Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Psychopharmacology is the study of the effects of psychoactive drugs on the functioning of the central nervous system at all levels of analysis, thus embracing cognition, behaviour, psychological states, neurophysiology, neurochemistry, gene expression and molecular biology. It includes, as an integral part of its domain, the interaction of environmental and genetic factors with psychoactive drug action, their medicinal and social uses, and their abuse. The Encyclopedia of Psychopharmacology provides detailed information on psychopharmacology and its sub-disciplines, such as clinical psychopharmacology, molecular neuropsychopharmacology, behavioural pharmacology in laboratory animals, preclinical psychopharmacology, human experimental psychopharmacology. The wide-ranging entries in the Encyclopedia of Psychopharmacology are written by leading experts. They will provide basic and clinical scientists in academia as well as industry with valuable information about the field of psychopharmacology. Also people in related fields, students, teachers, and interested laypeople will benefit from the important and relevant information on the most recent developments of psychopharmacology. Entries will fall into several main categories: Methods, techniques and target systems (explaining nature of a technique and its uses and limitations) - Drugs and classes of drug (mainly describing effects and mechanisms of action) - Psychiatric states (explaining drugs used to treat them) - Miscellaneous currently interesting topics that do not fall within the above (e.g. cognitive enhancement, regulation and licensing, substance use in religious rituals).

Pharmacology. --- Molecular biology. --- Medicine. --- Pharmacology/Toxicology. --- Molecular Medicine. --- Biomedicine, general.

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This book introduces readers to essential methods and applications in translational biomedical informatics, which include biomedical big data, cloud computing and algorithms for understanding omics data, imaging data, electronic health records and public health data. The storage, retrieval, mining and knowledge discovery of biomedical big data will be among the key challenges for future translational research. The paradigm for precision medicine and healthcare needs to integratively analyze not only the data at the same level – e.g. different omics data at the molecular level – but also data from different levels – the molecular, cellular, tissue, clinical and public health level. This book discusses the following major aspects: the structure of cross-level data; clinical patient information and its shareability; and standardization and privacy. It offers a valuable guide for all biologists, biomedical informaticians and clinicians with an interest in Precision Medicine Informatics.

Bioinformatics. --- Molecular biology. --- Molecular Medicine. --- Computational Biology/Bioinformatics.

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Molecular diagnosis. --- Diagnosis --- Molecular diagnostics --- Molecular biology --- Molecular aspects --- Molecular Medicine --- methods --- instrumentation

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This book covers the mechanisms of renal cyst development as well as the aberrant signaling pathways which are involved in Autosomal Dominant Polycystic Kidney Disease (ADPKD). ADPKD is a genetic disease in which cysts appear in the epithelial lining of both kidneys. End stage ADPKD patients experience renal failure and require dialysis or a renal transplantation. There are no specific targeted therapies for ADPKD currently available, making it important to understand the basic cellular mechanisms underlying the onset and progression of ADPKD, in order to identify potential therapeutic targets for the disease. Several therapeutic approaches that have been attempted to date are reviewed. This work provides a broad overview of ADPKD and highlights the key challenges currently faced by researchers in this field. Furthermore, it provides insight into ADPKD to facilitate the development of novel biomarkers for ADPKD and to direct future research into this challenging pathology. This book is suitable for clinicians who have encountered patients with ADPKD, for clinicians / researchers working in the field of ADPKD and more generally on the kidney and kidney related disorders and for students of medicine with an interest in internal medicine.

Human genetics. --- Molecular biology. --- Cell biology. --- Medical microbiology. --- Human Genetics. --- Molecular Medicine. --- Cell Biology. --- Medical Microbiology.

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This book offers a comprehensive but highly readable compilation of papers on the role of dopamine in sleep and sleep disorders. Leading experts in sleep medicine, psychiatry and neuroendocrinology provide a broad perspective on the field, from established theories to the latest research advances. Accordingly, it represents an interdisciplinary, cutting-edge guide for sleep disorder specialists, sleep researchers, psychiatrists, neurologists, pulmonologists, psychologists, and behavioral sleep medicine specialists.

Pharmacology. --- Molecular biology. --- Neurochemistry. --- Neurology . --- Psychopharmacology. --- Pharmacology/Toxicology. --- Molecular Medicine. --- Neurology.