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Brain metastases are the most dreaded complication of systemic cancer, affecting approximately 170,000 people a year, a far greater incidence than primary brain tumors. Advances in modern chemotherapy have led to an improved control of system cancers, often with agents that poorly penetrate the central nervous system, resulting in an increasing incidence of brain metastases. Traditional chemotherapy has had little impact on brain metastases. The main therapeutic option is radiation therapy, and in a small number of patients - surgery. However, refinements in all of these treatments offer some positive outcomes and an increased ability to stratify patients based on certain criteria. This book will bring current information on the presentation and management of patients with brain metastases, providing available data, giving guidelines that can be applied in day to day practice, updated information for neuro-surgeons, radiation oncologists, medical oncologists, and neuro-oncologists, as well as an overview for physicians in training. "Brain metastases are one of the most devasting consequences of cancer. This text addresses the epidemiology, pathophysiology, imaging, and management of this complication. Experts in the field cover a broad array of relevant topics highlighting the challenges and current therapeutic strategies." Steven T. Rosen, M.D. Series Editor.

Brain --- Metastasis. --- Cancer. --- Cancer --- Cancer metastasis --- Dissemination of cancer --- Metastases --- Metastatic cancer --- Neoplasm metastasis --- Spread of cancer --- Tumor dissemination --- Tumor metastasis --- Tumor spread --- Pathology --- Cancer invasiveness --- Cancer of unknown primary origin --- Dissemination --- Metastasis --- Oncology  . --- Surgical oncology. --- Neurosurgery. --- Oncology. --- Surgical Oncology. --- Nerves --- Neurosurgery --- Oncologic surgery --- Oncological surgery --- Surgical oncology --- Tumors --- Surgery --- Excision --- Treatment --- Nervous system --- Cancer Therapy. --- Treatment. --- Surgery. --- Cancer therapy --- Cancer treatment --- Therapy --- Brain Neoplasms --- Cerveau --- Métastases --- secondary. --- EPUB-LIV-FT LIVMEDEC LIVSANTE SPRINGER-B

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Written by internationally recognized experts, The Genetics of Cancer provides up-to-date information and insight into the genetic basis of cancer and the mechanisms involved in cancer invasion and its secondary spread. This volume presents the deregulation of the cell cycle in tumor development and integrates the function of tumor suppressor genes, oncogenes, and metastasis-associated genes in the pathogenesis and progression of cancer. The Genetics of Cancer will be useful to all graduate students, clinicians, and researchers working in the fields of cancer biology, genetics, a

Neoplasm Metastasis --- Neoplasm Invasiveness --- Cell Transformation, Neoplastic --- Neovascularization, Pathologic --- Oncogenes --- Cancer --- Metastasis. --- Cancer invasiveness. --- Métastases --- genetics. --- Genetic aspects. --- Aspect génétique --- Caractère envahissant --- immunology. --- Métastases --- Aspect génétique --- Caractère envahissant --- ELSEVIER-B EPUB-LIV-FT --- Cancer invasiveness --- Metastasis --- Cancer genetics --- Cancer genes --- Dissemination of cancer --- Invasiveness (Oncology) --- Neoplasm invasiveness --- Spread of cancer --- Tumor dissemination --- Tumor invasiveness --- Tumor progression --- Tumor spread --- Cancer cells --- Cancer metastasis --- Metastases --- Metastatic cancer --- Neoplasm metastasis --- Tumor metastasis --- Pathology --- Cancer of unknown primary origin --- Genetic aspects --- genetics --- immunology --- Growth --- Dissemination