Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Marine habitats are promising sources to identify novel organisms and compounds. A total of 70% of the planet’s surface is covered by ocean, and little is known about the biosphere within these habitats. In the last few years, numerous novel bioactive compounds or secondary metabolites from marine environments have been described. This is, and will be, a promising source of candidate compounds in pharma research and chemical biology. In recent years, a number of novel techniques have been introduced to the field and it has become easier to actually (bio-)prospect compounds such as enzyme inhibitors. Those novel compounds then need to be characterized and evaluated in comparison to well-known representatives. This Special Issue focuses on the description of novel enzyme inhibitors of marine origin, including bioprospecting, omic approaches, and structural and mechanistic aspects.

sponge Monanchora pulchra --- pentacyclic guanidine alkaloids --- GH36 α-galactosidase --- GH109 α-N-acetylgalactosaminidase --- slow-binding irreversible inhibitor --- monanchomycalin B --- monanhocidin A --- normonanhocidin A --- Alzheimer′s disease --- BACE1 --- acetylcholinesterase --- in silico docking --- phlorotannins --- Ulva intestinalis --- ACE inhibitory peptide --- optimization --- purification --- structural identification --- molecular docking --- secondary metabolites --- Mycosphaerella sp. --- asperchalasine --- α-glucosidase --- kinase inhibitors --- drug development --- marine natural products --- inhibitor --- macroalgae --- marine fish --- protease --- Ulva ohnoi --- functional annotation --- structure–function relation --- natural products --- bioactives --- enzyme inhibition --- inactivation --- marine bacteria --- marine fungi --- marine sponges

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This book entitled Marine Algal Antioxidants, as a special issue of the Antioxidants journal, encloses eleven scientific articles with a preface written by the two editors, Christophe Brunet and Clementina Sansone. Marine Algal Antioxidants book reports advances of the research on marine photosynthetic organisms for the growth of biotechnological pipelines aimed to enhance antioxidant molecules production by algae. More than twenty scientists share the results of their research and highlight the relevance of algae for developing marine biotechnology products to flourish the requirements of nutraceuticals or cosmeceuticals in the defense of human health. Multidisciplinarity of the scientific approaches presented in this book – such as physiological, molecular, chemistry, technical or technological methodologies – lays the foundation for harmonizing the links between them towards the unique goal of the improvement of marine algal factory processes.

algae --- Chlorella --- Fucus --- detoxification --- environmental pollution --- antioxidants --- heavy metals --- selenium --- SOD-1 --- neurotoxicology --- aminoazuphrates --- clinical medicine --- nutrition --- neuropathology --- Dunaliella salina --- microalgae --- red LED --- blue LED --- growth --- carotenoids --- plastoquinol:oxygen oxidoreductase --- photosynthesis --- antioxidant activities --- Box–Behnken design --- microwave-assisted extraction --- polysaccharide --- Ulva pertusa --- seaweed --- 9-cis β-carotene --- all-trans β-carotene --- light intensity --- isomerisation --- light --- ascorbic acid --- phenolic compounds --- flavonoids --- photoprotection --- Phaeodactylum tricornutum --- fucoxanthin --- antioxidative --- antiproliferative --- antioxidant --- biodiversity --- genome–scale metabolic networks (GSMNs), data integration --- brown algae --- oxygenated carotenoid biosynthesis --- abscisic acid --- Saccharina japonica --- Cladosiphon okamuranus --- lipophilic antioxidant --- solvent blending --- macroalgae --- LC-ESI-MS/MS --- carotenoid pigment --- anthocyanin --- chlorophyll derivative --- phototrophic --- heterotrophic --- Scenedesmus --- chlorophylls --- hydroxy-chlorophyll --- oxidative metabolism --- ROS --- lactone-chlorophyll --- photoacclimation --- seaweeds --- green algae --- marine algae --- Ulva intestinalis --- Enteromorpha intestinalis --- quantification --- polyphenols --- apigenin --- accelerated solvent extraction --- ASE --- HPLC-LRMS --- HPLC-HRMS --- HPLC --- TPC --- Folin–Ciocalteu --- TFC --- qNMR --- n/a --- Box-Behnken design --- genome-scale metabolic networks (GSMNs), data integration --- Folin-Ciocalteu

