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Book
Statistical approaches to gene x environment interactions for complex phenotypes
Author:
ISBN: 0262335522 9780262335522 9780262335539 0262335530 9780262034685 0262034689 0262335514 Year: 2016 Publisher: Cambridge, Massachusetts ; London, England : The MIT Press,

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Findings from the Human Genome Project and from Genome-Wide Association (GWA) studies indicate that many diseases and traits manifest a more complex genomic pattern than previously assumed. These findings, and advances in high-throughput sequencing, suggest that there are many sources of influence-genetic, epigenetic, and environmental. This volume investigates the role of the interactions of genes and environment (G x E) in diseases and traits (referred to by the contributors as complex phenotypes) including depression, diabetes, obesity, and substance use.


Book
Does your family make you smarter? : nature, nurture, and human autonomy
Author:
ISBN: 9781316604465 1316604462 9781107150058 1107150051 1316595374 1316595234 131659551X 131659565X 1316576698 1316596214 1316594394 9781316595657 9781316596210 9781316576694 Year: 2016 Publisher: Cambridge : Cambridge University Press,

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Does your family make you smarter? James R. Flynn presents an exciting new method for estimating the effects of family on a range of cognitive abilities. Rather than using twin and adoption studies, he analyses IQ tables that have been hidden in manuals over the last 65 years, and shows that family environment can confer a significant advantage or disadvantage to your level of intelligence. Wading into the nature vs. nurture debate, Flynn banishes the pessimistic notion that by the age of seventeen, people's cognitive abilities are solely determined by their genes. He argues that intelligence is also influenced by human autonomy - genetics and family notwithstanding, we all have the capacity to choose to enhance our cognitive performance. He concludes by reconciling this new understanding of individual differences with his earlier research on intergenerational trends (the 'Flynn effect') culminating in a general theory of intelligence.


Multi
S’entreprendre avec ses gènes : Enquête sur l’auto-génétisation
Author:
ISSN: 12698644 ISBN: 9782753573970 2753573972 2753585415 Year: 2021 Publisher: Rennes : Presses universitaires de Rennes,

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Depuis le lancement du programme de séquençage du génome humain, le développement continu des technologies et des langages génétiques a fait émerger une riche littérature au croisement de la sociologie, de l’anthropologie et de la philosophie s’interrogeant sur la place grandissante acquise par le gène dans nos sociétés. Si la notion de génétisation s’y est imposée comme schème interprétatif critique des processus en jeu, celle-ci se voit aujourd’hui en partie dépassée consécutivement au développement de nouvelles modalités de diffusion des technologies génétiques. L’apparition d’une offre d’autotests génétiques par le biais d’Internet laisse en effet apparaître une autonomisation de la dynamique de génétisation au sein de la société, soit l’émergence d’une auto-génétisation à l’heure où la génomique en vient à se pratiquer en version Do-It-Yourself. Sur la base d’une enquête par observations ethnographiques de divers espaces numériques et d’entretiens, il ressort que des publics grandissants se voient désormais acquis à l’intérêt qu’il y aurait à s’orienter vers les gènes pour pouvoir se constituer un « capital santé » ou un « capital généalogique ». Au cœur de cette dynamique où le génétique en vient à englober des domaines en expansion, touchant tout autant à la santé qu’à la construction de l’identité, la génétisation n’apparaît plus seulement comme une opération de nature intellectuelle conduisant à valoriser le rôle des gènes face aux facteurs dits d’environnement, mais aussi et surtout comme une entreprise pratique au cours de laquelle l’individu en vient à se tourner vers ses gènes pour faire face à un environnement devenu incertain.


Book
Mismatch
Authors: ---
ISBN: 1429470038 0191513121 128075317X 1281770027 9786611770020 0191551767 9780191513121 Year: 2008 Publisher: Oxford New York Oxford University Press

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Our modern lifestyles, city-bound with abundant nutrition - are far removed from the hunter-gatherer lifestyles of our ancestors. However we have not evolved to reflect this change. This fascinating and controversial book explores whether it is this 'mismatch' that has led to the deadly explosion in lifestyle diseases we face today. - ;We have built a world that no longer fits our bodies. Our genes - selected through our evolution - and the many processes by which our development is tuned within the womb, limit our capacity to adapt to the modern urban lifestyle. There is a mismatch. We are se

On human nature
Author:
ISBN: 0674076540 9780674076549 0674016386 9780674016385 Year: 2004 Publisher: Cambridge, Mass. : Harvard University Press,

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In his new preface E. O. Wilson reflects on how he came to write this book: how The Insect Societies led him to write Sociobiology, and how the political and religious uproar that engulfed that book persuaded him to write another book that would better explain the relevance of biology to the understanding of human behavior.


