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Radiobiology --- Radiation Effects. --- Radiobiology.

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Space radiobiology --- Space biology --- Biological Science Disciplines. --- Extraterrestrial Environment. --- Ecological Systems, Closed. --- Radiation Effects. --- Space biology. --- Space radiobiology.

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The DNA of mammalian cells is constantly under assault from both endogenous and exogenous sources.  Ionizing radiation is one of the most important sources of genomic injury because of its ability to inflict substantial cellular damage that is both therapeutic as well as mutagenic.  Mammalian cells have evolved an impressive array of DNA damage response mechanisms that are called upon to respond to and repair radiation-induced DNA injury that allow cells to survive with DNA fidelity intact.  Contemporary oncologic research and patient management demand a thorough understanding of these DNA damage response processes as well as some of the important environmental conditions like hypoxia in which cells exist such that strategies that subvert these survival processes can be considered and exploited for therapeutic gain. Molecular Determinants of Radiation Response includes chapters by expert authors who detail the present understanding of key DNA damage response pathways and proteins.  The chapters include comprehensive discussions on where and how specific alterations in function of these pathways and proteins result in substantive modifications of cellular response to DNA injury.   The authors have done a wonderful job in providing meaningful reviews, with appropriate detail and scope for both the well informed reader as well as the novice looking for new information.  Given the importance of therapies that induce DNA injury in the management of human disease, this book is timely and relevant for basic and translational researchers, as well as clinicians alike.

DNA damage -- Radiation effects. --- DNA damage. --- DNA repair -- Radiation effects. --- Neoplasms -- Radiotherapy. --- Signal transduction -- Radiation effects. --- DNA damage --- Genetic Processes --- Biochemical Processes --- Radiation --- Therapeutics --- Diseases --- Cell Physiological Processes --- Chemical Processes --- Cell Physiological Phenomena --- Genetic Phenomena --- Biochemical Phenomena --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Electromagnetic Phenomena --- Physical Phenomena --- Chemical Phenomena --- Phenomena and Processes --- DNA Repair --- DNA Damage --- Neoplasms --- Signal Transduction --- Radiation Effects --- Radiotherapy --- Biology --- Medicine --- Health & Biological Sciences --- Genetics --- Oncology --- Cancer --- Radiotherapy. --- Medicine. --- Cancer research. --- Pharmacology. --- Biomedicine. --- Cancer Research. --- Pharmacology/Toxicology. --- Treatment --- Oncology. --- Toxicology. --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Tumors --- Toxicology --- Cancer research --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemotherapy --- Drugs --- Pharmacy --- Physiological effect

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Nuclear medicine --- Médecine nucléaire --- Periodicals --- Périodiques --- Nuclear Medicine. --- Nuclear medicine. --- Asia. --- Oceania. --- radiopharmacy --- radiochemistry --- animal studies --- radiation effects --- image processing --- Medicine, Atomic --- Medicine, Nuclear --- Radiology, Nuclear --- Atomic Medicine --- Nuclear Radiology --- Nuclear Pharmacy --- Radiobiology --- Atomic medicine --- Radioisotopes in medicine --- Medical radiology --- Radioactive tracers --- Radioactivity --- Physiological effect --- Biology --- Physical methods for diagnosis --- Radiology, MRI, Ultrasonography & Medical Physics

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Radiobiology --- Radiation --- Radiobiologie --- Rayonnement --- Periodicals --- Périodiques --- Radiation. --- Radiobiology. --- Chemistry --- Life Sciences --- Biochemistry --- Biology --- radiation effects --- oncology --- physics --- chemistry --- biology --- environmental sciences --- Radiations --- Dose Hypofractionation --- Physics --- Radiology --- Radiation biology --- Biophysics --- Nuclear physics --- Environmental Health. --- Environmental Health Science --- Health, Environmental --- Environmental Health Sciences --- Environmental Healths --- Health Science, Environmental --- Health Sciences, Environmental --- Healths, Environmental --- Science, Environmental Health --- Sciences, Environmental Health --- Ecology --- Radiation Dose Hypofractionation --- Radiobiologia --- Radiació --- Radiobiologia. --- Radiació.