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

The marine environment is considered one of the most important sources of natural bioactive compounds with extremely rich biodiversity. Marine glycans are remarkable molecules, playing a determinant role in biological processes. Marine сarbohydrate-containing substances have drawn increasing attention in the field of biomedicine for their various biological activities, such as antitumor, antivirus, hypoglycemic, immunomodulatory, and anticoagulant. These compounds obtained from marine sources, such as algae, microbes, and animals, are usually biodegradable and biocompatible, and exhibit biological properties that contribute to the discovery of a wide range of new bioactive substances with special pharmacological properties of interest to medicine. Carbohydrate-based compounds include glycans, glycoproteins, proteoglycans, glycolipids, and low-molecular and complex glycosides of differential origin. Many of the polysaccharides allow for loading lower drug dosages, which may lead to a drastic reduction of the side effects caused by the drugs. In addition, the structure of polysaccharides can be relatively easily modified in order to synthesize derivatives with desirable characteristics for drug delivery. Complexes on the basis of carbohydrates are often prepared to improve their functional properties. In this Special Issue, we seek to contribute to the discussion of various aspects of marine carbohydrate-containing compounds and provide a unique platform for a new concept for their use in medicine in order to continue to facilitate further research in this area.

chitosan-gentamicin conjugate --- antimicrobial --- anti-inflammatory --- scald repair --- sulfated polysaccharides --- galactans --- green seaweed --- NMR --- immunostimulation --- inflammatory mediators --- carrageenan --- lipopolysaccharide --- macromolecular structure --- nonspecific resistance to lipopolysaccharide --- cytokines --- enteric infections --- salmonellosis --- glyceroglycolipid metabolism --- phosphate starvation --- transcriptome --- glyceroglycolipid homeostasis --- chitosan --- polyelectrolyte complex --- cytokine --- nitric oxide --- anti-inflammatory activity --- Ulva pertusa --- polysaccharides --- colitis --- antioxidant --- exopolysaccharide --- structure --- Vibrio alginolyticus --- Epidermist --- chitosan oligosaccharides --- inflammation cytokines --- intestine --- oxidative status --- oxidative stress --- Porphyridium marinum --- high pressure homogenizer --- antibacterial activity --- anti-biofilm activity --- anti-cancer activity --- alginate lyase --- cold-adapted --- exo/endo-type --- Alteromonas portus --- oligosaccharide --- antioxidant activity --- exopolysaccharides --- scandium --- theranostic --- cancer cell lines --- proliferation --- laminarin --- fucoidan --- gastrointestinal tract --- microbiome --- swine --- post-weaning --- antibiotic alternatives --- n/a

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

In this thesis, Matthias Heydt applies digital in-line holography to achieve for the first time a complete three dimensional and real time motion analysis of Ulva zoospores, both in solution and in the vicinity of different surfaces. These results provide previously unknown information about the behavior and mechanism spores use to select a suitable site for settlement. This work gives deeper insight into biofouling algae and stimulates new design strategies for antifouling coatings. Furthermore, the tracking system developed during this research could be used as a new system for assessing the antifouling performance on different surfaces at very early points in time, allowing disentanglement of surface conditioning and interaction of spores with pristine chemistries.

