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Book
Materials and Life Science Experimental Facility (MLF) at the Japan Proton Accelerator Research Complex (J‑PARC)
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ISBN: 3038974846 3038974838 Year: 2019 Publisher: MDPI - Multidisciplinary Digital Publishing Institute

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The Materials and Life Science Experimental Facility (MLF) at the Japan Proton Accelerator Research Complex (J-PARC) is a landmark large user-facility producing neutron and muon beams. Those beams feed over 20 beamlines hosting world-class instruments for the investigation of matter across the disciplines of materials science, solid state physics and chemistry, biological and life sciences, geology, engineering, and their wider applications. Neutron and muons can probe matter in very peculiar ways. They are sensitive to magnetism and hydrogen atoms, can penetrate materials deeply or probe surfaces, and allow one to investigate the fundamental dynamics of the materials. In the past three to four decades, neutron scattering has largely contributed to the development of modern technology, such as computers, mobile phone technology, electo-chemistry, the transportation industry, and the pharmaceutic industry. MLF is a world leader in such characterization technology and serves yearly to about 700 research experiments conducted from users of 34 countries around the world. The present book describes technical details of the proton accelerator, the neutron spallation source, the muon facility, and all the beamlines with engineering realization, specifications, and relevant examples.


Book
Recent Advances in Small-Angle Neutron Scattering
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Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Over the decades, small-angle neutron scattering has became a definitive method for structural investigation on the mesoscale between a few Angstrom up to a few 100 nm. This makes it an indispensable tool for non-destructive material investigations in fields ranging from chemistry and biology, over material sciences to solid state physics, especially taking into account the fundamental nature of neutrons, which makes it possible to probe different isotopes and, therefore, enhance contrast by choosing an appropriate isotope distribution or to probe the spin state of the investigated materials. This Special Issue is dedicated to elucidate the advances made with SANS over the last few years, which includes new instrumentation, sample environment and experimental control, as well as novel approaches and experimental techniques. The ideas and approaches collected here will serve both the experienced experimenter as well as the novice to appraise whether their specific experimental setup is feasible with new ideas.


Book
Nucleic Acid Architectures for Therapeutics, Diagnostics, Devices and Materials
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ISBN: 3039212605 3039212591 Year: 2019 Publisher: MDPI - Multidisciplinary Digital Publishing Institute

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Nucleic acids (RNA and DNA) and their chemical analogs have been utilized as building materials due to their biocompatibility and programmability. RNA, which naturally possesses a wide range of different functions, is now being widely investigated for its role as a responsive biomaterial which dynamically reacts to changes in the surrounding environment. It is now evident that artificially designed self-assembling RNAs, that can form programmable nanoparticles and supra-assemblies, will play an increasingly important part in a diverse range of applications, such as macromolecular therapies, drug delivery systems, biosensing, tissue engineering, programmable scaffolds for material organization, logic gates, and soft actuators, to name but a few. The current exciting Special Issue comprises research highlights, short communications, research articles, and reviews that all bring together the leading scientists who are exploring a wide range of the fundamental properties of RNA and DNA nanoassemblies suitable for biomedical applications.


Book
Ionic Conductive Membranes for Fuel Cells
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Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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This book, titled “Ionic Conductive Membranes for Fuel Cells”, from the journal Membranes, discusses the state of the art and future developments in the field of polymer electrolyte membranes for fuel cells, an efficient and clean system for converting fuel into energy.


Book
Cholinesterase Research
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Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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This collection of 10 papers includes original as well as review articles focused on the cholinesterase structural aspects, drug design and development of novel cholinesterase ligands, but also contains papers focused on the natural compounds and their effect on the cholinergic system and unexplored effects of donepezil.


Book
Molecular Magnets
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Year: 2019 Publisher: MDPI - Multidisciplinary Digital Publishing Institute

