Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

The incidence of chronic inflammatory and autoimmune diseases is steadily increasing. Inflammatory bowel disease (IBD) is one example of a chronic inflammatory disease, which primarily affects the intestine but may also affect extraintestinal organs. The exact pathogenesis of IBD is currently unknown. However, it is clear that the pathogenesis is complex, involving barrier defects, changes in the intestinal microbiome, and chronic immune activation. This book aims to summarize basic aspects of these complex interactions between barrier function, microbiome, and the immune system. Of note, there is currently no cure for IBD. However, several therapies have evolved in the last years, which are overall able to-at least temporarily-suppress IBD. These therapies and the underlying mechanism are discussed.

Inflammatory bowel diseases. --- IBD (Disease) --- Inflammatory bowel disease --- Intestines --- Gastroenteritis --- Inflammation --- Medicine --- Hepatology --- Gastroenterology --- Health Sciences

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Inflammatory bowel disease is a chronic immune-mediated inflammation of the gastrointestinal tract of unknown origin, which includes Crohn's disease, ulcerative colitis, and inflammatory bowel disease of unclassified type. It is associated with different intestinal and extraintestinal manifestations like different neurological and psychiatric disorders. Histology is an important tool in the diagnosis and prognosis of inflammatory bowel disease and has an increasing part in patients' management. The objective of treatment is to make and keep long-lasting remission by immunosuppressive treatment like corticosteroids, thiopurines, and monoclonal antibodies directed against tumor necrosis factor alpha. Therapeutic drug monitoring of thiopurines by measuring levels of their metabolites has been proposed as a potentially effective tool in optimizing therapy in inflammatory bowel disease. Diets and their components influence microbiota of the intestine, function of the epithelial barrier, immune response, and other factors that have an important role in development and treatment of inflammation in the gut mucosa.

Inflammatory bowel diseases. --- Inflammatory bowel diseases --- IBD (Disease) --- Inflammatory bowel disease --- Intestines --- Gastroenteritis --- Inflammation --- Medicine --- Gastroenterology --- Health Sciences

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

The latest edition of this essential text provides a comprehensive overview of the unique pediatric issues of inflammatory bowel disease. Through new and thoroughly revised chapters, the volume features updates regarding pathogenesis, clinic features, and management, with an emphasis on recent understanding of pharmacokinetics and the utilization of cutting edge therapeutic monitoring to maximize efficacy of medical management. The new edition also highlights newer, recently approved drugs, emerging therapies, and the most recent recommendations regarding post-operative management for patients who ultimately require surgery.  Written by experts in the field, Pediatric Inflammatory Bowel Disease, Third Edition is a valuable resource for both pediatric and adult gastroenterologists involved in the care of children with inflammatory bowel disease.  .

Medicine. --- Gastroenterology. --- Medicine & Public Health. --- Inflammatory bowel diseases. --- IBD (Disease) --- Inflammatory bowel disease --- Intestines --- Inflammation --- Gastroenteritis --- Internal medicine --- Digestive organs --- Diseases --- Gastroenterology .

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Inflammatory bowel diseases --- Inflammatory Bowel Diseases --- Endoscopy, Gastrointestinal --- Endoscopic surgery --- diagnosis --- surgery --- methods --- IBD (Disease) --- Inflammatory bowel disease --- Intestines --- Gastroenteritis --- Inflammation

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Immune Mechanisms in Inflammatory Bowel Disease is a highly, concise update of the most recent advances in the immunobiology, genetics and microbiology related to Inflammatory Bowel Disease. This book broadly treats the topics that lead to understanding of the pathogenesis of this disease in an organized, systematic approach.

Inflammatory bowel diseases --- Gastrointestinal mucosa --- Immunological aspects. --- Pathogenesis. --- Immunology. --- Gastrointestinal system --- Mucous membrane --- IBD (Disease) --- Inflammatory bowel disease --- Intestines --- Gastroenteritis --- Inflammation --- Microbiology. --- Medical Microbiology. --- Immunobiology --- Life sciences --- Serology --- Microbial biology --- Biology --- Microorganisms --- Medical microbiology.