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Obesity and type 2 diabetes are increasing worldwide problems. In this book we reviewed insulin secretion in both healthy individuals and in patients with type 2 diabetes. Because of the risk associated with progression from insulin resistance to diabetes and cardiovascular complications increases along a continuum, we included several chapters on the damage of endothelial cells in type 2 diabetes and genetic influences on endothelial cell dysfunction. Cardiovascular complications occur at a much lower glucose levels, thus a review on the oral glucose tolerance test compared to other methods was included. The medical conditions associated with type 2 diabetes such as pancreatic cancer, sarcopenia and sleep disordered breathing with diabetes were also discussed. The book concludes with several chapters on the treatments for this disease offering us hope in prevention and successful alleviation of the co-morbidities associated with obesity and type 2 diabetes.
Type 2 diabetes. --- Adult onset diabetes --- Ketosis resistant diabetes --- Maturity onset diabetes --- NIDDM (Diabetes) --- Non-insulin-dependent diabetes --- Noninsulin-dependent diabetes --- Stable diabetes --- Type II diabetes --- Diabetes --- Endocrinology
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Non-insulin-dependent diabetes. --- Dementia. --- Non-insulin-dependent diabetes --- Prevention. --- Adult onset diabetes --- Ketosis resistant diabetes --- Maturity onset diabetes --- NIDDM (Diabetes) --- Noninsulin-dependent diabetes --- Stable diabetes --- Type II diabetes --- Diabetes --- Aphrenia --- Aphronesia --- Athymia --- Dementias --- Brain --- Neurobehavioral disorders --- Psychoses --- Diseases --- Type 2 diabetes. --- Type 2 diabetes
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Obesity and type 2 diabetes are increasing worldwide problems. In this book we reviewed factors that contribute to glucose homeostasis and the pathogenesis of Type 2 diabetes. In addition the book addresses current strategies for treatment of Type 2 Diabetes.
Type 2 diabetes --- Treatment. --- Adult onset diabetes --- Ketosis resistant diabetes --- Maturity onset diabetes --- NIDDM (Diabetes) --- Non-insulin-dependent diabetes --- Noninsulin-dependent diabetes --- Stable diabetes --- Type II diabetes --- Diabetes --- Endocrinology
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Type 2 diabetes "mellitus" affects nearly 120 million persons worldwide- and according to the World Health Organization this number is expected to double by the year 2030. Owing to a rapidly increasing disease prevalence, the medical, social and economic burdens associated with the microvascular and macrovascular complications of type 2 diabetes are likely to increase dramatically in the coming decades. In this volume, leading contributors to the field review the pathogenesis, treatment and management of type 2 diabetes and its complications. They provide invaluable insight and share their discoveries about potentially important new techniques for the diagnosis, treatment and prevention of diabetic complications.
Endocrinology. --- Type 2 diabetes. --- Diabetes --- Complications. --- Pathogenesis. --- Adult onset diabetes --- Ketosis resistant diabetes --- Maturity onset diabetes --- NIDDM (Diabetes) --- Non-insulin-dependent diabetes --- Noninsulin-dependent diabetes --- Stable diabetes --- Type II diabetes --- Internal medicine --- Hormones --- Complications and sequelae --- Patogenez --- Endocrinology
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"Medicinal Foods as Potential Therapies for Type-2 Diabetes: The Chemical and Pharmacological Basis of their Action is the first book to focus on active pharmacological principles that modulate diabetes, associated risk factors, and complications and the mechanism of action of widely used anti-diabetic herbal plants, rather than the nutritional composition of the foods. It provides up-to-date information on the scientific basis of some acclaimed antidiabetic super fruits, species and other food ingredients. The global incidence of diabetes and its major risk factor, obesity, is growing with epidemic proportion, and so there is growing interest in finding new drugs from natural and synthetic sources to help halt this epidemic. The book is divided into six sections: the first part addresses fact and figures of diabetes and obesity at global level. In the second part, the physiological control of carbohydrate and lipid metabolism as well as some common therapeutic targets are presented. In section 3, the pathophysiology of type-2 diabetes and therapeutic options are presented. A dedicated section on super fruits include the therapeutic potential of bilberry and blueberries, bitter