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Mathematics --- #gsdbf --- #WBIB:dd.Lic.L.De Busschere --- 125 --- 510.3 --- 517.1 --- 510 --- Meetkunde --- Oneindigheid --- Tijd --- Wiskunde

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Ce livre est le quatrième d'une série d'ouvrages consacrés à une sélection d'organisations internationales, publiés sous l'égide de l'Institut Universitaire de Hautes Études Internationales et de la Società italiana per l'organizzazione internationale de Rome : les trois premiers titres sont L'Organisation pour l'Alimentation et l'Agriculture, Le Comité International de la Croix-Rouge et L'Organisation Internationale du Travail. Ce livre sur l'OMS est le premier ouvrage universitaire, non médical, en français, sur cette organisation mal connue. Il décrit et évalue non seulement le mandat, la structure et l'administration de l'OMS, mais également l'évolution de sa stratégie et ses principaux programmes. Il rappelle tout d'abord ses origines historiques, les conférences sanitaires internationales et les premières organisations internationales de santé publique. Sont ensuite examinés la naissance de l'OMS, ses objectifs principaux et l'évolution de sa stratégie, y compris le concept de « La santé pour tous d'ici l'An 2000 » et les critiques qui lui ont été apportées. L'évolution structurelle de l'Organisation, la composition ainsi que le fonctionnement des organes directeurs sont ensuite abordés. Les limites normatives de l'OMS sont analysées, avec l'exemple de la difficile adoption du Code international de commercialisation des substituts du lait maternel, ainsi que les relations de l'Organisation avec les ONG. Dans le cadre du rôle opérationnel de l'OMS, l'échec du Programme d'éradication du paludisme, la croisade victorieuse contre la variole et la lutte contre le SIDA et l'onchocercose sont donnés en exemple. Enfin, les questions budgétaires et financières, la coordination et la coopération avec les autres organisations, dont le PNUD, l'UNICEF, le FNUAP et les organisations humanitaires sont aussi exposées. La conclusion résume les défis auxquels l'OMS est confrontée, les critiques qui lui sont adressées et les réformes envisagées.

Hygiene. Public health. Protection --- World Health Organization --- World Health --- Public Health --- Health & Biological Sciences --- World Health Organization. --- 341.125 WHO --- AA / International- internationaal --- 341.15 --- Organisatie van de Verenigde Naties. --- Organisatie van de Verenigde Naties --- WHO. --- Wereldgezondheidsorganisatie --- World health organization --- droits humains --- santé --- politiques et pratiques du développement --- politique internationale --- OMS - Organisation mondiale de la santé

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Gottfried Wilhelm Leibniz verdiepte zich niet alleen in de filosofie, maar ook in de wiskunde, fysica, geologie, rechtswetenschap, geschiedenis en geneeskunde. Hij was ook actief als politicus en raadsheer aan het hof. Daarnaast ontwierp hij nieuwe soorten rijtuigen en drainagesystemen voor de mijnen in de Harz. Hij bedacht met succes een manier om fosfor te produceren. Hij organiseerde de verkoop van almanakken om de activiteiten van de Berlijnse Academie van Wetenschappen te bekostigen. en hij was de uitvinder van een van de eerste rekenmachines die in staat was de vier elementaire rekenoperaties uit te voeren. In deze biografie gaat de aandacht vooral uit naar drie aspecten die van fundamenteel belang zijn geweest voor zijn activiteiten als wetenschapper : de logica, de wiskunde en de fysica, in het bijzonder de dynamica. Daarnaast komen zijn onderzoekingen op het gebied van de geologie aan bod. Ook wordt het intrinsieke verband duidelijk tussen wetenschap en filosofie in Leibniz' opvattingen. Leibniz heeft een belangrijke stempel gedrukt op de vorming van ons hedendaags denken en de huidige mentaliteit. Computers, internet en de mathematisering van de logica zijn doordrenkt van een sterke leibniziaanse geest.

Leibniz, von, Gottfried W. --- 510 --- 51 <092> --- 1 LEIBNIZ, GOTTFRIED WILHELM --- #GGSB: Filosofie (17e eeuw) --- 51:93 --- biografieën --- wiskunde --- 155.2 --- Leibniz --- 125 --- Gottfried Wilhelm Leibniz --- Leibniz, Gottfried Wilhelm --- Wiskunde --- 510 Fundamental and general considerations of mathematics. Foundations, logic etc. --- Fundamental and general considerations of mathematics. Foundations, logic etc. --- 1 LEIBNIZ, GOTTFRIED WILHELM Filosofie. Psychologie--LEIBNIZ, GOTTFRIED WILHELM --- Filosofie. Psychologie--LEIBNIZ, GOTTFRIED WILHELM --- 51 <092> Mathematics--Biografieën --- Mathematics--Biografieën --- Werken over wijsgeren ; afzonderlijk --- Filosofie --- Geschiedenis --- Biografieën --- 17e eeuw --- Biografie --- Oudheid --- Boekdrukkunst --- Film (cinematografie) --- Literatuur --- China --- Geneeskunde --- Techniek (wetenschap) --- Romeinse Rijk --- Hellenisme --- Griekenland --- Hellas --- Atlas --- Museum --- Noorwegen --- Film --- Muziek --- Schilderkunst --- Tekenkunst --- Kafka, Franz --- Vlaanderen --- Vlaams --- Emigratie --- Vrouw --- Filosofie (17e eeuw)

