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Biofilms are ubiquitous and their presence in industry can lead to production losses. However, nowhere do biofilms impact human health and welfare as much as those that are found contaminating the healthcare environment, surgical instruments, equipment, and medical implantable devices. Approximately 70% of healthcare-associated infections are due to biofilm formation, resulting in increased patient morbidity and mortality. Biofilms formed on medical implants are recalcitrant to antibiotic treatment, which leaves implant removal as the principal treatment option. In this book, we investigate the role of biofilms in breast and dental implant disease and cancer. We include in vitro models for investigating treatment of chronic wounds and disinfectant action against Candida sp. Also included are papers on the most recent strategies for treating biofilm infection ranging from antibiotics incorporated into bone void fillers to antimicrobial peptides and quorum sensing.

Medical microbiology. --- Medical bacteriology.

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Neonatal sepsis still remains a significant cause of morbidity and mortality in the newborn, particularly in preterm, low birth weight infants. Despite advances in neonatal care, overall case-fatality rates from sepsis may be as high as 50%. Clinical signs of bacterial infection are vague and non-specific, and up to now there exists no easily available, reliable marker of infection despite a large bulk of studies focussing on inflammatory indices in neonatology. Every neonatologist is faced with the uncertainty of under- or over- diagnosing bacterial infection. In this book three topics will be discussed: clinical presentation including a general approach to sepsis neonatorum and two distinct diagnoses pneumonia and osteomyelitis diagnostic approaches including C-reactive protein and the immature myeloid information, and prevention and treatment of bacterial infection with immunoglobulins.

Bacterial diseases. --- Bacterial infections --- Communicable diseases --- Medical bacteriology --- Pathogenic bacteria --- Neonatal medicine

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Pathogenic microorganisms, including fungi, oomycetes, bacteria, viruses, and viroids, constitute a serious threat to agriculture worldwide. In Spain, one of the countries with the highest proportion of agricultural gross domestic product in Europe, the agri-food industry is the main manufacturing activity. Consequently, the presence and emergence of microorganisms causing serious plant diseases to economically important crops is especially relevant. In line with this, Spain has an important number of research groups interested in plant pathology, with scientists working on many aspects of pathogenic microorganism-plant interactions, from the basic aspects to more applied studies. In recent years, numerous important advancements have been achieved by scientists working in Spain in terms of the biological and molecular characterization of plant pathogenic microorganisms, in elucidating mechanisms of microbe pathogenesis, plant resistance to microbe infection, and plant-microbe-vector interactions. All these new achievements have provided essential knowledge for agricultural researchers worldwide. The aim of this Special Issue was to provide a platform for Spanish researchers interested in plant pathogenic microorganisms to share their recent results related to microbe-plant host interactions, microbe-vector interactions, microbe-microbe interactions, evolution, ecology, and control strategies.

Pathogenic bacteria. --- Medical microbiology. --- Bacteria, Pathogenic --- Disease germs --- Bacteria --- Pathogenic microorganisms --- Bacterial diseases --- Medical bacteriology

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Bacterial pathogens have been becoming the main problem in hospital and community-acquired infections. It is hard to treat the strains that are resistant to antibiotics, due to the causing recurrent and untreatable infections. In recent years, the combination treatments and the novel technologies have been preferred to overcome the emergence of antibacterial resistance of pathogens. In this book, examples of pathogenesis by clinical cases, control by antibiotics and bioactive antimicrobials, control by novel technologies with the collection of up-to-date researches and reviews are presented. This book can be useful for researchers interested in antibacterials, bioactive compounds, and novel technologies.

Pathogenic bacteria. --- Bacteria, Pathogenic --- Disease germs --- Bacteria --- Pathogenic microorganisms --- Bacterial diseases --- Medical bacteriology --- Life Sciences --- Microbiology --- Genetics and Molecular Biology --- Biochemistry --- Bacteriology

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Bacterial diseases in animals. --- Swine --- Poultry --- Diseases. --- Communicable diseases in animals --- Veterinary bacteriology --- Poultry pests --- Bacterial diseases. --- Bacterial infections --- Communicable diseases --- Medical bacteriology --- Pathogenic bacteria