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Polyphenols in Human Health and Disease documents antioxidant actions of polyphenols in protection of cells and cell organelles, critical for understanding their health-promoting actions to help the dietary supplement industry. The book begins by describing the fundamentals of absorption, metabolism and bioavailability of polyphenols, as well as the effect of microbes on polyphenol structure and function and toxicity. It then examines the role of polyphenols in the treatment of chronic disease, including vascular and cardiac health, obesity and diabetes therapy, cancer treatment and

Polyphenols --- Physiological effect. --- Polyhydroxy phenols --- Polyhydroxylated phenols --- Phenols --- Polyphenols.

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"Phenolic compounds are structures found in plant-based foods that play an important role in regulating health and disease. Accordingly, this book presents seven chapters that explore phenolic compounds from a variety of perspectives. Chapter One addresses the current knowledge about the presence of phenolic compounds in plants, their bioavailability and protective effects of interest for diabetes mellitus. Chapter Two describes the Bignoniaceae family and Handroanthus impetiginosus, as well as the main groups of phenolic compounds reported for this species and their main biological activities. Chapter Three highlights some scientific evidence corroborating the role of polyphenols in the prevention and treatment of cancer. Chapter Four presents the results of a study that indicate that L. leucocephala calli are promising biotechnological products for obtaining phenolic compounds in vitro. Chapter Five details a study that assessed the phenolic compound content and antioxidant and antibacterial activities of extracts and fractions of Bauhinia holophylla. Chapter Six evaluates the production of phenolic compounds in cell suspensions of B. variegate. Finally, Chapter Seven provides an insight on the anti-inflammatory activities of galangin through attenuation of allergic inflammation, regulation of PPARy pathway, inhibition of ERK, NF-kappaB, PI3K/AKT and NLRP3 signaling, interplaying of MAPK signaling cascade, and through activation of Nrf2 signaling in animal models"--

Phenols --- Physiological effect.

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Polyphenols. --- Plant polyphenols. --- Plant polymers --- Polyphenols --- Polyhydroxy phenols --- Polyhydroxylated phenols --- Phenols

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Phenolic acids. --- Polyphenols. --- Phytochemicals. --- Polyhydroxy phenols --- Polyhydroxylated phenols --- Phenols --- Organic acids --- Botanical chemicals --- Plant chemicals --- Chemicals --- Botanical chemistry

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Phenols. --- Phenols --- Wine --- Phenolic compounds --- Phenolics --- Alcohols --- Antiseptics --- Aromatic compounds --- Physiological effect. --- Composition.