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Presents an historical account of the Pharmacopoeia and describes methods and procedures for the quality control of pharmaceutical substances and dosage forms, including a special section on quality control of anti-malarials.

Pharmacopoeias. --- Pharmaceutical Preparations --- Chemicals and Drugs

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Technology, Industry, and Agriculture --- Technology --- Biological Science Disciplines --- Amino Acids, Peptides, and Proteins --- Industry --- Biotechnology --- Proteins --- Technology, Industry, Agriculture --- Natural Science Disciplines --- Chemicals and Drugs --- Disciplines and Occupations

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Galanin is a neuropeptide found both in the central and peripheral nervous system. The 29-amino acid peptide (named after its N-terminal glycine and C-terminal alanine) was identified in 1983 by its C-terminal amidation. This 'reverse' approach, that is to discover a substance through a distinct chemical feature, and only subsequently to characterize its biological activity, was novel and has been successful in the identification of several other peptides. After the structure of galanin was determined in 1983, functional studies were performed with material purified from natural sources until the synthetic form of the peptide became available. Galanin can act as transmitter, modulator and trophic factor, and is involved in a number of physiological processes such as hormone secretion, cardiovascular mechanisms, feeding and cognition. This peptide may also be of significance for a number of pathological processes/disorders including pain, depression, Alzheimer's disease, epilepsy, addiction and cancer. This wide diversity of actions is mediated by three galanin receptor subtypes. The studies reviewed in this volume give a fairly complete overview of the spectrum of the biological actions and functions of galanin and its receptors and on possible therapeutic applications in a number of pathological conditions.

Galanin -- Therapeutic use. --- Neuroendocrinology. --- Peptides. --- Galanin --- Neuropeptides --- Peptides --- Amino Acids, Peptides, and Proteins --- Chemicals and Drugs --- Animal Biochemistry --- Neuroscience --- Human Anatomy & Physiology --- Health & Biological Sciences --- Galanin. --- Neuropeptides. --- Brain peptides --- Life sciences. --- Neurobiology. --- Life Sciences. --- Nerve tissue proteins --- Neurotransmitters --- Neurosciences

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"Experiments in the Purification and Characterization of Enzymes: A Laboratory Manual provides students with a working knowledge of the fundamental and advanced techniques of experimental biochemistry. Included are instructions and experiments that involve purification and characterization of enzymes from various source materials, giving students excellent experience in kinetics analysis and data analysis. Additionally, this lab manual covers how to evaluate and effectively use scientific data. By focusing on the relationship between structure and function in enzymes, Experiments in the Purification and Characterization of Enzymes: A Laboratory Manual provides a strong research foundation for students enrolled in a biochemistry lab course by outlining how to evaluate and effectively use scientific data in addition to offering students a more hands-on approach with exercises that encourage them to think deeply about the content and to design their own experiments. Instructors will find this book useful because the modular nature of the lab exercises allows them to apply the exercises to any set of proteins and incorporate the exercises into their courses as they see fit, allowing for greater flexibility in the use of the material. Written in a logical, easy-to-understand manner, Experiments in the Purification and Characterization of Enzymes: A Laboratory Manual is an indispensable resource for both students and instructors in the fields of biochemistry, molecular biology, chemistry, pharmaceutical chemistry, and related molecular life sciences such as cell biology, neurosciences, and genetics. Offers project lab formats for students that closely simulate original research projects. Provides instructional guidance for students to design their own experiments . Includes advanced analytical techniques. Contains adaptable modular exercises that allow for the study proteins other than FNR, LuxG and LDH. Includes access to a website with additional resources for instructors"--Page 4 of cover.

Enzymes --- Publication Formats --- Enzymes and Coenzymes --- Chemicals and Drugs --- Publication Characteristics --- Laboratory Manuals --- Human Anatomy & Physiology --- Health & Biological Sciences --- Animal Biochemistry --- Analysis --- Biocatalysts --- Ferments --- Soluble ferments --- Catalysts --- Proteins --- Enzymology

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This book combines three fundamental areas of interest to the science and engineering community, these being material science, nanotechnology and molecular engineering. Although there have been various results published in this field, there has yet to be a fully comprehensive review. This book covers key research on molecular mechanisms and thermodynamic behaviour of (bio)polymer surfaces and interfaces, from theoretical and experimental perspectives.

Polymers. --- Biomedical and Dental Materials --- Macromolecular Substances --- Physicochemical Phenomena --- Manufactured Materials --- Chemicals and Drugs --- Chemical Phenomena --- Technology, Industry, and Agriculture --- Phenomena and Processes --- Technology, Industry, Agriculture --- Polymers --- Biopolymers --- Surface Properties