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Over the last thirty years, the foremost inspiration for research on metastasis, cancer recurrence, and increased resistance to chemo- and radiotherapy has been the notion of cancer stem cells.The twenty-eight chapters assembled in Cancer Stem Cells - The Cutting Edge summarize the work of cancer researchers and oncologists at leading universities and hospitals around the world on every aspect of cancer stem cells, from theory and models to specific applications (glioma), from laboratory research on signal pathways to clinical trials of bio-therapies using a host of devices, from solutions to laboratory problems to speculation on cancers' stem cells' evolution. Cancer stem cells may or may not be a subset of slowly dividing cancer cells that both disseminate cancers and defy oncotoxic drugs and radiation directed at rapidly dividing bulk cancer cells, but research on cancer stem cells has paid dividends for cancer prevention, detection, targeted treatment, and improved prognosis.

Cancer cells. --- Cells --- Pathology, Cellular --- Oncology

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In The Evolution of Death, the follow-up to Becoming Immortal: Combining Cloning and Stem-Cell Therapy, also published by SUNY Press, Stanley Shostak argues that death, like life, can evolve. Observing that literature, philosophy, religion, genetics, physics, and gerontology still struggle to explain why we die, Shostak explores the mystery of death from a biological perspective.Death, Shostak claims, is not the end of a linear journey, static and indifferent to change. Instead, he suggests, the current efforts to live longer have profoundly affected our ecological niche, and we are evolving into a long-lived species. Pointing to the artificial means currently used to prolong life, he argues that as we become increasingly juvenilized in our adult life, death will become significantly and evolutionarily delayed. As bodies evolve, the embryos of succeeding generations may be accumulating the stem cells that preserve and restore, providing the resources necessary to live longer and longer. If trends like this continue, Shostak contends, future human beings may join the ranks of other animals with indefinite life spans.

Life Expectancy --- Evolution. --- Aging. --- Death. --- Life expectancy. --- Expectancy of life --- Expectation of life --- Life spans (Biology) --- Vital statistics --- Premature death --- Death --- Dying --- End of life --- Life --- Terminal care --- Terminally ill --- Thanatology --- Age --- Ageing --- Senescence --- Developmental biology --- Gerontology --- Longevity --- Age factors in disease --- Cardiac Death --- Determination of Death --- End Of Life --- End-Of-Life --- Near-Death Experience --- Death, Cardiac --- Fatal Outcome --- Aging, Biological --- Biological Aging --- Mutation Accumulation --- trends. --- Philosophy --- Physiological effect