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Excitatory amino acids : clinical results with antagonists
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ISBN: 9780125468206 0125468202 9780080531342 0080531342 9786611033484 1281033480 Year: 1997 Publisher: San Diego, Calif. : Academic Press,

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Abstract

Glutamate is the major excitatory neurotransmitter in the brain and dysfunction of glutamate transmission is the likely cause of a variety of diseases including neurodegeneration following cerebral ischemia, Huntington's chorea, amyotrophic lateral sclerosis, epilepsy, spasticity, emesis, chronic pain, and schizophrenia. Excitatory amino acid receptor agonists and antagonists are therefore of major interest as potential drugs for central nervous system disorders. Excitatory Amino Acids is the first book entirely dedicated to the results of human testing of modulators of excitatory amino

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