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The book “Protective and Detrimental Role of Heme Oxygenase-1”, includes a selection of original research papers and reviews aimed at understanding the dual role (protective and detrimental) of HO-1 and the involved signaling pathways. Original research papers and reviews aimed at the identification of natural molecules or new synthetic compounds able to modulate HO-1 activity/expression help make HO-1 a potential therapeutic target for the amelioration of various diseases.
coronary artery disease --- n/a --- glucocorticoid receptor --- antigen presentation --- analgesia --- chemotherapy --- locus coeruleus --- Sirtuin 1 --- thiol groups --- Heme Oxygenase-1 --- Betula etnensis Raf. --- heme oxygenase 1 --- tolerance --- heme oxygenase --- atherosclerosis --- nitric oxide --- caloric restriction --- liver --- carbon monoxide --- ER stress --- heme oxygenase-1 --- mineralocorticoid receptor --- Type 1 diabetes mellitus (T1D) --- Gamma-Glutamyl-Cysteine Ligase (GGCL) --- angiotensin II --- bilirubin --- Heme oxygenase-1 (HO-1) inducers --- Inducible nitric oxide synthase (iNOS) --- HO-1 activity inhibitor --- ferroptosis --- Myristica fragrans kernels --- glutathione --- high-pressure gas --- apoptosis --- HO-1 --- diabetes mellitus --- Caffeic acid phenethyl ester (CAPE) --- carotid plaque --- ischemia–reperfusion injury --- ANTIGEN presenting cell --- LPS --- endoplasmic reticulum stress --- hemoglobin --- Pancreatic oxidative damage --- Colon cancer --- inflammation --- reactive oxygen species --- inflammatory pain --- paracetamol --- cardiomyopathy --- heme oxigenase-1 --- adipocytes --- sirtuin 1 --- peripheral artery disease --- PGC-1? --- heme --- Reactive oxygen species (ROS) --- metformin --- GR --- prostate cancer --- NF-?B --- hyperbilirubinemia --- iron --- Tet-ON system --- lung preservation --- oxidative stress --- Gunn rats --- Dimethylarginine dimethylaminohydrolase-1 (DDAH-1) --- ischemia-reperfusion injury
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Based on their potent antioxidant properties, the possible exploitation of natural phenolic compounds as food supplements as well as functional ingredients in the food and cosmetic industry is gaining more and more attention. This book contains original research articles and a review reporting innovative applications of natural phenolic compounds in the field of nutrition and biomedicine, as active ingredients for the prevention of oxidative-stress-related diseases, and as additives in smart food packaging, biomedical devices, and cosmetic products. The growing importance of agri-food wastes as easily accessible sources of phenolic compounds as well as of synthetic derivatives of natural compounds with improved antioxidant properties is also highlighted. Finally, novel technologies to improve extraction yields, stability, bioavailability, and delivery of antioxidant compounds for healthcare products or for skin applications are described.
agri-food waste --- exhausted wood --- antioxidant --- DPPH assay --- FRAP assay --- tannins --- heavy metals --- methylene blue --- nitric oxides --- acid hydrolysis --- tyrosol --- homovanillyl alcohol --- hydroxytyrosol --- dimethyl carbonate --- lipophilic alkyl esters --- hydroxytyrosol-enriched extracts --- Olea europaea --- green chemistry --- circular economy --- feijoa extracts --- mercury --- red blood cells --- oxidative stress --- glutathione --- thiol groups --- functional food --- resveratrol --- nanostructured lipid carriers (NLC) --- factorial design --- high shear homogenization --- ultrasound method --- analysis of variance (ANOVA) --- spray drying --- blueberry juice-maltodextrins --- conservation of antioxidants --- encapsulation --- electrospinning --- polyphenol --- açaí (Euterpe oleracea Mart.) --- zein --- antioxidants --- orange essential oil --- xoconostle --- maturation --- antioxidant activity --- ginsenosides --- Panax quinquefolius --- puffing --- mentha --- heat stress --- antioxidant enzyme activity --- salicylic acid --- melatonin --- essential oil --- solubility --- nanoparticle --- correlation --- supercritical fluid --- bioavailability --- cannabidiol --- cannabidiol synthetic derivatives --- endocannabinoids --- lipid peroxidation --- inflammation --- membrane receptors --- propolis --- cytotoxic --- antibacterial --- México --- HS-SPME/GC-MS-TOF --- NMR --- volatile compounds --- flavonoids --- phenolic acids --- isoliquiritigenin (ISL) --- triple-negative breast cancer --- apoptosis --- autophagy --- 5,6-dihydroxyindole-2-carboxylic acid --- gelatin --- cross-linked hydrogel --- controlled release --- melanins --- photoprotection --- UVA --- HaCaT cells --- reactive oxygen species --- Nrf-2 --- n/a --- açaí (Euterpe oleracea Mart.) --- México
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