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Pediatric Inflammatory Bowel Disease, Second Edition provides an essential reference with an emphasis on the unique pediatric issues of IBD.  Chapters focus on complications of IBD specific to children and adolescents. Treatment recommendations are based on the latest clinical research available. The textbook also presents sections dedicated to the aspects of participation in clinical research unique to children and adolescents and the complicated yet vital process of successfully transitioning a patient from a pediatric to adult specialist. Controversies in pediatric IBD care such as the off-label use of medications are also covered.  The format incorporates multiple tables, graphs, and figures to improve readability and  make for an efficient reference for clinicians to use. Thoroughly revised and updated from the first edition, the volumes includes new therapies that are currently being used or tested for treatment of IBD, important areas regarding incidence and prevalence, immunization and response to vaccine administration as well as advancements in our understanding of growth and development with particular to the use of growth hormone therapy. Other new areas covered include important topics of complementary and alternative medicine use in IBD, immunization, and liver disease in IBD. Pediatric Inflammatory Bowel Disease, Second Edition is a valuable resource for pediatric gastroenterologists as well as adult gastroenterologists.

Inflammatory bowel diseases -- Immunological aspects. --- Inflammatory bowel diseases -- Treatment. --- Inflammatory bowel diseases. --- Medicine --- Health & Biological Sciences --- Gastroenterology --- Pediatrics. --- Children --- Diseases. --- Childhood diseases --- Children's diseases --- Diseases of children --- Juvenile diseases --- Paediatrics --- Pediatric medicine --- IBD (Disease) --- Inflammatory bowel disease --- Intestines --- Inflammation --- Medicine. --- Gastroenterology. --- Medicine & Public Health. --- Pediatrics --- Gastroenteritis --- Diseases --- Health and hygiene --- Internal medicine --- Digestive organs --- Gastroenterology .

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Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.

Chemistry. --- Medicinal Chemistry. --- Biochemistry. --- Chimie --- Biochimie --- Pharmaceutical chemistry. --- Virus diseases -- Diagnosis. --- Virus diseases -- Immunological aspects. --- Virus diseases -- Treatment. --- Health & Biological Sciences --- Pharmacy, Therapeutics, & Pharmacology --- Virus diseases --- Treatment. --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Viral diseases --- Viral infections --- Virus infections --- Chemistry --- Medicinal chemistry. --- Communicable diseases --- Medical virology --- Pathogenic viruses --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Medical sciences --- Composition

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Molecular Pathology of Liver Diseases integrates the traditional knowledge of physiological and pathological processes in the liver with a balanced emphasis on fundamental concepts; timely advances in cellular and molecular mechanisms; and applied pathology. The textbook is organized into several sections, each of which includes an array of chapters that progressively and cohesively elaborate on pertinent liver biology and pathology. The first three sections discuss the cellular composition of the liver along with their specialized functions, and further dissect the molecular basis of the cellular processes that are so unique to the liver. The next section examines the mechanisms that are commonly implicated in the cellular and molecular basis of several hepatic pathologies, followed eventually by a section each on a multitude of non-neoplastic and neoplastic diseases of the liver. Molecular Pathology of Liver Diseases is a comprehensive reference on liver pathobiology for basic, translational and clinical researchers and physicians The format of the volume will serve as a ready reference to relevant topics in the liver, thus providing a practical disease-based integrative resource on the molecular pathology of liver disease. Satdarshan (Paul) Singh Monga, MD is Director: Division of Experimental Pathology and Associate Professor of Pathology and Medicine, University of Pittsburgh, Pittsburgh, PA.

Liver -- Diseases -- Immunological aspects. --- Liver -- Diseases -- Molecular aspects. --- Liver -- Diseases. --- Digestive System --- Digestive System Diseases --- Diseases --- Anatomy --- Liver Diseases --- Liver --- Medicine --- Health & Biological Sciences --- Pathology --- Molecular aspects. --- Pathophysiology. --- Medicine. --- Molecular biology. --- Pathology. --- Medicine & Public Health. --- Molecular Medicine. --- Disease (Pathology) --- Medical sciences --- Medicine, Preventive --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Physicians --- Abdomen --- Biliary tract --- Health Workforce

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Immune System Diseases. --- Immune System --- Developmental immunology --- Clinical immunology --- Immunologie du développement --- Immunologie clinique --- immunology. --- growth & development. --- Periodicals. --- Périodiques --- Clinical immunology. --- Developmental immunology. --- immunity --- immunology --- autoantibodies --- immunoglobulins --- immunotherapy --- immunotoxins --- Immunology, Developmental --- Developmental biology --- Immunology --- Medical immunology --- Diseases of Immune System --- Immune Diseases --- Immunological Diseases --- Immune Disorders --- Immunologic Diseases --- Disease, Immune --- Disease, Immune System --- Disease, Immunologic --- Disease, Immunological --- Diseases, Immune --- Diseases, Immune System --- Diseases, Immunologic --- Diseases, Immunological --- Disorder, Immune --- Disorders, Immune --- Immune Disease --- Immune Disorder --- Immune System Disease --- Immunologic Disease --- Immunological Disease --- Allergy --- Immune System Disorders --- Disorder, Immune System --- Immune System Disorder --- allergieën --- Microbiology & Immunology

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Immunopathology --- Immunology --- Immune System Diseases. --- Allergy and Immunology. --- Pathology. --- Immune System Diseases --- Immunology. --- Immunopathology. --- diagnosis. --- Immunobiology --- Pathologies --- Disease --- Allergy Specialty --- Allergy, Immunology --- Immunology and Allergy --- Immunology, Allergy --- Specialty, Allergy --- Diseases of Immune System --- Immune Diseases --- Immunological Diseases --- Immune Disorders --- Immunologic Diseases --- Disease, Immune --- Disease, Immune System --- Disease, Immunologic --- Disease, Immunological --- Diseases, Immune --- Diseases, Immune System --- Diseases, Immunologic --- Diseases, Immunological --- Disorder, Immune --- Disorders, Immune --- Immune Disease --- Immune Disorder --- Immune System Disease --- Immunologic Disease --- Immunological Disease --- pathology --- Allergy and Immunology --- Pathology --- diagnosis --- Clinical immunology --- Life sciences --- Serology --- Immune System Disorders --- Disorder, Immune System --- Immune System Disorder --- Clinical Immunology --- Immunpathologie. --- Immunopathologie