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DNA viruses: a practical approach
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ISBN: 1280375647 9786610375646 0585484112 9780585484112 661037564X 0199637180 9780199637188 0199637199 9780199637195 Year: 1999 Publisher: Oxford Oxford University Press

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Abstract

DNA Viruses: A Practical Approach groups together the major experimental methods currently employed to study DNA viruses, from the fundamentals of virus culture to novel techniques such as surface plasmon resonance spectrometry and realtime PCR analysis of drug resistance mutations in clinical isolates. Chapter 1 provides an overview of the extraction, purification and characterizations of virus DNA, but also covers the fundamentals of DNA virus culture. Chapters 2 and 3 describe approaches to the molecular investigation and mutagenesis of DNA virus genomes. Chapter 4 considers DNA virus replication and then chapters 5 & 6 describe methods to study transcription control. Chapters 7 to 9 consider aspects of the pathogenesis of DNA virus infections. The final chapter describes the current technology being applied to the development of DNA virus vectors for gene delivery. This volume will therefore be of interest to all those working on DNA viruses whether in academia, industry or clinical research.


Book
Human papillomavirus infections : from laboratory to clinical practice
Author:
ISSN: 20500289 ISBN: 1908818174 1907568743 9781908818171 9781907568749 Year: 2012 Volume: no. 14 Publisher: Cambridge : Woodhead Pub.,

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Human papillomavirus (HPV) is one of the most common causes of sexually transmitted diseases worldwide, both in men and women. This book provides the scientific background needed to understand the natural history and pathogenesis of HPV infection and offers discussion of its clinical features, diagnosis, treatment and prevention. It begins with chapters covering the epidemiology, virology, history and transmission of the infection, as well as its pathogenesis and clinical features. Following a discussion of the relationship between HPV and cancer, chapters in the second half of the book look at diagnosis, testing and treatment. The book concludes with detailed coverage of the prevention of HPV through worldwide vaccination programmes.


Book
Adenovirus epithelial keratitis and Thygeson's superficial punctate keratitis : in vivo morphology in the human cornea
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ISBN: 3642216331 9786613449566 1283449560 364221634X Year: 2012 Publisher: New York : Springer,

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Adenovirus epithelial keratitis and Thygeson's superficial punctate keratitis (TSPK) are apparently disparate diseases. While adenovirus eye infections are very common, caused by a known agent, and highly infectious, TSPK is comparatively rare, of unknown causation, and seemingly non-contagious. Despite these differences, the two diseases are often confused in clinical practice owing to the similarity between adenovirus epithelial infiltrates and ‘coarse’ epithelial TSPK lesions. This book presents the morphological features, dynamics, and sequelae of adenovirus and Thygeson's keratitides captured at high magnification in the living human cornea. It thereby fills the existing void between conventional photographs and slit-lamp observations. Case reports demonstrate the importance of patient history in differential diagnosis, illustrate the need for familiarity with early manifestations of adenovirus infections, and assist in the diagnosis of rare variants of TSPK. Furthermore, the detailed observations on the natural course of the diseases ensure that the book will serve not only as a diagnostic tool but also as a reference when evaluating the effects of potential new treatments.


Book
The challenge of highly pathogenic microorganisms : mechanisms of virulence and novel medical countermeasures
Authors: --- --- ---
ISBN: 940079911X 9048190533 9786612925115 1282925113 9048190541 Year: 2010 Publisher: New York : Springer,

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This book addresses the unique features of four microorganisms that constitute the top bioterror threat agents: Bacillus anthracis; Yersinia pestis, Francisella tularensis and Orthopoxviruses. Side-by-side updated information about their pathogenisis, virulence and epidemiology is provided in a single volume, allowing for evaluation of common features as well as common strategies for defense. Classical microbiological as well as genomic, proteomic & transcriptomic approaches towards development of strategies of novel prophylactic and post-exposure treatment and related aspects of diagnostics and bioforensics are covered. Written by top scientists, this book will be of major interest to all researchers interested in the intricate biology of highly pathogenic microorganisms, to scientists and clinicians interested in microbial pathogenesis and prevention, and to a wide range of professionals dealing with the various aspects of bio-defense.

Assessment of future scientific needs for live variola virus
Author:
ISBN: 0309064414 9786610185993 1280185996 030959698X 0585068003 9780585068008 9780309064415 0309173191 Year: 1999 Publisher: Washington, D.C. National Academy Press

Frontiers in viral hepatitis
Authors: --- ---
ISBN: 9780444509864 0444509860 Year: 2003 Publisher: [Place of publication not identified] Elsevier

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Frontiers in Viral Hepatitis provides a compilation of the research from over 40 key opinion leaders in the field of Hepatitis. The book focuses on the latest advances in the search for new, more effective therapeutic options and related topics in viral hepatitis. These include regulatory issues, epidemiology, and emerging viruses; immunology and vaccines; viral hepatitis B and C infections in children; genetics pathology and viral diagnosis; cell systems and animal models; novel therapeutics for hepatitis B and C; resistance and therapeutic strategies in humans; and prevention and treatment options for hepatocellular carcinoma. The breadth of information published in this volume provides insight into current prevention and treatment options. Recent advances in our understanding of the molecular biology, immunology and pathogenesis of hepatitis viruses have accelerated at a remarkable rate, offering a more comprehensive perspective on hepatitis.


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Burkitt's lymphoma
Author:
ISBN: 1461443121 1489988718 146144313X 1283933608 Year: 2013 Publisher: New York : Springer,

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This volume aims to bring together efforts with a patient-oriented focus from physicians to diagnostics and clinical implications of the disease as mostly seen in the equatorial African setting. However, the chapters cover the breadth of studies on Burkitt’s lymphoma with some clues for the potential future of Burkitt’s lymphoma research that can have therapeutic benefits for patients.    This text explore a range of topics associated with Burkitt’s lymphoma, including molecular biology, diagnosis, its association with AIDS and Malaria, immune responses, therapeutic approaches and a unique view from the bedside. This volume is comprehensive and unique and represents the most up-to-date clinical and research activities on Burkitt’s lymphoma.

Marek's disease
Authors: --- ---
ISBN: 0120883791 9786611008055 1281008052 0080479189 9780120883790 142374246X 9781423742463 9780080479187 9781281008053 6611008055 Year: 2004 Publisher: Amsterdam Boston Elsevier

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Marek's disease is a form of cancer of poultry caused by an important herpesvirus (MDV). It continues to be a threat to poultry health and welfare and worldwide losses are estimated to be US 1 billion annually. This book provides a timely review of the problems of Marek's disease with descriptions of the complex viral life cycle, how MDV targets different types of white blood cells, and details of the virus structure, its genes and proteins.* The multiplicity of factors contributing to susceptibility is explored in detail* Vaccination - the problems arising from current vaccinatio


Book
Human papillomavirus : a practical guide for urologists
Authors: ---
ISBN: 3540709738 9786612655890 1282655892 3540709746 Year: 2009 Publisher: Berlin : Springer,

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A guide to the diagnosis and treatment of human papillomavirus (HPV)-related diseases from a urological perspective. With a strong emphasis on the clinical aspects of genital HPV infection, it is suitable for urologists and medical practitioners wishing to acquire or expand their knowledge of urologic diseases caused by HPV.


Book
Color atlas of herpetic eye diseases : a practical guide to clinical management
Author:
ISBN: 3540694625 3642088996 9786611876227 1281876224 3540694633 Year: 2009 Publisher: Berlin : Springer-Verlag,

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