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A. H. Louie's More Than Life Itself is an exploratory journey in relational biology, a study of life in terms of the organization of entailment relations in living systems. This book represents a synergy of the mathematical theories of categories, lattices, and modelling, and the result is a synthetic biology that provides a characterization of life. Biology extends physics. Life is not a specialization of mechanism, but an expansive generalization of it. Organisms and machines share some common features, but organisms are not machines. Life is defined by a relational closure that places it beyond the reach of physicochemical and mechanistic dogma, outside the reductionistic universe, and into the realm of impredicativity. Function dictates structure. Complexity brings forth living beings.
Biology --- Biological systems. --- Biosystems --- Systems, Biological --- System theory --- Systems biology --- Vitalism --- Philosophy. --- Philosophy
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This book analyses the impact computerization has had on contemporary science and explains the origins, technical nature and epistemological consequences of the current decisive interplay between technology and science: an intertwining of formalism, computation, data acquisition, data and visualization and how these factors have led to the spread of simulation models since the 1950s. Using historical, comparative and interpretative case studies from a range of disciplines, with a particular emphasis on the case of plant studies, the author shows how and why computers, data treatment devices and programming languages have occasioned a gradual but irresistible and massive shift from mathematical models to computer simulations.
Biological systems --- Mathematical models. --- Computer simulation. --- Biosystems --- Systems, Biological --- Biology --- System theory --- Systems biology --- Philosophy
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A comprehensive guide to the revolutionary area of systems biology and its application in cell culture engineering, this volume presents an overall picture of the current topics central to structural and functional genomics, proteomics, metabolomics and bioinformatics, including such hot topics as RNAi, metabolic engineering and unfolded protein response. It includes reviews of the cellular response of environmental modulation such as low temperature and osmolarity, critical assessments of the applications of metabolomics and fluxomics approaches, examination of the utility of modulation of key genes and a presentation of a theory of chemical organisation which provides a new view of the system's structure. The clearly written chapters by experts in the field describe methods applicable to investigating the unique facets of cell culture. The book should be of interest to all those working in cell culture development and drug discovery in pharmaceutical and biotechnology companies as well as in academic institutions. It provides an invaluable resource for students and researchers in biotechnology, cell culture, genomics and bioinformatics.
Cell physiology. --- Biological systems. --- Biosystems --- Systems, Biological --- Biology --- System theory --- Systems biology --- Cell function --- Cytology --- Physiology --- Philosophy
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biology --- medicine --- anatomy --- biochemistry --- bioinformatics --- cell biology --- Biological systems --- Biological systems. --- Biosystems --- Systems, Biological --- Biology --- System theory --- Systems biology --- Philosophy
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This fine collection of essays by a leading philosopher of science presents a defence of integrative pluralism as the best description for the complexity of scientific inquiry today. The tendency of some scientists to unify science by reducing all theories to a few fundamental laws of the most basic particles that populate our universe is ill-suited to the biological sciences, which study multi-component, multi-level, evolved complex systems. This integrative pluralism is the most efficient way to understand the different and complex processes - historical and interactive - that generate biological phenomena. This book will be of interest to students and professionals in the philosophy of science.
Biological systems. --- Biology --- Philosophy of science --- Biological systems --- Biosystems --- Systems, Biological --- System theory --- Systems biology --- Philosophy --- Arts and Humanities
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Mechatronics --- Biological systems --- Biosystems --- Systems, Biological --- Biology --- System theory --- Systems biology --- Mechanical engineering --- Microelectronics --- Microelectromechanical systems --- Philosophy
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Organisms endowed with life show a sense of awareness, interacting with and learning from the universe in and around them. Each level of interaction involves transfer of information of various kinds, and at different levels. Each thread of information is interlinked with the other, and woven together, these constitute the universe - both the internal self and the external world - as we perceive it. They are, figuratively speaking, Nature''s longest threads. This volume reports inter-disciplinary research and views on information and its transfer at different levels of organization by reputed s
Quantum theory --- Biological systems --- Information theory in biology. --- Biology --- Biomathematics --- Biosystems --- Systems, Biological --- System theory --- Systems biology --- Mathematics. --- Measurement. --- Philosophy
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Systems Biology is concerned with the quantitative study of complex biosystems at the molecular, cellular, tissue, and systems scales. Its focus is on the function of the system as a whole, rather than on individual parts. This exciting new arena applies mathematical modeling and engineering methods to the study of biological systems. This book is the first of its kind to focus on the newly emerging field of systems biology with an emphasis on computational approaches. The work covers new concepts, methods for information storage, mining and knowledge extraction, reverse engineering of
Computational Biology. --- Systems Biology. --- Biological systems --- Systèmes biologiques --- Computer simulation. --- Simulation par ordinateur --- Systems biology. --- Biosystems --- Systems, Biological --- Biology --- System theory --- Systems biology --- Philosophy
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"The field of artificial life has recently emerged through the interaction of research in biology, physics, parallel computing, artificial intelligence, and complex adaptive systems. The goal is to understand, through synthetic experiments, the organizational principles underlying the dynamics (usually the nonlinear dynamics) of living systems. This book brings together contributions to the Fourth Artificial Life Workshop, held at the Massachusetts Institute of Technology in the summer of 1994"--Publisher's description.
Biological systems --- Computer simulation --- Congresses. --- Simulation methods --- Biology --- Health & Biological Sciences --- Biology - General --- Congresses --- Biosystems --- Systems, Biological --- System theory --- Systems biology --- Philosophy --- Use of --- Computers
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Systems biology --- Bioinformatics --- Biological systems --- Molecular biology --- Genomics --- Biosystems --- Systems, Biological --- Bio-informatics --- Biological informatics --- Systems Biology. --- Systems biology. --- Biology, Systems --- Biology --- Computational biology --- Systems Theory
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