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Handbook of Non-Motor Symptoms in Parkinson’s Disease is designed to provide practical tips and emphasize key priorities for treatment of non-motor aspects of the disorder. The quick-reference handbook format, with key points highlighted by the use of figures and tables, will provide the reader with high-value practical information.
Disease Models, Animal -- Collected Works. --- Parkinson Disease -- genetics -- Collected Works. --- Parkinson Disease -- physiopathology -- Collected Works. --- Parkinson's disease --- Parkinsonian Disorders --- Basal Ganglia Diseases --- Brain Diseases --- Central Nervous System Diseases --- Nervous System Diseases --- Diseases --- Parkinson Disease --- Medicine --- Health & Biological Sciences --- Geriatrics --- Diagnosis --- Pathophysiology --- Palsy, Shaking --- Paralysis agitans --- Parkinson disease --- Parkinsonism --- Shaking palsy --- Medicine. --- Gastroenterology. --- Geriatrics. --- Neurology. --- Psychotherapy. --- Urology. --- Medical research. --- Quality of life. --- Medicine & Public Health. --- Geriatrics/Gerontology. --- Quality of Life Research. --- Brain --- Extrapyramidal disorders --- Quality of Life --- Research. --- Psychagogy --- Therapy (Psychotherapy) --- Mental illness --- Clinical sociology --- Mental health counseling --- Nervous system --- Neuropsychiatry --- Genitourinary organs --- Internal medicine --- Digestive organs --- Life, Quality of --- Economic history --- Human ecology --- Life --- Social history --- Basic needs --- Human comfort --- Social accounting --- Work-life balance --- Gerontology --- Older people --- Treatment --- Health and hygiene --- Gastroenterology . --- Neurology . --- Psychotherapy . --- Biomedical research --- Medical research
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Personalized medicine for Parkinson's disease is a growing and emerging concept in light of recent recognition that Parkinson's is a syndromic condition affecting multiple neurotransmitter systems, as well as brain and extracranial structures. The clinical expression is, thus, heterogeneous, and presentation age can range from the 30s to the 90s, with PD in older patients being associated with significant neuropathological comorbidity as well, involving not just misfolded alpha synuclein deposition but also amyloid and tau. Traditional and largely guideline-driven "one size fits all" management strategies adopted in clinical practice are, therefore, often inadequate in holistic management of a patient, particularly when aspects of motor and nonmotor symptoms are taken into consideration. In this supplement of JPM, we present a selection of papers which address several possible strands of personalized medicine in PD, ranging from genomic precision medicine to digital "checklists" to ensure delivery of holistic personalized medicine involving nonpharmacological strategies, as well. We are soliciting any papers addressing biomarkers, genetics and pharmacogenetics, treatment or complementary therapies for personalized or individualized treatment for PD.
Parkinson's disease --- Treatment. --- Diagnosis. --- Palsy, Shaking --- Paralysis agitans --- Parkinson disease --- Parkinsonism --- Shaking palsy --- Brain --- Extrapyramidal disorders --- Diseases
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Restless legs syndrome (RLS), also known as Ekbom syndrome, is a common movement disorder with sensorimotor symptoms occurring during sleep and quiet wakefulness. Yoakum described RLS as the ""the most common disorder you've never heard of"" and this may, unfortunately, be an appropriate description of RLS. The term ""restless legs syndrome was first introduced by Karl-Axel Ekbom, a Swedish neurologist and surgeon in 1945. RLS can present in the primary care and secondary care, acrossa range of specialities such as psychiatry, rheumatology and sleep medicine, and in the UK, the condition remai
Restless legs syndrome. --- Sleep disorders. --- Disorders of sleep --- Nervous system --- Psychology, Pathological --- Asthenia crurum paresthetica --- Ekbom syndrome --- Ekbom's syndrome --- Restless leg syndrome --- Wittmaack-Ekbom syndrome --- Insomnia --- Movement disorders --- Diseases
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Patients with Parkinson's disease (PD) are known to suffer from motor symptoms of the disease, but they also experience non-motor symptoms (NMS) that are often present before diagnosis or that inevitably emerge with disease progression. The motor symptoms of Parkinson's disease have been extensively researched, and effective clinical tools for their assessment and treatment have been developed and are readily available. In contrast, researchers have only recently begun to focus onthe NMS of Parkinson's Disease, which are poorly recognized and inadequately treated by clinicians.The NMS of PD ha
Parkinson's disease --- Palsy, Shaking --- Paralysis agitans --- Parkinson disease --- Parkinsonism --- Shaking palsy --- Brain --- Extrapyramidal disorders --- Diagnosis. --- Pathophysiology. --- Diseases --- Ziekte van Parkinson --- Symptoom
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Movement disorders attack the part of the brain that controls our movements, they are a complex group of disorders, spanning all aspects of neurological illnesses. Such disorders are widespread, often destroying the independence of those affected. Movement Disorders in Clinical Practice provides a concise, practical overview of the diagnosis, treatment and management of patients with these debilitating conditions, including a brief evaluation of ongoing clinical trials. Edited by two key international movement disorder experts, chapters cover: Parkinson’s disease Parkinsonian syndromes Dystonia Tremor Restless legs syndrome An overview of other movement disorders.
