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New technologies have revealed previously unknown and invisible parts of the human body and made it visible at the molecular level, revealing in turn more detailed structures and arrangements than those which were previously available. In doing so, in many ways they refine, expand, and even completely overturn forms of contemporary knowledge. This book maps the shifts and blurring of boundaries in contemporary bioscientific discourse. The authors of its chapters trace the shifts of boundaries in terms of the gradual blurring of the validity of established concepts, interpretive frameworks, and standards of judgment, which are analysed from ontological, gnoseological, ethical, and social perspectives. At the same time, they also map the blurring of boundaries in terms of the interdisciplinary crossing of boundaries between various scientific and artistic disciplines. The shifting of boundaries ultimately forms a part of these boundaries' definition; upon the basis of a rationally guided discussion, these shifts can be guided and corrected so as to avoid any irreversible damage. Jana Tomašovičová is a philosopher with a special interest in contemporary philosophy and bioethics. She analyses the impact of biotechnology on traditional social, ethical, and anthropological concepts and their relevance in new conditions. She is an associate professor at the Faculty of Arts, University of Ss. Cyril and Methodius in Trnava, Slovakia. During her bioethics research, she conducted short research stays at the universities of Bonn, Heidelberg, Tübingen, and Zürich.

Science --- Bioethic --- Ontology --- New technologies --- Human Enhancemen --- Interdisciplinarity

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The wide range of topics that the book covers are organised into sections reflecting a cradle to grave view of how entrepreneurial, innovative, and tech-savvy approaches can advance environmental sustainability in the fashion sector. These sections include: sustainable materials; innovation in design, range planning and product development; sustainable innovations in fashion supply chains; sustainable innovations in fashion retail and marketing; sustainable alternatives for end-of-life and circular economy initiatives; and more sustainable alternative fashion business models.

BUSINESS & ECONOMICS / Development / Sustainable Development. --- Business Models. --- Circular Economy. --- Cradle to Grave. --- Digitization. --- New technologies. --- Product Development. --- Product Life-Cycles.

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Population aging and the associated burden of chronic diseases are one of the main challenges in public health worldwide. This Research Topic on "Active Aging and Disease Management" provides a comprehensive overview of population aging through fourteen comprehensive papers. Chapter 1 discusses an overview of health systems in active and healthy aging, while Chapter 2 focuses on the role of lifestyles, exercise and new technologies. Chapter 3 debates psychological and cognitive issues in aging and finally in Chapter 4, an older people self assessment is proposed and the role of communities and supporters are highlighted. We think that real social and health care integration at community level could be the key point to deliver effective health promotion and preventive intervention. Enjoy the reading!

Geriatrics. --- Older people --- Health and hygiene. --- preventing disability --- dietary intake --- Active aging --- chronic diseases --- Life styles --- Mental Health --- Disease Management --- New technologies --- Elderly --- physical activity

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Azoospermia, defined as the absence of sperm in the ejaculate after examination of the centrifuged specimens, affects about 1% of the male population and 10–15% of infertile men. In about two-thirds of cases, this is caused by severe spermatogenic dysfunction, and it is commonly termed “nonobstructive azoospermia” (NOA) to differentiate it from the less severe form of azoospermia caused by the obstruction of the seminal tract (obstructive azoospermia—OA), the latter affecting the remaining one-third of cases. Managing patients with NOA is challenging due to the severity of spermatogenic dysfunction and the lack of medical treatments, with surgical retrieval of testicular sperm being the only way of enabling some of these patients to father their own biological children. In-depth clinical knowledge is key for supporting clinical reasoning and decision making when counselling patients with NOA, and surgical skill is required to maximize the outcome of surgical procedures that aim to retrieve testicular sperm. The present book is a collection of scientific papers published in a Special Issue of the Journal of Clinical Medicine, authored by some of the most influential researchers in the field. The Special Issue, and thus also this book, were conceived to provide early career reproductive urologists and endocrinologists with an update of the scientific evidence in the field, together with surgical tips.

nonobstructive azoospermia --- micro-TESE --- FSH treatment --- hormonal treatment --- testosterone level --- microdissection testicular sperm extraction --- non-obstructive azoospermia --- management --- infertility --- intracytoplasmic sperm injection --- testicular azoospermia --- sperm selection --- sperm --- cryopreservation --- in vitro maturation --- azoospermia --- diagnosis --- male infertility --- spermatogenic failure --- testis biopsy --- sperm retrieval --- genetic testing --- endocrine evaluation --- review --- hypogonadism --- Sertoli cell-only syndrome --- testicular spermatozoa --- processing --- microfluidics --- new technologies --- genetics --- exome --- WES --- Y chromosome --- cancer --- NOA --- genes --- general health --- ICSI --- offspring health --- microTESE --- prediction model --- n/a

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In der gegenwärtigen digitalen Transformation wird auch die Büroarbeit komplett neu organisiert. Eine zentrale Rolle spielen dabei Konzepte wie »Lean Production« und »agile Methoden«. Das Buch zeigt die Folgen dieser Entwicklung für die Arbeitswelt von Angestellten anhand von Fallstudien aus den Bereichen Software-Entwicklung, Maschinenbau, Metall- und Elektroindustrie. Erkennbar wird ein grundlegender Umbruch in der Angestelltenarbeit mit ungewissem Ausgang. Kommt die Büroarbeit am digitalen Fließband oder ein Aufbruch in eine neue Humanisierung der Arbeitswelt? Das Buch liefert Antworten auf diese Fragen und zeigt: Das Ergebnis der Entwicklung hängt von unserer bewussten Gestaltung ab. »Der Band besticht durch die sorgfältige Analyse von sechs Fallstudien und ein avanciertes theoretisches Konzept.« WSI Mitteilungen, 72/6 (2019) »Erhellend und lesenswert.« Annette Jensen, Mitbestimmung, 01.03.2018 Besprochen in: http://www.labournet.de, 14.03.2018 RKW Bücherdienst, 1 (2018) OrganisationsEntwicklung, 3 (2018)

Agile Methoden. --- Agile Methods. --- Angestelltenarbeit. --- Arbeit. --- Arbeits- und Industriesoziologie. --- Arbeitsökonomie. --- Digital Transformation. --- Digitale Transformation. --- Digitalisierung. --- Digitalization. --- Gesellschaft. --- Industrialisation. --- Industrialisierung. --- Labour Economics. --- Lean Production. --- Organisationssoziologie. --- Society. --- Sociology of Organizations. --- Sociology of Technology. --- Sociology of Work and Industry. --- Sociology. --- Soziologie. --- Techniksoziologie. --- White-collar-work. --- Work. --- SOCIAL SCIENCE / Sociology / General. --- Informatisierung; Industrialisierung; Digitalisierung; Lean Production; Agile Methoden; Angestelltenarbeit; Digitale Transformation; Arbeit; Gesellschaft; Arbeits- und Industriesoziologie; Organisationssoziologie; Techniksoziologie; Arbeitsökonomie; Soziologie; New Technologies; Industrialisation; Digitalization; Agile Methods; White-collar-work; Digital Transformation; Work; Society; Sociology of Work and Industry; Sociology of Organizations; Sociology of Technology; Labour Economics; Sociology