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"With authoritative coverage of rare and common hemostatic disorders, Consultative Hemostasis and Thrombosis, 4th Edition, keeps you both up to date with all that's new in this fast-moving field as well as reviewing background and development and citing pertinent classical literature. Broad differential diagnoses are provided, underscoring the editors' position that correct treatment begins with correct diagnosis"--Publisher's description.

Blood coagulation disorders. --- Anticoagulants (Medicine) --- Blood platelet disorders. --- Fibrinolytic agents. --- Hemostasis --- Thrombosis --- Blood Coagulation Disorders. --- Blood Platelet Disorders. --- Fibrinolytic Agents --- Anticoagulants --- Physiological aspects. --- Pathophysiology. --- pathology. --- physiology. --- therapeutic use.

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Platelet function, or clot formation, is difficult to assess, but extremely important because inadvertent or excessive platelet activation underlies many common cardiovascular disorders, such as myocardial infarction, unstable angina, and stroke. In Platelet Function: Assessment, Diagnosis, and Treatment, a panel of leading researchers and clinicians review the latest findings on the complexities of platelet function and the various means of inhibiting platelet clot formation. The authors delineate an up-to-date picture of platelet biology and describe methods for assessing platelet function, including the commonly used platelet aggregation, thromboxane production, procoagulant function, platelet function under flow, and the expression of platelet activation markers. The focus is both on the technology and the outcome of research on platelets, including the fast developing fields of proteomics and genomics and their application to platelet research. The clinical applications of the various methods for the assessment of platelet function in vivo, as well as antiplatelet therapy, are fully discussed. Comprehensive and state of the art, Platelet Function: Assessment, Diagnosis, and Treatment offers vascular researchers and clinicians a sound foundation for understanding platelet biology, assessing thrombotic risk in patients, and determining the rational dosing of antiplatelet agents.

Blood platelet disorders --- Blood platelets --- Diagnosis. --- Examination. --- Thrombocytopathy --- Blood --- Diseases --- Cardiology. --- Heart --- Internal medicine

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Platelets have become an important research target for clinicians and basic scientists in a range of medical disciplines. This book reviews current science and applications in fields including thrombosis and hemostasis, signal transduction, and non-thrombotic conditions such as inflammation, allergy and tumor metastasis. It is a detailed, up-to-date, highly referenced text for clinical scientists and physicians, including recent developments in this rapidly expanding field. More than a scientific resource, this is also an authoritative reference and guide to the diagnosis and therapeutics of diseases involving platelets. Chapters are devised to provide a critical review of the most clinically relevant aspects of the subject. It will be an essential reference for biomedical scientists and clinicians in hematology, vascular medicine, cardiology, thrombosis and related disciplines.

Blood platelet disorders. --- Blood platelets --- Blood platelet receptors --- Platelet membrane receptors --- Platelet receptors --- Cell receptors --- Thrombocytopathy --- Blood --- Adhesiveness, Blood platelet --- Aggregation, Blood platelet --- Blood platelet aggregation --- Platelet adhesiveness --- Platelet aggregation --- Cell aggregation --- Receptors. --- Aggregation. --- Diseases --- Blood platelet disorders --- Blood Platelet Disorders --- Blood Platelets --- Platelet Aggregation Inhibitors --- Aggregation --- Receptors --- physiopathology --- drug effects --- pathology --- physiology --- therapeutic use

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PLATELETS is the definitive current source of state-of-the-art knowledge about platelets and covers the entire field of platelet biology, pathophysiology, and clinical medicine. Recently there has been a rapid expansion of knowledge in both basic biology and the clinical approach to platelet-related diseases including thrombosis and hemorrhage. Novel platelet function tests, drugs, blood bank storage methods, and gene therapies have been incorporated into patient care or are in development. This book draws all this information into a single, comprehensive and authoritative resource.

Blood platelet disorders. --- Blood platelets. --- Blood platelets --- Blood platelet disorders --- Blood Platelets --- Blood Platelet Disorders --- Hematologic Diseases --- Blood Cells --- Cells --- Hemic and Lymphatic Diseases --- Blood --- Hemic and Immune Systems --- Anatomy --- Diseases --- Physiology --- Human Anatomy & Physiology --- Health & Biological Sciences --- Anatomies --- Hemic System --- System, Hemic --- Water --- Cell --- Blood Corpuscles --- Blood Cell --- Blood Corpuscle --- Cell, Blood --- Cells, Blood --- Corpuscle, Blood --- Corpuscles, Blood --- Hematological Diseases --- Blood Diseases --- Blood Disease --- Disease, Blood --- Disease, Hematologic --- Disease, Hematological --- Diseases, Blood --- Diseases, Hematologic --- Diseases, Hematological --- Hematologic Disease --- Hematological Disease --- Thrombocytopathy --- Blood Platelet Disorder --- Disorder, Blood Platelet --- Disorders, Blood Platelet --- Platelet Disorder, Blood --- Platelet Disorders, Blood --- Thrombocytopathies --- Platelets --- Thrombocytes --- Blood Platelet --- Platelet --- Platelet, Blood --- Platelets, Blood --- Thrombocyte --- blood --- cytology --- Cell Biology --- Hematology --- Blood cells --- Megakaryocytes --- Blood Platlets. --- Blood Platelet Disorders. --- Blood Platelets.

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A rapid increase in our understanding of the biology of platelets and their role in disease in recent years has been paralleled by increasing successes with established platelet-modifying therapies in many clinical conditions. This text focuses on the clinical role of platelets in a wide variety of haematologic, cardiovascular and other disorders, providing a practical, clinically relevant handbook for all clinicians and researchers interested in platelets and their role in disease. Covering platelet physiology, bleeding disorders, thrombotic disorders and antithrombotic therapy. Chapters cover all the conventional and less conventional aspects of platelet involvement in disease, with an emphasis on recent clinical developments. Clear take home messages have been included in each chapter to aid clinical practice. With contributions from leading experts across three continents, Platelets in Hematologic and Cardiovascular Disorders is an up-to-date, well illustrated, practical resource for everyone involved in clinical practice with platelet disorders.

Blood platelets --- Blood --- Cardiovascular system --- Blood Platelets --- Cardiovascular diseases --- Clinical hematology --- Hematologic diseases --- Hematology --- Platelets --- Thrombocytes --- Blood cells --- Megakaryocytes --- Diseases --- pathology --- Blood platelets. --- Diseases. --- Hematologic Diseases --- Cardiovascular Diseases --- Blood Platelet Disorders --- physiopathology