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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
IORT --- dosimetry --- physics --- radiobiology --- Intrabeam --- breast cancer --- head and neck cancer --- pancreas cancer --- brain metastasis
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Pancreatic Neoplasms. --- Pancreas --- Pancréas --- Cancer --- Periodicals --- Périodiques --- Cancer. --- Cancer of the Pancreas --- Neoplasms, Pancreatic --- Pancreas Cancer --- Pancreas Neoplasms --- Cancer of Pancreas --- Pancreatic Cancer --- Cancer, Pancreas --- Cancer, Pancreatic --- Cancers, Pancreas --- Cancers, Pancreatic --- Neoplasm, Pancreas --- Neoplasm, Pancreatic --- Neoplasms, Pancreas --- Pancreas Cancers --- Pancreas Neoplasm --- Pancreatic Cancers --- Pancreatic Neoplasm --- Medical Oncology. --- Clinical Oncology --- Oncology, Medical --- Oncology, Clinical --- Digestive organs --- Endocrine glands --- Exocrine glands
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Uncommon tumors of the pancreas are of increasing interest for clinicians: cross imaging techniques development makes it possible to detect small lesions in the pancreatic gland of asymptomatic patients, and in the last decades a more detailed and specific pathological classification definitivelyopened an unexpected world of more or less rare pancreatic tumors. As a matter of fact, nowadays most surgical procedures deal with these so called uncommon pancreatic tumors such as cystic, endocrine and others unfrequent histotypes, and many patientsexperiencing an accidental discovery of this type of tumor need therefore a specialistic evaluation. The concept behind this volume is the need to give the correct clinical relevance to these “uncommon” tumors, that are ranked at the first place among pancreatic tumors, and that are definitively curable with a multimodal approach. Aim of the book is therefore to get clinicians closer to these pathologies, describing their complexity and the current state of the art in diagnostic, therapeutic and pathological classification strategy, thus providing them with the tools for a modern and updated clinical management of these patients.
Pancreas -- Cancer. --- Pancreas. --- Pancreatic Neoplasms. --- Endocrine Gland Neoplasms --- Digestive System Neoplasms --- Pancreatic Diseases --- Endocrine System Diseases --- Neoplasms by Site --- Digestive System Diseases --- Diseases --- Neoplasms --- Pancreatic Neoplasms --- Medicine --- Surgery & Anesthesiology --- Health & Biological Sciences --- Oncology --- Surgery - General and By Type --- Pancreas --- Tumors. --- Medicine. --- Surgery. --- Medicine & Public Health. --- Surgery, Primitive
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Pancreas --- Cancer. --- Pancreatic Neoplasms --- Cancer of the Pancreas --- Neoplasms, Pancreatic --- Pancreas Cancer --- Pancreas Neoplasms --- Cancer of Pancreas --- Pancreatic Cancer --- Cancer, Pancreas --- Cancer, Pancreatic --- Cancers, Pancreas --- Cancers, Pancreatic --- Neoplasm, Pancreas --- Neoplasm, Pancreatic --- Neoplasms, Pancreas --- Pancreas Cancers --- Pancreas Neoplasm --- Pancreatic Cancers --- Pancreatic Neoplasm --- Pancreatic Neoplasms. --- Cancer --- pancreas --- pancreatic cancer --- peripancreatic region --- oncology --- Oncology. Neoplasms --- Digestive organs --- Endocrine glands --- Exocrine glands --- Oncology --- Càncer de pàncrees. --- Càncer
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Pancreatic cancer is a growing source of cancer-related death and has poor survival rates, which have not improved in the last few decades. Its high-mortality rate is attributed to pancreatic cancer biology, difficulty in early diagnosis, and lack of standardized international guidelines in assessing the pancreatic masses. This book aims to provide an update in the current state of play in pancreatic cancer diagnosis and to evaluate the benefits and limitations of the available diagnostic technology and therapy. The main modalities for diagnosis are imaging with HCT, MRI, USE, and PET. Some chapters review the improvements in the techniques used. Timely and accurate diagnosis of pancreatic cancer can lead to improve in the current poor outcome of this disease.
