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This volume offers the latest tried and tested protocols for a range of detection methods, from the labs of the leading researchers in the field.

Mutation (Biology) --- Molecular genetics --- Chromosome abnormalities --- Chromosomal aberrations --- Chromosome anomalies --- Chromosomes --- Karyotypes --- Genetics --- Molecular biology --- Variation (Biology)

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As the largest group of extant vertebrates, fish offer an almost limitless number of striking examples of evolutionary adaptation to environmental and biotic selection pressure. The most diverse of all vertebrate groups, the higher taxa of fish traditionally have been classified by morphology and paleontology, with a much smaller input of cytogenetic information. DNA sequence data are exerting an increasingly strong influence on modern fish systematics, challenging the classification of numerous higher taxa ranging from genera to orders. The most fruitful approach, however, involves synthetic analyses of morphology, molecular phylogenetics, comparative karyology, and genome size. Karyotypes of more than 3400 species/subspecies are arranged here by fish systematics and include a list of genome size, sex chromosomes, B chromosomes, polyploidy, and locality of material fish, among others. This volume enables both beginners and advanced researchers to survey the existing literature and facilitates the implementation of an integrative approach to fish systematics. The first book on fish chromosomes in nearly 15 years, it is also the most comprehensive.

Fishes -- Classification -- Genetic aspects. --- Fishes -- Cytogenetics. --- Karyotypes -- Databases. --- Karyotypes. --- Fishes --- Karyotypes --- Vertebrates --- Biology --- Information Science --- Chordata --- Biological Science Disciplines --- Natural Science Disciplines --- Animals --- Disciplines and Occupations --- Eukaryota --- Organisms --- Classification --- Genetics --- Zoology --- Health & Biological Sciences --- Cytogenetics --- Genetic aspects --- Systematics --- Taxonomy --- Classifications --- Taxonomies --- Eucarya --- Eukarya --- Eukaryotes --- Eukaryotas --- Eukaryote --- Animalia --- Animal --- Metazoa --- Natural Sciences --- Physical Sciences --- Discipline, Natural Science --- Disciplines, Natural Science --- Natural Science --- Natural Science Discipline --- Physical Science --- Science, Natural --- Science, Physical --- Sciences, Natural --- Sciences, Physical --- Biologic Sciences --- Biological Science --- Science, Biological --- Sciences, Biological --- Biological Sciences --- Life Sciences --- Biologic Science --- Biological Science Discipline --- Discipline, Biological Science --- Disciplines, Biological Science --- Life Science --- Science Discipline, Biological --- Science Disciplines, Biological --- Science, Biologic --- Science, Life --- Sciences, Biologic --- Sciences, Life --- Chordates --- Chordate --- Information Sciences --- Science, Information --- Sciences, Information --- Vertebrate --- Fish --- Pisces --- Life sciences. --- Cell biology. --- Molecular ecology. --- Evolutionary biology. --- Animal genetics. --- Wildlife. --- Fish. --- Life Sciences. --- Animal Genetics and Genomics. --- Animal Systematics/Taxonomy/Biogeography. --- Evolutionary Biology. --- Fish & Wildlife Biology & Management. --- Molecular Ecology. --- Cell Biology. --- Evolution (Biology). --- Wildlife management. --- Cytology. --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Animal populations --- Game management --- Management, Game --- Management, Wildlife --- Plant populations --- Wildlife resources --- Natural resources --- Wildlife conservation --- Animal evolution --- Biological evolution --- Darwinism --- Evolutionary biology --- Evolutionary science --- Origin of species --- Evolution --- Biological fitness --- Homoplasy --- Natural selection --- Phylogeny --- Ecology --- Molecular biology --- Management --- Molecular aspects --- Animal systematics. --- Animal taxonomy. --- Aquatic animals --- Fisheries --- Fishing --- Ichthyology --- Animal classification --- Animal systematics --- Animal taxonomy --- Systematic zoology --- Systematics (Zoology) --- Taxonomy, Animal --- Zoological classification --- Zoological systematics --- Zoological taxonomy

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A reference to guide clinicians, researchers, teachers, and parents in identifying a range of genetic disorders despite widely variable cognitive, behavioral, and physical effects.

