & Biological Sciences --- Pharmacy, Therapeutics, & Pharmacology --- Design --- Solutions (Pharmacy) --- Solubility. --- Drug solubility --- Dissolution --- Medicine. --- Pharmaceutical technology. --- Biomedicine. --- Pharmaceutical Sciences/Technology. --- Dosage forms --- Pharmaceutical laboratory techniques --- Pharmaceutical laboratory technology --- Technology

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Contributions featuring the chemistry and applications of a family of macrocyclic compounds collectively known as 'calixarenes' are presented in this edited volume. The arsenal of structures based on calixarenes provides tools which are effective in numerous areas of supramolecular chemistry. The Editors have compiled a timely volume which contains up to date, high calibre contributions from a large number of international authors. A broad perspective on the progress and future of calixarene chemistry is presented. Aimed at students and researchers active in Supramolecular Chemistry.

Chemistry. --- Inorganic chemistry. --- Organometallic chemistry. --- Inorganic Chemistry. --- Organometallic Chemistry. --- Calixarenes --- Solubility. --- Aromatic compounds --- Macrocyclic compounds --- Phenols --- Chemistry, inorganic. --- Chemistry, Organic. --- Organic chemistry --- Chemistry --- Inorganic chemistry --- Inorganic compounds --- Organometallic chemistry . --- Chemistry, Organometallic --- Metallo-organic chemistry --- Chemistry, Organic