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Therapeutic regimens for visceral leishmaniasis (also Kala-azar, Dum-dum fever or black fever), caused by parasitic protozoa of the Leishmania genus, evolve at a pace never seen before. Spread by tiny and abundant sand flies, the parasite infects internal organs and bone marrow and if left untreated will almost always result in the death of the host. In developing countries successful diagnosis and treatment are complicated by asymptomatic cases, undernutrition and Kala-azar/HIV co-infections. This book brings together world-renown experts writing state-of-arts review on the progress in diagnosis and treatment of visceral leishmaniasis, ultimately leading to the complete elimination of this fatal disease from South Asia. The chapters provide valuable information for disease control as well as therapy and the diagnostic improvements necessary for early treatment, subclinical detection and drug-resistant cases. The presented methods allow for points-of-care testing in the endemic area, enabling rapid detection in resource-poor settings with easy handling and low costs.  This book provides essential information for scientists, medical practitioners and policy makers involved in the diagnosis, treatment and elimination of Kala-azar.

Parasitology. --- Drug resistance. --- Veterinary medicine. --- Laboratory medicine. --- Nephrology. --- Drug Resistance. --- Veterinary Medicine/Veterinary Science. --- Laboratory Medicine.

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In questo volume vengono descritti i numerosi aspetti della patologia delle api con prospettive diverse e molteplici, tali da raggiungere destinatari diversi: l’apicoltore, il tecnico addetto all’assistenza sanitaria, il veterinario, il naturalista, il ricercatore, lo studente. Accanto alle nozioni più aggiornate, infatti, sono sempre presenti un gran numero di indicazioni operative. A un livello tecnico-scientifico vengono affrontate tutte le patologie conosciute delle api e, più in generale, le problematiche sanitarie dell’apicoltura: dall’epidemiologia alla normativa, dalle avversità ambientali ai residui nei prodotti dell’alveare. Le indicazioni tecniche, soprattutto nel campo della profilassi, rendono questo volume particolarmente interessante anche dal punto di vista pratico, anche grazie a un apparato iconografico particolarmente ricco.

Bees --- Diseases. --- Entomology. --- Veterinary medicine. --- Veterinary Medicine/Veterinary Science. --- Farriery --- Large animal medicine --- Large animal veterinary medicine --- Livestock medicine --- Veterinary science --- Medicine --- Animal health --- Animals --- Domestic animals --- Livestock --- Insects --- Zoology --- Diseases --- Losses

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This Open Access book brings together authoritative voices in animal and environmental ethics, who address the many different facets of changing human-animal relationships in the Anthropocene. As we are living in complex times, the issue of how to establish meaningful relationships with other animals under Anthropocene conditions needs to be approached from a multitude of angles. This book offers the reader insight into the different discussions that exist around the topics of how we should understand animal agency, how we could take animal agency seriously in farms, urban areas and the wild, and what technologies are appropriate and morally desirable to use regarding animals. This book is of interest to both animal studies scholars and environmental ethics scholars, as well as to practitioners working with animals, such as wildlife managers, zookeepers, and conservation biologists.

Veterinary medicine --- Philosophy --- Ethics & moral philosophy --- The environment --- Zoology & animal sciences --- Veterinary Medicine/Veterinary Science --- Philosophy of Nature --- Ethics --- Environment, general --- Zoology --- Animal Ethics --- Moral Philosophy and Applied Ethics --- Environmental Sciences --- Environmental Ethics --- Anthropocene --- Animal Agency --- Gene Technology

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This volume reviews the current understanding of the taxonomy, disease syndromes, genetics, biology, and pathogenic factors of Histophilus somni, as well as the host immune response to this pathogen. H. somni is one of the most important bacterial pathogens in cattle and other ruminants, and its virulence factors are highly conserved with Haemophilus influenzae and other members of the Pasteurellaceae. H. somni has been recognized as a major cause of thrombotic meningoencephalitis, respiratory disease syndromes, myocarditis, reproductive disease syndromes, polyarthritis, mastitis, ocular disease, and septicemia. The only known habitats of H. somni are the mucosal surfaces of ruminants, making this bacterium an opportunistic pathogen. Although it is capable of causing inflammation at systemic sites and is toxic to epithelial and phagocytic cells, the bacterium’s wide array of virulence factors act primarily as a defense against, or to escape recognition from, host innate and adaptive immunity.

Microbiology & Immunology --- Biology --- Health & Biological Sciences --- Bacterial diseases in animals. --- Communicable diseases in animals --- Veterinary bacteriology --- Microbiology. --- Veterinary medicine. --- Bacteriology. --- Medical Microbiology. --- Veterinary Medicine/Veterinary Science. --- Microbiology --- Farriery --- Large animal medicine --- Large animal veterinary medicine --- Livestock medicine --- Veterinary science --- Medicine --- Animal health --- Animals --- Domestic animals --- Livestock --- Microbial biology --- Microorganisms --- Diseases --- Losses --- Medical microbiology.

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Biofilms are implicated in many common medical problems including urinary tract infections, catheter infections, middle-ear infections, dental plaque, gingivitis, and some less common but more lethal processes such as endocarditis and infections in cystic fibrosis.  However, the true importance of biofilms in the overall process of disease pathogenesis has only recently been recognized. Bacterial biofilms are one of the fundamental reasons for incipient wound healing failure in that they may impair natural cutaneous wound healing and reduce topical antimicrobial efficiency in infected skin wounds.  Their existence explains many of the enigmas of microbial infection and a better grasp of the process may well serve to establish a different approach to infection control and management.   Biofilms and their associated complications have been found to be involved in up to 80% of all infections.  A large number of studies targeted at the bacterial biofilms have been conducted, and many of them are referred to in this book, which is the first of its kind.   These clinical observations emphasize the importance of biofilm formation to both superficial and systemic infections, and the inability of current antimicrobial therapies to ‘cure’ the resulting diseases even when the in vitro tests suggest that they should be fully effective. In veterinary medicine the concept of biofilms and their role in the pathogenesis of disease has lagged seriously behind that in human medicine.  This is all the more extraordinary when one considers that much of the research has been carried out using veterinary species in experimental situations.   The clinical features of biofilms in human medicine is certainly mimicked in the veterinary species but there is an inherent and highly regrettable indifference to the failure of antimicrobial therapy in many veterinary disease situations, and this is probably at its most retrograde in veterinary wound management.  Biofilms and Veterinary Medicine is specifically focused on discussing the concerns of biofilms to health and disease in animals and provides a definitive text for veterinary practitioners, medical and veterinary students, and researchers.

Veterinary bacteriology --- Bacterial diseases in animals --- Biofilms --- Veterinary medicine --- Veterinary therapeutics --- Biology --- Health & Biological Sciences --- Veterinary Medicine --- Microbiology & Immunology --- Biofilms. --- Veterinary medicine. --- Farriery --- Large animal medicine --- Large animal veterinary medicine --- Livestock medicine --- Veterinary science --- Life sciences. --- Microbiology. --- Bacteriology. --- Life Sciences. --- Veterinary Medicine. --- Medicine --- Animal health --- Animals --- Domestic animals --- Livestock --- Diseases --- Losses --- Microbial aggregation --- Microbial ecology --- Veterinary Medicine/Veterinary Science. --- Microbial biology --- Microorganisms --- Microbiology