Chromosome abnormalities. --- Developmental disabilities -- Genetic aspects. --- Neurogenetics. --- Pediatric neuropsychology. --- Developmental disabilities --- Chromosome abnormalities --- Neurogenetics --- Pediatric neuropsychology --- Sex Chromosome Disorders --- Methods --- Heredodegenerative Disorders, Nervous System --- Diagnosis --- Genetic Diseases, Inborn --- Genetic Counseling --- Child --- Congenital, Hereditary, and Neonatal Diseases and Abnormalities --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Investigative Techniques --- Age Groups --- Chromosome Disorders --- Genetics, Medical --- Neurodegenerative Diseases --- Genetic Services --- Persons --- Nervous System Diseases --- Congenital Abnormalities --- Health Services --- Diseases --- Genetics --- Health Care Facilities, Manpower, and Services --- Named Groups --- Biology --- Biological Science Disciplines --- Health Care --- Natural Science Disciplines --- Disciplines and Occupations --- Pediatrics --- Medicine --- Health & Biological Sciences --- Genetic aspects --- Genetic aspects. --- Child neuropsychology --- Developmental neuropsychology --- Nervous system --- Chromosomal aberrations --- Chromosome anomalies --- Neuropsychology --- Pediatric neurology --- Neurosciences --- Chromosomes --- Karyotypes --- Mutation (Biology) --- Disabilities --- Developmentally disabled --- NEUROSCIENCE/General --- Introducción a la Psicobiología del Desarrollo (14102205) |x Bibliografía recomendada --- Enfant --- Développement --- Syndrome d'origine génétique --- Neuropsychopathologie --- développement --- trouble --- Developmental disabilities. --- Troubles du développement. --- Génétique

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Genetics --- Cell Transformation, Neoplastic --- Chromosome Aberrations --- Neoplasms --- Cancer --- Cancer genes --- Gènes du cancer --- genetics --- Genetic aspects --- Periodicals. --- Periodicals --- Aspect génétique --- Périodiques --- Cell Transformation, Neoplastic. --- Chromosome Aberrations. --- genetics. --- Genetic aspects. --- Abnormalities, Autosome --- Abnormalities, Chromosomal --- Abnormalities, Chromosome --- Chromosomal Aberrations --- Chromosome Abnormalities --- Cytogenetic Abnormalities --- Autosome Abnormalities --- Cytogenetic Aberrations --- Aberration, Chromosomal --- Aberration, Chromosome --- Aberration, Cytogenetic --- Aberrations, Chromosomal --- Aberrations, Chromosome --- Aberrations, Cytogenetic --- Abnormalities, Cytogenetic --- Abnormality, Autosome --- Abnormality, Chromosomal --- Abnormality, Chromosome --- Abnormality, Cytogenetic --- Autosome Abnormality --- Chromosomal Aberration --- Chromosomal Abnormalities --- Chromosomal Abnormality --- Chromosome Aberration --- Chromosome Abnormality --- Cytogenetic Aberration --- Cytogenetic Abnormality --- Chromosomes --- Cytogenetics --- Genetics, Medical --- Cytogenetic Analysis --- Neoplastic Cell Transformation --- Transformation, Neoplastic Cell --- Tumorigenic Transformation --- Neoplastic Transformation, Cell --- Cell Neoplastic Transformation --- Cell Neoplastic Transformations --- Cell Transformations, Neoplastic --- Neoplastic Cell Transformations --- Neoplastic Transformations, Cell --- Transformation, Cell Neoplastic --- Transformation, Tumorigenic --- Transformations, Cell Neoplastic --- Transformations, Neoplastic Cell --- Transformations, Tumorigenic --- Tumorigenic Transformations --- Cell Line, Transformed --- abnormalities --- Medical oncology --- Chemistry --- Health Sciences --- Life Sciences --- Biochemistry --- Clinical Medicine --- Oncology --- Genomics --- Cytogenetics. --- Medical oncology. --- periodicals --- periodicals. --- Aspect génétique --- Périodiques --- Cancer genetics --- Cancers --- Carcinoma --- Malignancy (Cancer) --- Malignant tumors --- Tumors --- Benign Neoplasms --- Malignancy --- Malignant Neoplasms --- Neoplasia --- Neoplasm --- Neoplasms, Benign --- Benign Neoplasm --- Malignancies --- Malignant Neoplasm --- Neoplasias --- Neoplasm, Benign --- Neoplasm, Malignant --- Neoplasms, Malignant --- Tumor --- Medical Oncology --- Chromosome abnormalities. --- Aberrations chromosomiques. --- Chromosomal aberrations --- Chromosome anomalies --- Karyotypes --- Mutation (Biology)