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Geophysical, environmental, and urban fluid flows (i.e., flows developing in oceans, seas, estuaries, rivers, aquifers, reservoirs, etc.) exhibit a wide range of reactive and transport processes. Therefore, identifying key phenomena, understanding their relative importance, and establishing causal relationships between them is no trivial task. Analysis of primitive variables (e.g., velocity components, pressure, temperature, concentration) is not always conducive to the most fruitful interpretations. Examining auxiliary variables introduced for diagnostic purposes is an option worth considering. In this respect, tracer and timescale methods are proving to be very effective. Such methods can help address questions such as, "where does a fluid-born dissolved or particulate substance come from and where will it go?" or, "how fast are the transport and reaction phenomena controlling the appearance and disappearance such substances?" These issues have been dealt with since the 19th century, essentially by means of ad hoc approaches. However, over the past three decades, methods resting on solid theoretical foundations have been developed, which permit the evaluation of tracer concentrations and diagnostic timescales (age, residence/exposure time, etc.) across space and time and using numerical models and field data. This book comprises research and review articles, introducing state-of-the-art diagnostic theories and their applications to domains ranging from shallow human-made reservoirs to lakes, river networks, marine domains, and subsurface flows

residence time --- Three Gorges Reservoir --- tributary bay --- density current --- water level regulation --- marina --- water renewal --- transport timescales --- return-flow --- macro-tidal --- wind influence --- floating structures --- San Francisco Estuary --- Sacramento–San Joaquin Delta --- water age --- transport time scales --- hydrodynamic model --- tidal hydrodynamics --- stable isotopes --- reactive tracers --- tailor-made tracer design --- hydrogeological tracer test --- kinetics --- partitioning --- Mahakam Delta --- age --- exposure time --- return coefficient --- CART --- source water fingerprinting --- floodplain --- turbulence --- ADCP measurement --- wave bias --- Reynolds stress --- transport process --- passive tracers --- terrestrial dissolved substances --- Pearl River Estuary --- shallow lake --- meteorological influence --- sub-basins --- Delft3D --- partial differential equations --- boundary conditions --- geophysical and environmental fluid flows --- reactive transport --- interpretation methods --- diagnostic timescales --- age distribution function --- radionuclide --- tracer --- data collection --- antimony 125 (125Sb) --- tritium (3H) --- dispersion --- modeling --- English Channel --- North Sea --- Biscay Bay --- timescale --- transport --- hydrodynamic --- ecological --- biogeochemical --- coastal --- estuary --- flushing time --- shallow reservoir --- numerical modeling --- Lagrangian transport modelling --- coupled wave–ocean models --- ocean drifters --- wave-induced processes --- model skills --- n/a --- Sacramento-San Joaquin Delta --- coupled wave-ocean models

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Radiopharmaceuticals are used in the diagnosis and treatment of various diseases, especially cancer. In general, radiopharmaceuticals are either salts of radionuclides or radionuclides bound to biologically active molecules, drugs, or cells. Tremendous progress has been made in discovering, developing, and commercializing numerous radiopharmaceuticals for the imaging and therapy of cancer. Significant research is ongoing in academia and the pharmaceutical industry to develop more novel radiolabeled compounds as potential radiopharmaceuticals for unmet needs. This Special Issue aims to focus on all aspects of the design, characterization, evaluation, and development of novel radiolabeled compounds for the diagnosis and treatment of cancer and the application of new radiochemistry and methodologies for the development of novel radiolabeled compounds. Outstanding contributions presented in this Special Issue will significantly add to the field of radiopharmaceuticals.

positron emission tomography (PET) --- pyrazoles --- fluorine-18 --- radionuclides --- PET probes --- imaging pharmaceuticals --- hypopharyngeal cancer --- 188Re-liposome --- repeated therapy --- NGS --- microRNA --- aprepitant --- radiopharmaceuticals --- neurokinin 1 receptor antagonist --- radionuclide chelators --- kidney uptake --- cleavable linkers --- neutral endopeptidase (NEP) --- renal brush border enzymes --- prostate-specific membrane antigen (PSMA) --- cancer imaging and therapy --- somatostatin analogs --- radiolabeling --- radionuclide therapy --- imaging --- adrenergic receptor --- positron emission tomography --- radiotracer --- cholecystokinin-2 receptor --- minigastrin --- molecular imaging --- targeted radiotherapy --- lutetium-177 --- EpCAM --- radionuclide --- SPECT --- iodine --- PIB --- breast --- cancer --- PET --- target-specific biomolecules --- immunoPET imaging pharmaceuticals --- production processes --- 124I-labeled monoclonal antibodies --- radiotracers --- AAZTA --- scandium-44 --- FAP --- SA --- DPP --- PREP --- radioiodine labeling --- radioiodination --- biomolecules --- peptides --- proteins --- monoclonal antibodies --- 123,124,125,131I-labeled molecules and biomolecules --- n/a