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Book
Handbook of non-motor symptoms in Parkinson's disease
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ISBN: 1907673237 1908517603 1283945398 Year: 2011 Publisher: New York : Springer,

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Abstract

Handbook of Non-Motor Symptoms in Parkinson’s Disease is designed to provide practical tips and emphasize key priorities for treatment of non-motor aspects of the disorder. The quick-reference handbook format, with key points highlighted by the use of figures and tables, will provide the reader with high-value practical information.


Book
Personalized Medicine for Parkinson's Disease : New Concepts and Future of Individualized Management
Authors: ---
ISBN: 3036562117 3036562125 Year: 2023 Publisher: [Place of publication not identified] : MDPI - Multidisciplinary Digital Publishing Institute,

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Personalized medicine for Parkinson's disease is a growing and emerging concept in light of recent recognition that Parkinson's is a syndromic condition affecting multiple neurotransmitter systems, as well as brain and extracranial structures. The clinical expression is, thus, heterogeneous, and presentation age can range from the 30s to the 90s, with PD in older patients being associated with significant neuropathological comorbidity as well, involving not just misfolded alpha synuclein deposition but also amyloid and tau. Traditional and largely guideline-driven "one size fits all" management strategies adopted in clinical practice are, therefore, often inadequate in holistic management of a patient, particularly when aspects of motor and nonmotor symptoms are taken into consideration. In this supplement of JPM, we present a selection of papers which address several possible strands of personalized medicine in PD, ranging from genomic precision medicine to digital "checklists" to ensure delivery of holistic personalized medicine involving nonpharmacological strategies, as well. We are soliciting any papers addressing biomarkers, genetics and pharmacogenetics, treatment or complementary therapies for personalized or individualized treatment for PD.


Book
Restless legs syndrome
Authors: --- ---
ISBN: 0191739987 0199607109 1283582112 9786613894564 0191552968 9780191552960 9780199234882 0199234884 Year: 2009 Publisher: Oxford ; New York : Oxford University Press,

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Restless legs syndrome (RLS), also known as Ekbom syndrome, is a common movement disorder with sensorimotor symptoms occurring during sleep and quiet wakefulness. Yoakum described RLS as the ""the most common disorder you've never heard of"" and this may, unfortunately, be an appropriate description of RLS. The term ""restless legs syndrome was first introduced by Karl-Axel Ekbom, a Swedish neurologist and surgeon in 1945. RLS can present in the primary care and secondary care, acrossa range of specialities such as psychiatry, rheumatology and sleep medicine, and in the UK, the condition remai


Book
Non-motor symptoms of parkinson's disease
Authors: --- --- ---
ISBN: 0191753238 1283579545 9786613891990 0191553263 9780191553264 9780199237234 0199237239 9780191753237 9781283579544 6613891991 Year: 2009 Publisher: Oxford Oxford University Press

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Patients with Parkinson's disease (PD) are known to suffer from motor symptoms of the disease, but they also experience non-motor symptoms (NMS) that are often present before diagnosis or that inevitably emerge with disease progression. The motor symptoms of Parkinson's disease have been extensively researched, and effective clinical tools for their assessment and treatment have been developed and are readily available. In contrast, researchers have only recently begun to focus onthe NMS of Parkinson's Disease, which are poorly recognized and inadequately treated by clinicians.The NMS of PD ha


Book
Movement disorders in clinical practice
Authors: --- --- --- ---
ISBN: 184996064X 9786612983184 1849960658 1282983180 Year: 2010 Publisher: New York : Springer,

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Abstract

Movement disorders attack the part of the brain that controls our movements, they are a complex group of disorders, spanning all aspects of neurological illnesses. Such disorders are widespread, often destroying the independence of those affected. Movement Disorders in Clinical Practice provides a concise, practical overview of the diagnosis, treatment and management of patients with these debilitating conditions, including a brief evaluation of ongoing clinical trials. Edited by two key international movement disorder experts, chapters cover: Parkinson’s disease Parkinsonian syndromes Dystonia Tremor Restless legs syndrome An overview of other movement disorders.


Book
Handbook of movement disorders
Authors: --- --- --- ---
ISBN: 1858734401 9786613355300 1283355302 1908517042 Year: 2009 Publisher: London : Current Medicine Group,

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Abstract

Movement disorders are a complex group of disorders spanning all aspects of neurological illnesses and range from conditions characterized by too little movement (hypokinesis) to those where movement is excessive (hyperkinesis). The classic example would be Parkinson’s disease, while other movement-related problems, such as tremor, chorea, dystonia, myoclonus, hemiballism and tics, occur in a range of inherited, drug-induced and sporadic disorders. Genetics plays an important part in the genesis of several conditions characterized by various movement disorders, such as Huntington’s disease, dystonic conditions and myoclonus. Somatization from psychologically determined conditions can also manifest as movement disorders. Finally, sleep may be affected by movement disorders and a typical example would be restless legs syndrome. To non-experts, movement disorders may appear to be complex, sometimes bizarre and difficult to manage. Diagnosis is based mostly on observation and examination rather than radiology and serological assessments. This comp- hensive handbook deals with all the above movement disorders in a holistic manner, providing a detailed “snapshot” view of these complex disorders. As well as being useful to the general physician working in clinical settings where movement disorders often first present, such as accident and emergency depa- ments or in primary care, we hope that the up-to-date information will be useful for trainees and experts in the field of movement disorders. Chapter 1 Parkinson’s disease Kartik Logishetty and K Ray Chaudhuri Introduction Parkinson’s disease was first described by the London physician, James Parkinson, in 1817 and later named after him by Charcot.


Book
Non-motor symptoms of Parkinson's disease
Authors: --- --- --- ---
ISBN: 0191797669 0191047430 9780191047435 9780199684243 0191047449 Year: 2014 Publisher: New York, New York

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Researchers have only recently begun to focus on the non-motor symptoms of Parkinson's Disease, which are poorly recognized and inadequately treated by clinicians. This resource discusses the significant impact on patient quality of life and mortality caused by NMS of Parkinson's, which include neuropsychiatric, sleep-related, autonomic, gastrointestinal, and sensory symptoms. While some NMS can be improved with currently available treatments, others may be more refractory and will require research into novel (non-dopaminergic) drug therapies for the future.

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