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Turmeric --- Common turmeric --- Curcuma domestica --- Curcuma longa --- Indian saffron --- Saffron, Indian --- Tumeric --- Curcuma --- Spices --- Therapeutic use.

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Turmeric --- Therapeutic use. --- Nervous system --- Curcumin --- Plant Extracts --- Nervous System Diseases --- Mental Disorders --- Diseases --- Chemotherapy. --- therapeutic use. --- drug therapy. --- Common turmeric --- Curcuma domestica --- Curcuma longa --- Indian saffron --- Saffron, Indian --- Tumeric --- Curcuma --- Spices --- Diferuloylmethane --- Turmeric yellow --- Yellow, Turmeric --- Antineoplastic agents --- Catechol --- Diarylheptanoids --- Dyes and dyeing --- Enzyme inhibitors --- Nonsteroidal anti-inflammatory agents --- Organs (Anatomy) --- Neurosciences

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Curcumin is derived from the root of the plant Curcuma longa (also called turmeric) and its medicinal uses have been described for over 5000 years. More than 1500 papers published within last half a century has revealed that curcumin has a potential in the treatment of wide variety of inflammatory diseases including cancer, diabetes, cardiovascular diseases, arthritis, Alzheimer, psoriasis etc, through modulation of numerous molecular targets. This is the first monograph to deal specifically with this subject.

Turmeric --- Therapeutic use. --- Common turmeric --- Curcuma domestica --- Curcuma longa --- Indian saffron --- Saffron, Indian --- Tumeric --- Curcuma --- Spices --- Immunology. --- Oncology. --- Emerging infectious diseases. --- Medical virology. --- Toxicology. --- Cancer Research. --- Infectious Diseases. --- Virology. --- Pharmacology/Toxicology. --- Chemicals --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Medical microbiology --- Virology --- Virus diseases --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Tumors --- Immunobiology --- Life sciences --- Serology --- Toxicology --- Cancer research. --- Infectious diseases. --- Pharmacology. --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemotherapy --- Drugs --- Pharmacy --- Microbiology --- Cancer research --- Physiological effect

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Turmeric has been used as a medicine, a condiment, and a dye since at least 600 B.C., while ginger has been used extensively throughout history for its medicinal purposes. The Agronomy and Economy of Turmeric and Ginger brings these two important plants together in one reference book, explaining their history, production techniques, and nutritional and medicinal properties in detail. This book is intuitively organized by plant and use, allowing quick access to information. It puts the uniquely Indian use and history of turmeric and ginger plants into a global context of produc

Turmeric --- Ginger --- Technology, Industry, and Agriculture --- Zingiberaceae --- Biological Products --- Complementary Therapies --- Technology, Industry, Agriculture --- Therapeutics --- Zingiberales --- Complex Mixtures --- Chemicals and Drugs --- Angiosperms --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Embryophyta --- Streptophyta --- Viridiplantae --- Plants --- Eukaryota --- Organisms --- Phytotherapy --- Plant Preparations --- Agriculture --- Curcuma --- Health & Biological Sciences --- Earth & Environmental Sciences --- Plant Sciences --- Pharmacy, Therapeutics, & Pharmacology --- Therapeutic use --- Economic aspects --- Therapeutic use. --- Economic aspects. --- Amomum zingiber --- Canton ginger --- Common ginger --- True ginger --- Zingiber officinale --- Zingiber officinalis --- Zingiber zingeber --- Zingiber zingiber --- Common turmeric --- Curcuma domestica --- Curcuma longa --- Indian saffron --- Saffron, Indian --- Tumeric --- Spices

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The plant-derived polyphenol curcumin has been used in promoting health and combating disease for thousands of years. Its therapeutic effects have been successfully utilized in Ayurvedic and Traditional Chinese Medicine in order to treat inflammatory diseases. Current results from modern biomolecular research reveal the modulatory effects of curcumin on a variety of signal transduction pathways associated with inflammation and cancer. In this context, curcumin’s antioxidant, anti-inflammatory, anti-tumorigenic, and even anti-metastatic activities are discussed. On the cellular level, the reduced activity of several transcription factors (such as NFkB or AP-1) and the suppression of inflammatory cytokines, matrix degrading enzymes, metastasis related genes and even microRNAs are reported. On functional levels, these molecular effects translate into reduced proliferative, invasive, and metastatic capacity, as well as induced tumor cell apoptosis. All these effects have been observed not only in vitro but also in animal models. In combination with anti-neoplastic drugs like Taxol, kinase inhibitors, and radiation therapy, curcumin potentiates the drugs’ therapeutic power and can protect against undesired side effects. Natural plant-derived compounds like curcumin have one significant advantage: They do not usually cause side effects. This feature qualifies curcumin for primary prevention in healthy persons with a predisposition to cancer, arteriosclerosis, or chronic inflammatory diseases. Nonetheless, curcumin is considered safe, although potential toxic effects stemming from high dosages, long-term intake, and pharmacological interactions with other compounds have yet to be assessed. This Special Issue examines in detail and updates current research on the molecular targets, protective effects, and modes of action of natural plant-derived compounds and their roles in the prevention and treatment of human diseases.

minerals --- cancer treatment --- chitosan --- n/a --- neurodegeneration --- antioxidant activity --- senescence --- tumor proliferation --- nanoparticles --- antimicrobial agents --- oxidative metabolites --- drug discovery --- Akt/mTOR signaling --- micronutrients --- ulcerative colitis --- transmission electron microscopy --- metabolic reprogramming --- curcumin --- death receptor --- chaperone-mediated autophagy --- wound healing --- brain ischemia --- autophagy --- Alzheimer’s disease --- genes --- transthyretin --- inflammatory bowel disease --- cellular pathway --- centrifugal partition chromatography --- nutrition --- amyloid --- Curcuma longa --- protein aggregation --- supportive care --- IL-17 --- senolytics --- complementary medicine --- macronutrients --- structure activity relationship --- gastroprotection --- Zingiberaceae --- anti-inflamation --- TLC bioautography --- microbiota --- glioblastoma multiforme --- amyloidosis --- SHMT2 --- antioxidants --- silica --- apoptosis --- reflux esophagitis --- gastric ulcer --- TLC-MS --- anti-cancer --- anticancer --- ImageJ --- anti-tumor --- delivery system --- wound --- Helicobacter pylori --- direct protein binding --- protein misfolding --- tumor growth --- diet --- Crohn’s disease --- hydrostatic counter-current chromatography --- ageing --- renal cell cancer --- gastric cancer --- amino-acids --- STAT3 --- mechanism of action --- inflamm-aging --- mitophagy --- necrotizing enterocolitis --- cell cycling --- vitamins --- turmeric tuber --- cancer --- tau protein --- Alzheimer's disease --- Crohn's disease