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Molecular magnets show many properties not met in conventional metallic magnetic materials, i.e. low density, transparency to electromagnetic radiation, sensitivity to external stimuli such as light, pressure, temperature, chemical modification or magnetic/electric fields, and others. They can serve as “functional” materials in sensors of different types or be applied in high-density magnetic storage or nanoscale devices. Research into molecule-based materials became more intense at the end of the 20th century and is now an important branch of modern science. The articles in this Special Issue, written by physicists and chemists, reflect the current work on molecular magnets being carried out in several research centers. Theoretical papers in the issue concern the influence of spin anisotropy in the low dimensional lattice of the resulting type of magnet, as well as thermodynamics and magnetic excitations in spin trimers. The impact of external pressure on structural and magnetic properties and its underlying mechanisms is described using the example of Prussian blue analogue data. The other functionality discussed is the magnetocaloric effect, investigated in coordination polymers and high spin clusters. In this issue, new molecular magnets are presented: (i) ferromagnetic high-spin [Mn6] single-molecule magnets, (ii) solvatomagnetic compounds changing their structure and magnetism dependent on water content, and (iii) a family of purely organic magnetic materials. Finally, an advanced calorimetric study of anisotropy in magnetic molecular superconductors is reviewed.


Book
Modeling and Simulation of Lipid Membranes
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Year: 2022 Publisher: Basel MDPI Books

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Cell membranes are complex structures able to contain the main elements of the cell and to protect them from the external surroundings, becoming the most fundamental interface in Biology. The main subject of this book is the study of the structure and characteristics of lipid membranes in a wide variety of environments, ranging from simple phospholipid membranes to complex systems including proteins, peptides, or oncogenes as well as the analysis of the interactions of the membrane components with small molecules and drugs. The scope of this book is to provide recent developments on membrane structure, composition and function by means of theoretical and experimental techniques, some of them combining computer simulations with available data obtained at the laboratory.This Special Issue aims to report brand new key contributions to the field and also to give an overview about the connection between experiments and computer simulations, addressing fundamental aspects and applied research in biological membranes, with particular attention paid to the applications of computer modeling and simulation to medicine.


Book
Advances in Topological Materials
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Year: 2022 Publisher: MDPI - Multidisciplinary Digital Publishing Institute

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The present collection of articles focuses on different aspects of topological-materials studies. Recent progress in both, theoretical and experimental, studies is covered in this Special Issue. A particular stress is given on different optical investigations, as well as on recent band-structure calculations. Besides, neutron scattering experiments, crystal growth, and a number of theoretical models for different topological systems are discussed.


Book
Creep and High Temperature Deformation of Metals and Alloys
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ISBN: 3039218794 3039218786 Year: 2019 Publisher: MDPI - Multidisciplinary Digital Publishing Institute

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By the late 1940s, and since then, the continuous development of dislocation theories have provided the basis for correlating the macroscopic time-dependent deformation of metals and alloys—known as creep—to the time-dependent processes taking place within the metals and alloys. High-temperature deformation and stress relaxation effects have also been explained and modeled on similar bases. The knowledge of high-temperature deformation as well as its modeling in conventional or unconventional situations is becoming clearer year by year, with new contemporary and better performing high-temperature materials being constantly produced and investigated.This book includes recent contributions covering relevant topics and materials in the field in an innovative way. In the first section, contributions are related to the general description of creep deformation, damage, and ductility, while in the second section, innovative testing techniques of creep deformation are presented. The third section deals with creep in the presence of complex loading/temperature changes and environmental effects, while the last section focuses on material microstructure–creep correlations for specific material classes. The quality and potential of specific materials and microstructures, testing conditions, and modeling as addressed by specific contributions will surely inspire scientists and technicians in their own innovative approaches and studies on creep and high-temperature deformation.


Book
Intramolecular Hydrogen Bonding 2021
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Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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This book describes the results of both theoretical and experimental research on many topical issues in intramolecular hydrogen bonding. Its great advantage is that the presented research results have been obtained using many different techniques. Therefore, it is an excellent review of these methods, while showing their applicability to the current scientific issues regarding intramolecular hydrogen bonds. The experimental techniques used include X-ray diffraction, infrared and Raman spectroscopy (IR), nuclear magnetic resonance spectroscopy (NMR), nuclear quadrupole resonance spectroscopy (NQR), incoherent inelastic neutron scattering (IINS), and differential scanning calorimetry (DSC). The solvatochromic and luminescent studies are also described. On the other hand, theoretical research is based on ab initio calculations and the Car–Parrinello Molecular Dynamics (CPMD). In the latter case, a description of nuclear quantum effects (NQE) is also possible. This book also demonstrates the use of theoretical methods such as Quantum Theory of Atoms in Molecules (QTAIM), Interacting Quantum Atoms (IQA), Natural Bond Orbital (NBO), Non-Covalent Interactions (NCI) index, Molecular Tailoring Approach (MTA), and many others.

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