Movement disorders. --- Movement disorders --- Medicine --- Health & Biological Sciences --- Neurology --- Dyskinesia --- Dyskinesias --- Motor disorders --- Medicine. --- Emergency medicine. --- General practice (Medicine). --- Neurology. --- Medicine & Public Health. --- General Practice / Family Medicine. --- Emergency Medicine. --- Disabilities --- Nervous system --- Diseases --- Family medicine. --- Medicine, Emergency --- Critical care medicine --- Disaster medicine --- Medical emergencies --- Family practice (Medicine) --- General practice (Medicine) --- Physicians (General practice) --- Neuropsychiatry --- Neurology .
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Movement disorders are a complex group of disorders spanning all aspects of neurological illnesses and range from conditions characterized by too little movement (hypokinesis) to those where movement is excessive (hyperkinesis). The classic example would be Parkinson’s disease, while other movement-related problems, such as tremor, chorea, dystonia, myoclonus, hemiballism and tics, occur in a range of inherited, drug-induced and sporadic disorders. Genetics plays an important part in the genesis of several conditions characterized by various movement disorders, such as Huntington’s disease, dystonic conditions and myoclonus. Somatization from psychologically determined conditions can also manifest as movement disorders. Finally, sleep may be affected by movement disorders and a typical example would be restless legs syndrome. To non-experts, movement disorders may appear to be complex, sometimes bizarre and difficult to manage. Diagnosis is based mostly on observation and examination rather than radiology and serological assessments. This comp- hensive handbook deals with all the above movement disorders in a holistic manner, providing a detailed “snapshot” view of these complex disorders. As well as being useful to the general physician working in clinical settings where movement disorders often first present, such as accident and emergency depa- ments or in primary care, we hope that the up-to-date information will be useful for trainees and experts in the field of movement disorders. Chapter 1 Parkinson’s disease Kartik Logishetty and K Ray Chaudhuri Introduction Parkinson’s disease was first described by the London physician, James Parkinson, in 1817 and later named after him by Charcot.
Movement disorders -- Handbooks, manuals, etc. --- Movement disorders -- Handbooks. --- Movement disorders. --- Medicine --- Health & Biological Sciences --- Neurology --- Movement disorders --- Dyskinesia --- Dyskinesias --- Motor disorders --- Medicine. --- Neurology. --- Medicine & Public Health. --- Disabilities --- Nervous system --- Diseases --- Neuropsychiatry --- Neurology .
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Researchers have only recently begun to focus on the non-motor symptoms of Parkinson's Disease, which are poorly recognized and inadequately treated by clinicians. This resource discusses the significant impact on patient quality of life and mortality caused by NMS of Parkinson's, which include neuropsychiatric, sleep-related, autonomic, gastrointestinal, and sensory symptoms. While some NMS can be improved with currently available treatments, others may be more refractory and will require research into novel (non-dopaminergic) drug therapies for the future.
Parkinson's disease --- Palsy, Shaking --- Paralysis agitans --- Parkinson disease --- Parkinsonism --- Shaking palsy --- Brain --- Extrapyramidal disorders --- Diagnosis. --- Pathophysiology. --- Diseases
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