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Biomarkers and Biosensors offers thorough coverage of biomarker/biosensor interaction, current research trends, and future developments in applications of drug discovery. This book is useful to researchers in this field as well as clinicians interested in new developments in early detection and diagnosis of disease or the mode of operation of biomarkers. Biomarkers and Biosensors also emphasizes kinetics, and clearly delineates how this influences the biomarker market.Offers thorough coverage of the kinetics of biomarker interaction with the biosensor surfaceProvides evidence-based approach to
Pharmaceutical chemistry. --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry
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Originally published by Bentham and now distributed by Elsevier, Recent Advances in Medicinal Chemistry, Volume 1 covers leading-edge research and recent developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies. The fourteen updated reviews include unique experimental data and references, and each article highlights an important topic in current medicinal chemistry research. Topics covered include: aureolic acid group of anti-cancer
Pharmaceutical chemistry. --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry
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Pharmaceutical chemistry. --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry
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Pharmaceutical chemistry. --- Chemistry --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry
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Acteurs ou bénéficiaires, nous sommes tous spectateurs sidérés de l'ampleur des progrès de la médecine. Ils sont la conséquence des découvertes du XXe siècle, en particulier sur la biologie moléculaire et le génome. La recherche du XXIe siècle a ensuite pu bouleverser nos connaissances sur le fonctionnement du vivant au niveau moléculaire et sur l'extraordinaire ingéniosité des mécanismes moléculaires en jeu. Des spécialistes présentent et expliquent ces connaissances qui ont permis tant de réalisations thérapeutiques et ouvert tant de perspectives. On verra par exemple comment elles permettent d'identifier et de bloquer les effets nocifs des dysfonctionnements moléculaires, comme ceux qui conduisent à l'apparition de métastases dans les cancers. Tout ce qui est « molécule » est « chimie », et les collaborations entre biologie, médecine et chimie sont si essentielles que sans elles, rien ne serait arrivé. Cela est vrai pour les nouvelles thérapies, ainsi que pour la recherche pharmaceutique. Les méthodes d'analyse chimique ouvertes par le numérique (le criblage des molécules) lui donnent une efficacité presque inimaginable. La recherche fondamentale se traduit souvent par des innovations industrielles. L'apparition de l'inquiétant coronavirus (Covid-19) jette une lumière spectaculaire sur les besoins en nouvelles thérapies, avec l'objectif de vaccins et de traitements.
Pharmaceutical chemistry. --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry
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Recent advances in Medicinal Chemistry is a book series focused on leading-edge research on developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies. The series presents highly cited contributions first published in the impact factor journal Mini-Reviews in Medicinal Chemistry. Contributors to this volume have updated their work with new experimental data and references following their initial research. Each volume highlights a numbe
Pharmaceutical chemistry. --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry
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Pharmaceutical chemistry. --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry
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Pharmaceutical chemistry --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry --- Technique.
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This book reviews the latest advances and biomedical applications of nanozymes, which are artificial nanomaterials exhibiting enzymatic properties similar to natural enzymes, but with less limitations than natural enzymes. Nanozymes display advantages such as facile synthesis, easy surface modification, improved stability, higher catalytic power, and target-specific binding. Nanozymes containing metals, metal oxides, carbon, and metal sulfide are actually used for cancer therapy, biomolecules sensing, bioimaging, disease diagnostics and diabetes management. The book discloses underlying mechanisms, concepts, recent trends, constraints, and prospects for nanomedicine using nanozymes.
Pharmaceutical chemistry. --- Enzymes --- Biotechnology. --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry
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The crystalline state is the most commonly used as an essential solid in active pharmaceutical ingredients (API). The characterization of pharmaceutical crystals encompasses many scientific disciplines. Still, the core is crystal structure analysis, which reveals the molecular structure of essential pharmaceutical compounds. Crystal structure analysis provides important structural information related to the API's wide range of physicochemical properties, such as solubility, stability, tablet performance, color, and hygroscopicity. These properties should be understood in terms of molecular structures and interactions between molecules in crystals. Information on three-dimensional molecular structures also affords insights into the biological activity of molecules. The second reprint in the series, "Crystalline Pharmaceuticals (Volume II)" focused on the relationship between crystal structure and physicochemical properties. In particular, the new crystal structure of pharmaceutical compounds involving multi-component crystals, such as co-crystals, salts and hydrates, and polymorph crystals, were reported with interest. Such crystal structures contributed to the latest studies that combine morphology, spectroscopic, theoretical calculation, and thermal analysis with the crystallographic study. Thus, this reprint highlights the importance of crystal structure information in many areas of pharmaceutical science and presents current trends in the structure-property study of pharmaceutical crystals. The Guest Editors of this reprint hope the readers enjoy a wide variety of recent studies on "Crystalline Pharmaceuticals."
Pharmaceutical chemistry. --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry
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