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Atopic Dermatitis is a common disease characterized by inflamed, itching and dry skin. This relapsing allergic disorder has complex etiology and shows a remarkably high clinical heterogeneity which complicates the diagnosis and clinical management. This book is divided into 4 sections. The first section (Disease Etiology) describes some of the physiological mechanisms underlying Atopic Dermatitis, including alterations in the immune system and the skin-barrier function. The important role of host-microorganism interactions on the pathophysiology of Atopic Dermatitis is discussed in the second section (Microorganisms in Atopic Dermatitis). An overview of the clinical diagnostic criteria and the disease management protocols commonly used is given in the third section (Diagnosis and Clinical Management). The last section (New Treatments) describes new therapeutic approaches that are not widely used but are currently being studied due to preliminary evidence showing a clinical benefit for Atopic Dermatitis.

Atopic dermatitis. --- Epidemiology. --- Diseases --- Public health --- Atopic eczema --- Eczema, Atopic --- Allergy --- Skin --- Inflammation --- Epidemiology & medical statistics

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Hand eczema is a major complaint worldwide and a frequent occupational disorder. This book provides a comprehensive and detailed overview of the classification, etiology, diagnosis, prevention, and therapy of hand eczema. It is innovative, up to date, and practical. The links with particular occupations are explained, the various diagnostic tests are presented, and the role of different topical and systemic treatments is clearly described. The authors are world leaders in the field. The Textbook of Hand Eczema reflects a new era in hand dermatitis and will be invaluable for all who deal with the condition in their clinical practice.

Eczema --- Hand --- Diseases. --- Skin --- Inflammation --- Dermatology. --- Medicine --- Diseases

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This book presents the state of the art in research into atopic dermatitis, or atopic eczema, and provides numerous effective practical management recommendations that are grounded in the immense clinical experience of the author. A scientific evidence-based approach to the subject is adopted, progressing from clinical symptoms in different disease stages, molecular genetics, and pathophysiology through to treatment and prevention. All aspects of patient management are covered, including diagnostics, avoidance strategies, emollient therapy, and acute treatment of eczema and itch. Diverse special therapeutic approaches are discussed, ranging from glucocorticoids, topical calcineurin inhibitors, and antimicrobial therapy through to UV therapy, allergen-specific immunotherapy, systemic immunosuppressive therapy, and emerging options. Environmental influences are considered, and there is a focus on the whole human being, with attention to psychosocial aspects of the disease and the benefit of educational programs such as “eczema schools”. Atopic Dermatitis will be invaluable for dermatologists, allergists, pediatricians, and general practitioners and informative for other interested persons and sufferers.  .

Dermatology --- Medicine --- Health & Biological Sciences --- Atopic dermatitis. --- Eczema. --- Atopic eczema --- Eczema, Atopic --- Skin --- Allergy --- Inflammation --- Dermatology. --- Allergy. --- Allergology. --- Allergic diseases --- Allergies --- Hypersensitivity --- Hypersensitivity, Immediate --- Immediate allergy --- Immediate hypersensitivity --- Immunologic diseases --- Immunoglobulin E --- Diseases

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L’esigenza di chiarire i concetti attuali dell’atopia, che per troppo tempo hanno oscillato tra una primitiva visione squisitamente clinica ed una successiva unicamente immunologica, era matura da tempo. L’avere compreso che il ruolo delle immunoglobuline E non è esaustivo ed avere accettato la salomonica divisione tra atopia intrinseca ed estrinseca, sono stati i primi due passi fondamentali. Le recenti scoperte del ruolo dell’immunità innata, e quindi dei peptidi antimicrobici, hanno aperto dei fondamentali spazi di comprensione nell’atopia e non solo. Quello che ora appare chiaro è che l’atopia non è la malattia di un organo ma piuttosto un difetto delle membrane che delimitano il nostro "self". Il fatto che queste membrane si chiamino pelle, intestino, congiuntiva, bronchi o quant’altro ha artificialmente frammentato la comprensione ed il trattamento di un fenomeno unitario. Questo libro vuole cercare di fare una sintesi delle diverse esperienze ma soprattutto essere uno stimolo a far sì che la medicina si focalizzi costruttivamente sullo stesso bersaglio. Se così sarà, non assisteremo più a"guerre di religione" tra scienziati e medici pratici o, peggio ancora, tra i differenti specialisti che si contendono il paziente. Se l’atopia, come noi crediamo, è un problema globale, esso può essere adeguatamente affrontato solo in un contesto pluridisciplinare e in clima collaborativo, non solo tra medico e medico ma anche tra medico e paziente.

Atopic dermatitis --- Treatment. --- Prevention. --- Atopic eczema --- Eczema, Atopic --- Allergy --- Skin --- Inflammation --- Dermatology. --- Allergy. --- Immunology. --- Allergology. --- Allergic diseases --- Allergies --- Hypersensitivity --- Hypersensitivity, Immediate --- Immediate allergy --- Immediate hypersensitivity --- Immunologic diseases --- Immunoglobulin E --- Medicine --- Immunobiology --- Life sciences --- Serology --- Diseases

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Atopic eczema (atopic dermatitis, neurodermitis diffusa, endogenous eczema) is one of the most common skin diseases of our time and is still increasing in prevalence dramatically all over the world. The reasons for this increase are not known. It occurs at any age, not only in childhood, approximately 2/3 of children affected will suffer from this disease when they are grown-up. Written by leading experts of their field, this second edition comprises the state of the art in pathophysiology, clinical medicine and therapeutic management. It demonstrates that there is no simple "miracle" cream, pill or diet for this disease, but that a disturbed barrier function can only be repaired by adequate and individualized skin care and it shows how unspecific anti-inflammatory treatment has to be individually tailored according to body area affected, patient age and acuity of skin lesions. All physicians will find this book most helpful in the painstaking search for the individual causal or eliciting factors.

Atopic dermatitis. --- Eczema. --- Skin --- Atopic eczema --- Eczema, Atopic --- Allergy --- Inflammation --- Dermatology. --- Allergy. --- Immunology. --- Medicine, Industrial. --- Allergology. --- Occupational Medicine/Industrial Medicine. --- Industrial medicine --- Medicine, Occupational --- Occupational medicine --- Medicine --- Occupational diseases --- Immunobiology --- Life sciences --- Serology --- Allergic diseases --- Allergies --- Hypersensitivity --- Hypersensitivity, Immediate --- Immediate allergy --- Immediate hypersensitivity --- Immunologic diseases --- Immunoglobulin E --- Diseases --- Occupational medicine.