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Assessing the human health risks of trichloroethylene
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ISBN: 128074247X 9786610742479 0309663601 9780309663601 0309102839 9780309102834 6610742472 Year: 2006 Publisher: Washington, D.C. National Academies Press

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Abstract


Book
Trichloroethylene: Toxicity and Health Risks
Authors: ---
ISBN: 1447163109 1447163117 Year: 2014 Publisher: London : Springer London : Imprint: Springer,

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Abstract

A comprehensive overview of the effects of trichloroethylene toxicity caused by real-life exposure levels highlighting how exposure to trichloroethylene may contribute to the etiology of several idiopathic human diseases. Discussion will focus on different kinds of modeling and how they may be used to predict functional consequences and to dissect the contribution of different mechanistic pathways, including potential mechanisms of action for trichloroethylene toxicity in different organ systems. It will explore the role of epigenetic alterations in trichloroethylene toxicity, this provides important mechanistic information and may also provide the basis for intervention therapy. Chapters will also explain how the risks from trichloroethylene exposure may be greater in certain populations based on genetic predisposition, age of exposure and co-exposure to other chemicals With contributions from international experts in the field, Trichloroethylene: Toxicity and Health Risks is an essential resource for researchers and clinicians in toxicology, immunology, medicine and public health as well as industry and government regulatory scientists involved in safety and health protection and epidemiologists, highlighting the need for interdisciplinary cooperation in solving issues of environmental toxicity.

Keywords

Trichloroethylene -- Environmental aspects. --- Trichloroethylene -- Physiological effect. --- Trichloroethylene -- Toxicology. --- Trichloroethylene --- Hydrocarbons, Chlorinated --- Hydrocarbons, Halogenated --- Hydrocarbons --- Organic Chemicals --- Chemicals and Drugs --- Public Health --- Health & Biological Sciences --- Pharmacy, Therapeutics, & Pharmacology --- Toxicology & Public Health --- Toxicology --- Physiological effect --- Environmental aspects --- Toxicology. --- Environmental aspects. --- Physiological effect. --- Acetylene trichloride --- Ethinyl trichloride --- TCE (Trichloroethylene) --- Trethylene --- Tri (Chemical) --- Trichlorethylene --- Trichloroethene --- Triclene --- Trilene --- Trimar --- Medicine. --- Immunology. --- Molecular biology. --- Pharmacology. --- Medical biochemistry. --- Epidemiology. --- Environmental health. --- Biomedicine. --- Pharmacology/Toxicology. --- Molecular Medicine. --- Medical Biochemistry. --- Environmental Health. --- Anesthetics --- Chlorohydrocarbons --- Ethylene --- Biochemistry. --- Environmental Medicine. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Immunobiology --- Life sciences --- Serology --- Clinical sciences --- Medical profession --- Human biology --- Pathology --- Physicians --- Diseases --- Public health --- Chemicals --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Composition --- Health Workforce --- Environmental quality --- Health --- Health ecology --- Environmental engineering --- Health risk assessment --- Medical biochemistry --- Pathobiochemistry --- Pathological biochemistry --- Biochemistry --- Molecular biochemistry --- Molecular biophysics --- Biophysics --- Biomolecules --- Systems biology --- Drug effects --- Medical pharmacology --- Chemotherapy --- Drugs --- Pharmacy --- Health aspects

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