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Sickle cell anemia --- Drepanocytic anemia --- Meniscocytosis --- Sickle cell disease --- Blood hyperviscosity syndrome --- Hemoglobinopathy --- Hemolytic anemia --- Treatment.

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Sickle cell anemia. --- Hemolytic anemia. --- Anemia --- Hemolysis and hemolysins --- Drepanocytic anemia --- Meniscocytosis --- Sickle cell disease --- Blood hyperviscosity syndrome --- Hemoglobinopathy --- Hemolytic anemia

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This practical clinical handbook reveals that sickle cell disease (SCD) is an increasingly common condition to manage in Europe and North America. SCD demands clinical expertise and experience as well as sensitivity to its social and cultural context. This book is designed to broaden readers’ knowledge in this challenging condition by describing the acute and long-term complications unique to SCD and that affect nearly every system of the body. Critically, it also details the significant recent advances in understanding the pathophysiology of SCD that are leading to novel treatment modalities. Sickle Cell Disease in Clinical Practice promotes higher quality care by outlining the clinical problems as they arise, and covering essential background information, including up-to-date research, and useful points to guide management. As such, the intended target audience is broad and includes general physicians, general practitioners, hematologists, pediatricians, emergency medicine physicians, surgeons, medical students, nurse specialists and commissioners.

Medicine & Public Health. --- Hematology. --- Pathology. --- Blood Transfusion Medicine. --- Medicine. --- Blood transfusion. --- Médecine --- Hématologie --- Pathologie --- Medicine --- Health & Biological Sciences --- Pathology --- Sickle cell anemia. --- Clinical medicine. --- Medicine, Clinical --- Drepanocytic anemia --- Meniscocytosis --- Sickle cell disease --- Blood hyperviscosity syndrome --- Hemoglobinopathy --- Hemolytic anemia --- Blood transfusion --- Blood transfusion therapy --- Hemotherapy --- Transfusion medicine --- Transfusion of blood --- Transfusion therapy --- Transfusion therapy, Blood --- Surgery --- Blood banks --- Blood groups --- Hospitals --- Transfusion-free surgery --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine, Preventive --- Haematology --- Internal medicine --- Blood --- Transfusion committees

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This book is a wide-ranging guide to the diagnosis and management of the numerous medical and surgical complications that may arise in patients with sickle cell anemia. After introductory chapters on the genetics, pathophysiology, clinical features, and variants of sickle cell anemia, the complications observed in different parts of the body are addressed in a series of well-illustrated chapters. The coverage includes splenic, hepatobiliary, musculoskeletal, gastrointestinal, ophthalmological, cardio- and cerebrovascular, and renal complications, as well as acute chest syndrome, leg ulcers, hand and foot syndrome, acute appendicitis, and priapism. Treatment-oriented chapters consider perioperative management, blood transfusion therapy, hydroxyurea treatment, hematopoietic stem cell transplantation, and emerging strategies. The book is clearly written in a distinctive bullet point format for ease of reference and emphasizes especially aspects of practical significance. It will be of value for hematologists, general surgeons, internists, pediatricians, pediatric surgeons, fellows, residents, medical students, and nurses.

Anemia, Sickle Cell --- History, 20th Century --- Anemia, Hemolytic, Congenital --- History, Modern 1601 --- -Hemoglobinopathies --- Genetic Diseases, Inborn --- History --- Hematologic Diseases --- Anemia, Hemolytic --- Anemia --- Congenital, Hereditary, and Neonatal Diseases and Abnormalities --- Hemic and Lymphatic Diseases --- Humanities --- Diseases --- Pathology --- Medicine --- Health & Biological Sciences --- Sickle cell anemia --- Complications. --- Drepanocytic anemia --- Meniscocytosis --- Sickle cell disease --- Blood hyperviscosity syndrome --- Hemoglobinopathy --- Hemolytic anemia --- Hematology. --- Surgery. --- Biochemistry. --- Pediatric Surgery. --- Medical Biochemistry. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Surgery, Primitive --- Haematology --- Internal medicine --- Blood --- Composition --- Pediatric surgery. --- Medical biochemistry. --- Pediatric surgery --- Surgery, Pediatric --- Children --- Medical biochemistry --- Pathobiochemistry --- Pathological biochemistry --- Biochemistry --- Treatment

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In the 1980's, a research team led by Parisian scientists identified several unique DNA sequences, or haplotypes, linked to sickle cell anemia in African populations. After casual observations of how patients managed this painful blood disorder, the researchers in question postulated that the Senegalese type was less severe. The Enculturated Gene traces how this genetic discourse has blotted from view the roles that Senegalese patients and doctors have played in making sickle cell ""mild"" in a social setting where public health priorities and economic austerity programs have forced people to

Kinship --- Genetic disorders --- Sickle cell anemia --- Ethnology --- Clans --- Consanguinity --- Families --- Kin recognition --- Congenital diseases --- Disorders, Genetic --- Disorders, Inherited --- Genetic diseases --- Hereditary diseases --- Inherited diseases --- Diseases --- Medical genetics --- Drepanocytic anemia --- Meniscocytosis --- Sickle cell disease --- Blood hyperviscosity syndrome --- Hemoglobinopathy --- Hemolytic anemia --- Health aspects --- Social aspects --- Patients --- Services for --- Genetic aspects. --- Africa. --- African anthropology. --- African genetics. --- African sicklers. --- Albert Royer Children's Hospital. --- CNTS. --- Centre nationale de transfusion sanguine. --- DNA haplotypes. --- DNA sequences. --- HbAS. --- International Organization for the Fight against Sickle Cell. --- National Blood Transfusion Center. --- OILD. --- RFLP. --- Restriction Fragment Length Polymorphism. --- Senegal. --- Senegalese attitudes. --- Senegalese sickle cell. --- alternative care. --- biological expressions. --- biosocial politics. --- culture. --- disease experiences. --- disease expression. --- economic austerity. --- economically triaged care. --- ethnic population purity. --- fagara. --- genetic difference. --- genetic sequence. --- geneticists. --- global health problems. --- global health. --- healing practices. --- health intervention. --- health. --- healthy sicklers. --- heterozygous sickle cell. --- low-tech strategy. --- multilateral institutions. --- normalization techniques. --- patient advocacy. --- political apathy. --- population. --- public health. --- public neglect. --- self-care. --- sickle cell DNA markers. --- sickle cell anemia. --- sickle cell gene. --- sickle cell research. --- sickle cell trait. --- sicklers. --- social networks. --- traditional plants. --- vitality.