Pancreas --- Cancer. --- Pancreatic Neoplasms. --- Cancer of the Pancreas --- Neoplasms, Pancreatic --- Pancreas Cancer --- Pancreas Neoplasms --- Cancer of Pancreas --- Pancreatic Cancer --- Cancer, Pancreas --- Cancer, Pancreatic --- Cancers, Pancreas --- Cancers, Pancreatic --- Neoplasm, Pancreas --- Neoplasm, Pancreatic --- Neoplasms, Pancreas --- Pancreas Cancers --- Pancreas Neoplasm --- Pancreatic Cancers --- Pancreatic Neoplasm --- Medicine --- Gastrointestinal Oncology --- Oncology --- Health Sciences
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Pancreatic cancer is a formidable disease, and advances in early detection and improved therapeutics have been slow to come forth. With new advances in molecular genetics in the field of pancreatic tumorigenesis, it is an opportune time to use these recent discoveries to enhance our understanding of pancreatic cancer biology and to improve outcomes in patients. In this volume, leading experts in the field shed light on these findings describing the mutational landscape of pancreatic cancer, including new inroads into our understanding of familial pancreatic cancer, epidemiology, the biology of K-ras signaling, and the emerging contribution of epigenetic alterations to disease initiation and progression. The distinctive pancreatic cancer-stroma ecosystem as determined by the dynamic interplay of inflammation, hallmark mutations, EMT, and cancer stem cells is described, and implications of these interactions in the context of development of novel, personalized therapeutic options are explored.
Medicine. --- Pancreas -- Cancer -- Genetic aspects. --- Pancreatic neoplasms -- Genetics. --- Pancreas --- Biochemistry --- Digestive System Neoplasms --- Biology --- Neoplasms by Site --- Biological Science Disciplines --- Natural Science Disciplines --- Neoplasms --- Disciplines and Occupations --- Diseases --- Genetics --- Molecular Biology --- Pancreatic Neoplasms --- Medicine --- Health & Biological Sciences --- Oncology --- Molecular aspects --- Cancer --- Genetic aspects --- Molecular aspects. --- Genetic aspects. --- Cancer genetics --- Cancer research. --- Human genetics. --- Cell biology. --- Biomedicine. --- Cancer Research. --- Cell Biology. --- Human Genetics. --- Cancer genes --- Oncology. --- Cytology. --- Heredity, Human --- Human biology --- Physical anthropology --- Tumors --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Cancer research
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Although interest in pancreatic pathology is very high in the radiological and gastroenterological communities, it is still the case that less is known about pathology of the pancreas than about liver pathology, for example. Diagnosis depends on the structure of the pancreatic lesion, which can be directly visualized on US, CT or MR images. This atlas, which encompasses both the imaging and the pathology of pancreatic neoplasms, will therefore be invaluable in enabling radiologists and sonographers to understand the underlying pathology and in allowing pancreatic pathologists to understand the imaging translation. The emphasis in the atlas is very much on the pathological and imaging appearances, with most of the text concentrated at the beginning of the chapters. A comprehensive overview is provided of typical and atypical presentations and diverse aspects of common and uncommon pancreatic neoplasms, including ductal adenocarcinoma, neuroendocrine neoplasms, intraductal papillary mucinous neoplasms, cystic neoplasms, metastases and lymphoma.
Medicine & Public Health. --- Imaging / Radiology. --- Pathology. --- Surgical Oncology. --- Medicine. --- Radiology, Medical. --- Cancer --- Médecine --- Pathologie --- Surgery. --- Chirurgie --- Cancer_xSurgery. --- Medicine --- Health & Biological Sciences --- Radiology, MRI, Ultrasonography & Medical Physics --- Pancreas --- Tumors. --- Imaging. --- Imaging of cancer --- Radiology. --- Surgical oncology. --- Oncologic surgery --- Oncological surgery --- Surgical oncology --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine, Preventive --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics --- Excision --- Treatment --- Radiological physics --- Physics --- Radiation --- Pancreatic Neoplasms --- Diagnostic Imaging --- duagbisus, --- pathology. --- methods. --- Cancer of the Pancreas --- Neoplasms, Pancreatic --- Pancreas Cancer --- Pancreas Neoplasms --- Cancer of Pancreas --- Pancreatic Cancer --- Cancer, Pancreas --- Cancer, Pancreatic --- Cancers, Pancreas --- Cancers, Pancreatic --- Neoplasm, Pancreas --- Neoplasm, Pancreatic --- Neoplasms, Pancreas --- Pancreas Cancers --- Pancreas Neoplasm --- Pancreatic Cancers --- Pancreatic Neoplasm
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