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Book
Antibodies : applications and new development
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Year: 2012 Publisher: [Saif Zone, Sharjah, U.A.E] ; Oak Park, IL : Bentham Science,

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Antibodies Applications and New Developments is an overview of the current developments of techniques and methods relating to immunodiagnostics and immunoanalysis. This e-book also deals with specialties in the fields of drug, pesticide, antigen and food contaminant detection.


Book
Monoclonal antibodies
Authors: ---
ISBN: 1280374802 9786610374809 0585483566 9780585483566 Year: 2000 Publisher: Oxford New York Oxford University Press

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Monoclonal Antibodies: A Practical Approach covers the preparation, testing, derivation, and applications of monoclonal antibodies. New immunological techniques incorporating tried and tested methodologies are described, making the book of interest to established and inexperienced immunologists. Both the standard somatic hybridization technique and recombinant techniques, including the use of phage libraries, for the preparation of rodent and human monoclonal antibodies are described. Protocols for both the small and large scale production are detailed, as well as purification and labelling (with both radioisotopes and non-radioisotopes) methods. The applications of monoclonal antibodies in immunoblotting, enzyme linked immunoassays, immunofluorescence, and FACS analysis are all covered in detail. Finally protocols are given for the use of monoclonal antibodies in rheumatoid arthritis, tissue typing, detecting DNA modified during chemotherapy, and in the clinical analysis of transplantation samples for malignancy. This book will therefore be an invaluable laboratory companion to anyone using monoclonal antibodies in their research.


Book
Autoantibodies
Author:
ISBN: 1536109932 9781536109931 9781536109771 1536109770 Year: 2017 Publisher: New York, NY

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This book provides new research on types and roles of autoantibodies. Chapter One analyses autoantibodies in diabetes. Chapter Two discusses the role of autoantibodies towards TNF in patients with rheumatoid arthritis and bronchial asthma. Chapter Three examines new findings on immunoglobulin E in eosinophilic granulomatosis with polyangiitis.--


Periodical
Antibodies.
Year: 2012 Publisher: Basel, Switzerland : MDPI AG,

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Book
Trends in immunolabelled and related techniques
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ISBN: 9535152882 9535105701 Year: 2012 Publisher: IntechOpen

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The book is coined to provide a professional insight into the different trends of immunoassay and related techniques. It encompasses 22 chapters which are grouped into two sections. The first section consists of articles dealing with emerging uni-and-multiplex immunolabelled methods employed in the various areas of research. The second section includes review articles which introduce the researchers to some immunolabelled techniques which are of vital significance such as the use of the conjugates of the Staphylococcus aureus protein "A" and the Streptococcus Spps. protein "G" in immunolabelled assay systems, the use of bead-based assays and an overview on the laboratory assay systems. The book provides technological innovations that are expected to provide an efficient channel for developments in immunolabelled and related techniques. It is also most useful for researchers and post-graduate students, in all fields, where immunolabelled techniques are applicable.


Book
Structure, Isotypes, Targets, and Post-Translational Modifications of Immunoglobulins and Their Role in Infection, Inflammation and Autoimmunity
Authors: --- ---
Year: 2020 Publisher: Frontiers Media SA

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact


Book
The Lock and Key of Medicine
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ISBN: 9780300213522 0300213522 9780300167733 0300167733 Year: 2015 Publisher: New Haven [Connecticut] London

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The untold story of monoclonal antibodies-the molecular heroes of biotechnology that revolutionized the diagnosis and treatment of more than fifty major diseases This book is the first to tell the extraordinary yet unheralded history of monoclonal antibodies. Often referred to as Mabs, they are unfamiliar to most nonscientists, yet these microscopic protein molecules are everywhere, quietly shaping our lives and healthcare. Discovered in the mid-1970s in the laboratory where Watson and Crick had earlier unveiled the structure of DNA, Mabs have radically changed understandings of the pathways of disease. They have enabled faster, cheaper, and more accurate clinical diagnostic testing on a vast scale. And they have played a fundamental role in pharmaceutical innovation, leading to such developments as recombinant interferon and insulin, and personalized drug therapies such as Herceptin. Today Mabs constitute six of the world's top ten blockbuster drugs and make up a third of new introduced treatments. Lara V. Marks recounts the risks and opposition that a daring handful of individuals faced while discovering and developing Mabs, and she addresses the related scientific, medical, technological, business, and social challenges that arose. She offers a saga of entrepreneurs whose persistence and creativity ultimately changed the healthcare landscape and brought untold relief to millions of patients. Even so, as Marks shows, controversies over Mabs remain, and she examines current debates over the costs and effectiveness of these innovative drugs.

Immunoassay : a survey of patents, patent applications and other literature, 1980-1991
Authors: --- ---
ISBN: 0429080689 1482286823 1280139110 9786610139118 6610139113 0203974883 9780203974889 9781851668663 1851668667 1851668667 9781482286823 Year: 1992 Publisher: London : Elsevier Applied Science,

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"This book presents the results of a comprehensive study of literature on patents, patent applications and other literature, such as journal articles. The survey covers literature published from the United States, Japan and Western Europe between January 1980 and April 1991."--Provided by publisher.


Book
Autoantibodies
Authors: ---
ISBN: 9781620815885 1620815885 9781620815601 1620815605 Year: 2012 Publisher: [Hauppauge] New York

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Antigenic variation
Authors: ---
ISBN: 1423755383 9781423755388 9780121948511 012194851X 128100815X 9781281008152 0080475884 9780080475882 9786611008154 Year: 2003 Publisher: Amsterdam, Netherlands : Academic Press,

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The topic of antigenic variation is important in both biology and medicine. It is of enormous interest, as it describes the process(es) whereby microorganisms 'shift shape', by genetic rearrangement or otherwise. In medical terms, this has a major impact on the infectious disease process, since the immune system has great difficulty in keeping up with this variation, and thus eliminating the infectious agent. Antigenic variation is a major method by which microbes evade the immune response, and persist in the body.The broad scope of the book appeals to all those working in the field of in

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