Book
Environmental Epigenomics in Health and Disease : Epigenetics and Disease Origins
Authors: ---
ISBN: 3642427286 3642233791 3642233805 Year: 2013 Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer,

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Exposure to environmental toxicants is associated with changes in DNA methylation and gene expression profiles that together can contribute to increased disease susceptibility. The chapters in this volume, Environmental Epigenomics in Health and Disease - Epigenetics and Disease Origins, address a wide range of environmental exposures, such as airborne particulates, cocaine, radiation, tobacco smoke, and xenoestrogens. Particular emphasis is placed on the consequences of environmental exposures during development on epigenetic reprogramming that influences adult disease pathogenesis. Health outcomes associated with these exposures include autoimmune disorders, neurodevelopmental disorders, and cancer. Importantly, dietary supplements and drugs can modify the epigenetic effects induced by these agents, thereby reducing their toxicological impact. The overall purpose of this volume and its companion, Environmental Epigenomics in Health and Disease - Epigenetics and Complex Diseases, is to give readers an overview of how environmental exposures during early development can influence disease formation by disrupting epigenetic processes and developmental programming.


Book
Challenging genetic determinism : new perspectives on the gene in its multiple environments
Authors: --- ---
ISBN: 1283529211 9786613841667 0773586547 9780773586543 9780773537804 0773537805 9780773538139 0773538135 9781283529211 6613841668 Year: 2011 Publisher: Montreal ; Ithaca, N.Y. : McGill-Queen's University Press,


Periodical
Genescreen : an international journal of medical genomics.
ISSN: 1466920X 14669218 Year: 2000 Publisher: [Oxford, England] : Blackwell Science,

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Keywords

Genetics --- Genetics, Medical --- Genetic Predisposition to Disease --- Genetic Screening --- Genome --- Medical genetics --- Genomics --- Génétique médicale --- Génomique --- Periodicals. --- Périodiques --- Genomes --- Human genome --- Genetics, Medical. --- Genome. --- Genetic Testing. --- Genetic Predisposition to Disease. --- Genomes. --- Human genome. --- Medical genetics. --- Chemistry --- Health Sciences --- Life Sciences --- Biochemistry --- Pathology --- Predisposition, Genetic --- Susceptibility, Genetic --- Genetic Predisposition --- Genetic Susceptibility --- Genetic Predispositions --- Genetic Susceptibilities --- Predispositions, Genetic --- Susceptibilities, Genetic --- Disease Susceptibility --- Predictive Genetic Testing --- Predictive Testing, Genetic --- Testing, Genetic Predisposition --- Genetic Predisposition Testing --- Genetic Predictive Testing --- Genetic Screenings --- Genetic Testing, Predictive --- Predisposition Testing, Genetic --- Screening, Genetic --- Screenings, Genetic --- Testing, Genetic --- Testing, Genetic Predictive --- Testing, Predictive Genetic --- Human Genetics --- Medical Genetics --- Genetics, Human --- genetics --- diagnosis --- Genetic Testing --- Anticipation, Genetic --- Genetic Association Studies --- Gene-Environment Interaction --- Prenatal Diagnosis --- Preimplantation Diagnosis --- Cytogenetic Analysis --- Molecular Diagnostic Techniques --- Databases, Genetic --- Databases, Nucleic Acid --- Genetic Privacy --- Genes --- Proteome --- Anthropology, Physical --- Chromosome Disorders --- Sex Chromosome Disorders --- Genetic Diseases, Inborn --- Molecular Medicine --- Human chromosomes --- Haploidy --- Clinical genetics --- Diseases --- Heredity of disease --- Human genetics --- Medical sciences --- Genetic disorders --- Genetic aspects


Book
Gene-Environment Interplay in Interpersonal Relationships across the Lifespan
Authors: ---
ISBN: 9781493929238 1493929224 9781493929221 1493929232 Year: 2015 Publisher: New York, NY : Springer New York : Imprint: Springer,

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Intriguing new findings on how genes and environments work together through different stages of life take the spotlight in this significant collection. Studies from infancy to late adulthood show both forces as shaping individuals' relationships within family and non-family contexts, and examine how these relationships, in turn, continue to shape the individual. Transitional periods, in which individuals become more autonomous and relationships and personal identities become more complicated, receive special emphasis. In addition, chapters shed light on the extent to which the quantity and quality of genetic and environmental influence may shift across and even within life stages.   Included in the coverage:   Gene-environment interplay in parenting young children. The sibling relationship as a source of shared environment. Gene-environment transactions in childhood and adolescent problematic peer relationships. Toward a developmentally sensitive and genetically informed perspective on popularity. Spouse, parent, and co-worker: roles and relationships in adulthood. The family system as a unit of clinical care: the role of genetic systems.   Behavioral geneticists, clinical psychologists, and family therapists will find in Gene-Environment Interplay in Interpersonal Relationships across the Lifespan a window into current thinking on the subject, new perspectives for understanding clients and cases, and ideas for further study.

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