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Book
Ins and Outs of miRNAs as Biomarkers
Authors: ---
Year: 2023 Publisher: Basel : MDPI - Multidisciplinary Digital Publishing Institute,

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Abstract

miRNAs are small noncoding RNAs that control gene expression at the post-transcriptional level. It has been recognized that dysregulation of miRNAs reflects the state and function of cells and tissues, contributing to their dysfunction. The identification of hundreds of extracellular miRNAs in biological fluids has underscored their potential in the field of biomarker research. In addition, the therapeutic potential of miRNAs is receiving increasing attention in numerous conditions. On the other hand, many operational issues, including stability, delivery systems, and bioavailability, have yet to be resolved. In this dynamic field, biopharmaceutical companies are increasingly engaged, and ongoing clinical trials point to anti-miR and miR-mimic molecules as novel classes of molecules for upcoming therapeutic applications. This reprint aims to provide a broad overview of current knowledge on several outstanding issues and new opportunities offered by miRNAs in the treatment of diseases and as early diagnostic tools for next-generation medicine.


Book
Hypothermia
Authors: ---
ISBN: 9781619425644 1619425645 9781619425514 1619425513 Year: 2012 Publisher: New York

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Book
More than hot : a short history of fever
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ISBN: 1421415038 9781421415031 9781421415024 142141502X Year: 2014 Publisher: Baltimore, Maryland : Johns Hopkins University Press,

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Book
Febrile seizures : new concepts and consequences
Authors: --- ---
ISBN: 0323899323 0323984185 9780323899321 9780323984188 Year: 2022 Publisher: Amsterdam, Netherlands : Elsevier,

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Periodical
Journal of thermal biology
ISSN: 18790992 03064565 Year: 1975 Publisher: [Oxford ; New York] : Pergamon


Book
Thermoregulation. : from basic neuroscience to clinical neurology
Author:
ISBN: 0444639136 0444639128 9780444639134 9780444640758 0444640754 0444640746 9780444640741 9780444639127 Year: 2018 Publisher: Amsterdam : Elsevier,

Body heat
Author:
ISBN: 0674023765 9780674023765 9780674007628 067400762X 0674013697 9780674013698 0674262123 9780674262126 Year: 2002 Publisher: Cambridge, Mass. Harvard University Press

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In this illuminating book, biopsychologist Mark Blumberg explores the many ways that temperature rules the lives of all animals. In the process Blumberg tells wonderful stories of evolutionary and scientific ingenuity.


Book
Fever : its biology, evolution, and function
Author:
ISBN: 0691082340 9781400869831 1400869838 9780691608600 9780691082349 0691608601 9780691082349 Year: 1979 Publisher: Princeton, New Jersey : Princeton University Press,

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Fever has long been recognized as a symptom of disease. Until the past century it was considered a healthy sign; since then this view has changed and the use of drugs to reduce fever has grown quite common. Acting on the revival of interest as to whether the effects of fever are beneficial or harmful, Matthew Kluger and other physiologists began a series of experiments designed to resolve this question. This book synthesizes their research, making a case not only for the beneficial function of fever but also for the re-evaluation of current clinical practices regarding fever.Originally published in 1979.The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.


Book
Thermische verletzungen im Kindesalter
Authors: ---
ISBN: 3110434997 3110436035 9783110436037 9783110436044 3110436043 3110442841 9783110434996 Year: 2016 Publisher: Berlin, [Germany] ; Boston, [Massachusetts] : De Gruyter,

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Burns and scalds in childhood require specialized acute treatment as well as continuous aftercare. This book offers a detailed presentation of the therapeutic strategies in surgery, pediatrics, nursing, rehabilitation and psychology that are necessary to prevent permanent psychological traumatization and long-term aesthetic or functional impairment. Um ein optimales Therapieziel ohne dauerhafte psychische Traumatisierung und ästhetische bzw. funktionelle Langzeitfolgen zu erreichen, sollte jede Behandlung von thermisch verletzten Kindern interdisziplinär durch ein Team aus Kinderchirurgen, Plastischen Chirurgen, Pädiatern und Pflegenden in Kooperation mit Physiotherapeuten, Ergotherapeuten, Orthopädietechnikern und Psychologen erfolgen.Erstmalig wird diese Interdisziplinarität in einem Buch abgebildet. Zentraler Fokus bilden die Erst- und Akutversorgung sowie die Intensivmedizin, die spezielle Pflege und Rehabilitation brandverletzter Kinder, aber auch sekundärchirurgische Maßnahmen. Gesondert beschrieben werden sozialpädiatrische und psychologische Aspekte, ebenso wie die Einbindung der Eltern im Selbsthilfeverein. Eingerahmt wird die Thematik von Kapiteln zur Epidemiologie, Pathophysiologie, Arten thermischer Verletzungen (inkl. Kindeswohlgefährdung), Prävention und Strukturvoraussetzungen für versorgende Einrichtungen.

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