Freshwater ecology. --- Freshwater phytoplankton. --- Marine ecology. --- Marine phytoplankton. --- Chemistry --- Physical Sciences & Mathematics --- Physical & Theoretical Chemistry --- Zoospores. --- Ulva. --- Cells. --- Lettuce, Sea --- Sea lettuce --- Fungi --- Zoospores --- Chemistry. --- Physical chemistry. --- Microbial ecology. --- Spectroscopy. --- Microscopy. --- Environmental engineering. --- Biotechnology. --- Physical Chemistry. --- Optics, Lasers, Photonics, Optical Devices. --- Microbial Ecology. --- Environmental Engineering/Biotechnology. --- Spectroscopy and Microscopy. --- Organisms --- Cytology --- Ulvaceae --- Spores --- Chemistry, Physical organic. --- Chemical engineering --- Genetic engineering --- Environmental microbiology --- Microorganisms --- Ecology --- Microbiology --- Chemistry, Physical organic --- Chemistry, Organic --- Chemistry, Physical and theoretical --- Lasers. --- Photonics. --- Analysis, Microscopic --- Light microscopy --- Micrographic analysis --- Microscope and microscopy --- Microscopic analysis --- Optical microscopy --- Optics --- Analysis, Spectrum --- Spectra --- Spectrochemical analysis --- Spectrochemistry --- Spectrometry --- Spectroscopy --- Chemistry, Analytic --- Interferometry --- Radiation --- Wave-motion, Theory of --- Absorption spectra --- Light --- Spectroscope --- Environmental control --- Environmental effects --- Environmental stresses --- Engineering --- Environmental health --- Environmental protection --- Pollution --- Sustainable engineering --- New optics --- Light amplification by stimulated emission of radiation --- Masers, Optical --- Optical masers --- Light amplifiers --- Light sources --- Optoelectronic devices --- Nonlinear optics --- Optical parametric oscillators --- Chemistry, Theoretical --- Physical chemistry --- Theoretical chemistry --- Qualitative --- Analytical chemistry

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

The term “algae” refers to a large diversity of unrelated phylogenetic entities, ranging from picoplanktonic cells to macroalgal kelps. Marine algae are an important primary producer in the marine food chain, responsible for the high primary production of coastal areas, providing food resources in situ for many grazing species of gastropods, peracarid crustaceans, sea urchins or fish. Recent findings indicate that marine environments have rapidly changed due to global warming over the past several decades. This change has led to significant variations in marine algal ecology. For example, a long-term increase in ocean temperatures due to global warming has facilitated the intensification of harmful algal blooms, which adversely impact public health, aquatic organisms, and aquaculture industries. Thus, extensive studies have been conducted, but there is still a gap in our understanding of the variation in their ecology in accordance with future marine environmental changes. To fill this gap, studies on the taxonomy and ecology of marine algae are highly necessary. We have invited algologists to submit research articles that enable us to advance our understanding of the taxonomy and ecology of marine algae. Fourteen papers have been collected so far, which cover different aspects of the taxonomy and ecology of marine algae, including understudied species, interspecific comparisons, and new techniques.

Ulva prolifera --- Bacillus sp. --- allelopathy --- photosynthetic system --- reactive oxygen species (ROS) --- antioxidative system --- Chlorella vulgaris --- cold-tolerant --- PUFAs (polyunsaturated fatty acids) --- calorific value --- Cystoseira --- algal cartography --- abrasion platforms --- SE Mediterranean --- phylogeny supertree --- DNA sequencing --- harmful algal blooms --- brown tide --- life history --- Aureococcus anophagefferens --- resting stage cell --- Karlodinium --- trophic modes --- phagotrophy --- mixotrophy --- Scrippsiella --- resting cyst --- intercalary plate --- precingular plate --- ribotype --- Tetraselmis suecica --- associated bacterial community --- free-living bacteria --- particle associated bacteria --- Bacillus nitratireducens --- fermentation broth --- polyaluminum chloride coagulation (PAC) --- Gymnodinium catenatum --- cysts --- sub-fossil diatom --- sediment --- Suncheonman Bay --- new record --- Bysmatrum --- cyst --- eyespot --- morphology --- lagoon --- new record diatoms --- taxonomic --- ecological --- habitat --- Acrochaetioid --- Colaconema formosanum --- COI-5P --- Endophytic alga --- Nemaliophycidae --- rbcL --- taxonomy --- harmful algae --- molecular detection --- monitoring --- Jeju coastal waters --- Changjiang --- southwestern Yellow Sea --- outbreak mechanisms --- wind anomaly --- n/a