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Since the establishment of the DNA structure researchers have been highly interested in the molecular basis of the inheritance of genes and of genetic disorders. Scientific investigations of the last two decades have shown that, in addition to oncogenic viruses and signalling pathways alterations, genomic instability is important in the development of cancer. This view is supported by the findings that aneuploidy, which results from chromosome instability, is one of the hallmarks of cancer cells. Chromosomal instability also underpins our fundamental principles of understanding tumourigenesis: It thought that cancer arises from the sequential acquisition of genetic alterations in specific genes. In this hypothesis, these rare genetic events represent rate-limiting ‘bottlenecks’ in the clonal evolution of a cancer, and pre-cancerous cells can evolve into neoplastic cells through the acquisition of somatic mutations. This book is written by international leading scientists in the field of genome stability. Chapters are devoted to genome stability and anti-cancer drug targets, histone modifications, chromatin factors, DNA repair, apoptosis and many other key areas of research. The chapters give insights into the newest development of the genome stability and human diseases and bring the current understanding of the mechanisms leading to chromosome instability and their potential for clinical impact to the reader.

Cancer -- Genetic aspects. --- Chromosome abnormalities. --- Human genetics. --- Medical genetics. --- Molecular genetics. --- Mutation (Biology). --- Mutation (Biology) --- Chromosome abnormalities --- Cancer --- Genetics --- DNA Repair --- Genomic Instability --- Chromosome Aberrations --- Neoplasms --- Diseases --- Mutation --- Pathologic Processes --- Genetic Phenomena --- Biochemical Processes --- Genetic Processes --- Biology --- Biological Science Disciplines --- Genetic Variation --- Chemical Processes --- Phenomena and Processes --- Biochemical Phenomena --- Pathological Conditions, Signs and Symptoms --- Natural Science Disciplines --- Chemical Phenomena --- Disciplines and Occupations --- Pathology --- Cytology --- Medicine --- Health & Biological Sciences --- Genetic aspects --- Genetic aspects. --- Cancer genetics --- Chromosomal aberrations --- Chromosome anomalies --- Medicine. --- Cancer research. --- Cytogenetics. --- Laboratory medicine. --- Oncology. --- Cell biology. --- Biomedicine. --- Human Genetics. --- Laboratory Medicine. --- Cancer Research. --- Cell Biology. --- Cancer genes --- Chromosomes --- Karyotypes --- Variation (Biology) --- Oncology  . --- Medical laboratories. --- Cytology. --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Tumors --- Diagnosis, Laboratory --- Health facilities --- Laboratories --- Heredity, Human --- Human biology --- Physical anthropology --- Cancer research --- Clinical medicine --- Clinical pathology --- Diagnostic laboratory tests --- Laboratory diagnosis --- Laboratory medicine --- Medical laboratory diagnosis --- Diagnosis --- Cancer. --- Medical Genetics. --- Biomedical Research. --- Molecular Genetics. --- Cancer Biology. --- Research. --- Cancers --- Carcinoma --- Malignancy (Cancer) --- Malignant tumors --- Molecular biology --- Biological research --- Biomedical research --- Health Workforce --- Clinical genetics --- Heredity of disease --- Human genetics --- Medical sciences --- Genetic disorders