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PLATELETS is the definitive current source of state-of-the-art knowledge about platelets and covers the entire field of platelet biology, pathophysiology, and clinical medicine. Recently there has been a rapid expansion of knowledge in both basic biology and the clinical approach to platelet-related diseases including thrombosis and hemorrhage. Novel platelet function tests, drugs, blood bank storage methods, and gene therapies have been incorporated into patient care or are in development. This book draws all this information into a single, comprehensive and authoritative resource.

Blood platelets. --- Blood platelet disorders. --- Thrombocytopathy --- Platelets --- Thrombocytes --- Blood --- Blood cells --- Megakaryocytes --- Diseases

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The editor has incorporated scientific contributions from a diverse group of leading researchers in the field of hematology and related blood cell research. This book aims to provide an overview of current knowledge pertaining to our understanding of hematology. The main subject areas will include blood cell morphology and function, the pathophysiology and genetics of hematological disorders and malignancies, blood testing and typing, and the processes governing hematopoiesis. Blood cell physiology, biochemistry and blood flow are covered in this book. This text is designed for hematologists, pathologists and laboratory staff in training and in practice. The work presented in this book will be of benefit to medical students and to researchers of hematology and blood flow in the microcirculation.This book is written primarily for those who have some knowledge of chemistry, biochemistry and general hematology. The authors of each section bring a strong clinical emphasis to the book.

Blood cells. --- Blood --- Blood corpuscles --- Corpuscles, Blood --- Haemocytes --- Hemic cells --- Hemocytes --- Cells --- Corpuscles and platelets --- Haematology

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Insights into the regulation of immune cell lineage differentiation and specification as well as into the control of lineage integrity, stability and plasticity are of fundamental importance to understanding innate and adaptive immune responses. In this volume, leading experts provide an up-to-date and comprehensive overview of recent advances in the transcriptional control mechanisms and transcription factor networks that regulate these processes in a variety of different immune cell lineages. The chapters cover the regulation of T versus B cell lineage choice, discuss early B cell development and pre-B cell leukemia prevention, address transcriptional control mechanisms during Th differentiation, in regulatory T cells and iNKT cells, detail genomic switches in helper cell fate choice and plasticity, and highlight the role of the BTB-zinc finger family of transcription factors in T cells. Moreover, the chapters discuss transcriptional networks in DCs, NK cells and in innate lymphoid cells. Together, the reviews illustrate key transcriptional control mechanisms that regulate the development and function of immune cells and demonstrate the impressive advances made over the last decade.

Blood cells. --- Blood --- Blood corpuscles --- Corpuscles, Blood --- Haemocytes --- Hemic cells --- Hemocytes --- Cells --- Corpuscles and platelets --- Immunology. --- Immunobiology --- Life sciences --- Serology

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Make sure you are thoroughly prepared to work in a clinical lab. Rodak's Hematology: Clinical Principles and Applications, 6^th Edition uses hundreds of full-color photomicrographs to help you understand the essentials of hematology. This new edition shows how to accurately identify cells, simplifies hemostasis and thrombosis concepts, and covers normal hematopoiesis through diseases of erythroid, myeloid, lymphoid, and megakaryocytic origins. Easy to follow and understand, this book also covers key topics including: working in a hematology lab; complementary testing areas such as flow cytometry, cytogenetics, and molecular diagnostics; the parts and functions of the cell; and laboratory testing of blood cells and body fluid cells. UPDATED nearly 700 full-color illustrations and photomicrographs make it easier for you to visualize hematology concepts and show what you'll encounter in the lab, with images appearing near their mentions in the text to minimize flipping pages back and forth. UPDATED content throughout text reflects latest information on hematology. Instructions for lab procedures include sources of possible errors along with comments. Hematology instruments are described, compared, and contrasted. Case studies in each chapter provide opportunities to apply hematology concepts to real-life scenarios. Hematology/hemostasis reference ranges are listed on the inside front and back covers for quick reference. A bulleted summary makes it easy for you to review the important points in every chapter. Learning objectives begin each chapter and indicate what you should achieve, with review questions appearing at the end. A glossary of key terms makes it easy to find and learn definitions. NEW! Additional content on cell structure and receptors helps you learn to identify these organisms. NEW! New chapter on Introduction to Hematology Malignancies provides and overview of diagnostic technology and techniques used in the lab.

Hematology. --- Blood --- Hematologic Diseases --- Blood Cells --- Hematologic Tests --- Hematopoiesis. --- Hemostasis. --- Diseases. --- diagnosis. --- physiology. --- methods. --- Hematology --- Hematopoiesis --- Hemostasis --- physiology --- methods --- diagnosis

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Platelets in Cardiovascular Disease provides an in-depth and current coverage of relevant platelet biology and antiplatelet therapy that is in clinical use today and potentially for the future. The book provides a succinct overview of the critical role of platelets in cardiovascular medicine. Cardiovascular disease is the leading cause of mortality worldwide, and recent research has found that the platelet is central to the genesis of heart attacks and stroke as well as many of the complications of angioplasty and bypass surgery. An explosion of knowledge of the biology of platelets has established their important role in the formation of blood clots and, perhaps more intriguingly, their role as inflammatory cells. This growth in information has been paralleled by the development of several drugs that can interfere with platelet action and thereby improve patient outcomes. Indeed, several antiplatelet drugs already in development may ultimately lead to marked advances in both the treatment and prevention of cardiovascular disease. Drawing upon a panel of international experts, Platelets in Cardiovascular Disease delivers a concise yet thorough review of the major developments in antiplatelet therapy. Practicing clinicians as well as those involved in the development of new antithrombotic therapies will find the book interesting and useful.

Cardiovascular agents. --- Blood platelets. --- Cardiovascular system --- Cardiovascular diseases --- Platelets --- Thrombocytes --- Blood cells --- Megakaryocytes --- Cardiac drugs --- Cardiovascular drugs --- Drugs --- Heart --- Diseases. --- Diseases --- Chemotherapy