melon, okra, prickly pear cactus and other fruits that gain importance as antidiabetic agents in recent years. In section 5, the chemistry and pharmacology of spices including cinnamon, cloves, fenugreek, garlic, ginger and turmeric are presented to outline their antidiabetic potential. The last section includes beverages such as tea, coffee and yerba mate as well as a dedicated chapter on food supplements and other food products with emerging antidiabetic potential. Medicinal Foods as Potential Therapies for Type-2 Diabetes: The Chemical and Pharmacological Basis of their Action is invaluable research scientists and students in medical and pharmaceutical sciences, medicinal chemistry, herbal medicine, drug discovery/development, nutrition science as well as herbal practitioners, industries from the nutraceutical and pharmaceutical areas, and organizations dealing with diabetes and obesity managements"--
Diabetes --- Diet therapy. --- Non-insulin-dependent diabetes --- Diabetes Mellitus, Type 2 --- Functional Food --- diet therapy. --- analysis. --- Adult onset diabetes --- Ketosis resistant diabetes --- Maturity onset diabetes --- NIDDM (Diabetes) --- Noninsulin-dependent diabetes --- Stable diabetes --- Type II diabetes --- Type 2 diabetes
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Non-insulin-dependent diabetes --- Diabetes in women. --- Women --- Adult onset diabetes --- Ketosis resistant diabetes --- Maturity onset diabetes --- NIDDM (Diabetes) --- Noninsulin-dependent diabetes --- Stable diabetes --- Type II diabetes --- Type 2 diabetes --- Diabetes --- Complications. --- Diseases
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Over the last twenty years, type 2 diabetes skyrocketed to the forefront of global public health concern. In this text, Mari Armstrong-Hough examines the rise in and response to the disease in two societies: the United States and Japan.
Non-insulin-dependent diabetes --- Adult onset diabetes --- Ketosis resistant diabetes --- Maturity onset diabetes --- NIDDM (Diabetes) --- Noninsulin-dependent diabetes --- Stable diabetes --- Type II diabetes --- Type 2 diabetes --- Diabetes --- Social aspects --- Treatment
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Metabolism --- Mitochondria. --- Disorders. --- Obesity. --- Non-insulin-dependent diabetes. --- Mitochondrial pathology. --- Diabetes Mellitus, Type 2 --- Obesity --- Metabolic Syndrome --- Mitochondria --- etiology. --- prevention & control. --- etiology --- physiology. --- Mitochondrial disorders --- Pathology, Cellular --- Disorders of metabolism --- Metabolic diseases --- Metabolic disorders --- Metabolism, Disorders of --- Diseases --- Adult onset diabetes --- Ketosis resistant diabetes --- Maturity onset diabetes --- NIDDM (Diabetes) --- Noninsulin-dependent diabetes --- Stable diabetes --- Type II diabetes --- Type 2 diabetes --- Diabetes --- Adiposity --- Corpulence --- Fatness --- Overweight --- Body weight --- Nutrition disorders --- Pathology --- Disorders --- Non-insulin-dependent diabetes --- Type 2 diabetes.
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Diagnosing and managing type 2 diabetes constitutes a tremendous challenge to the primary care provider confronting a rapidly growing patient population and a multiplicity of new scientific insights and therapeutic strategies. In Type 2 Diabetes, Pre-Diabetes, and the Metabolic Syndrome: The Primary Care Guide to Diagnosis and Management, Ronald A. Codario, MD-a well-known and highly respected authority on diabetes in private practice for over 30 years-details for today's busy primary care practitioners the state-of-the-art in diagnosing and managing diabetes as well as in reducing patient risk factors. Using an evidence-based approach, Dr. Codario explains, in simple clinical terms that avoid the complexity of much larger textbooks, our latest understanding of the pathophysiology of diabetes, its treatment with insulin and oral agents, and the management of its risk factors. The author also extensively reviews such major topics as the metabolic syndrome, the role of exercise and nutrition, and the key issues associated with the use of herbs and nutraceuticals. Illustrative case studies in diabetes management, an outstanding bibliography of suggested readings, and extensive chapter subheadings for quick reference make this book a practical, easy-to-read guide for physicians dealing with this killer disease. A value-added compact disk contains a companion e-book version of the book for downloading and use in the reader's PC or PDA. Also included are continuing medical education (CME) questions that provide the opportunity to acquire up to a maximum of 10 AMA/PRA category 1 CME credits. For the past 15 years, the author has given CME lectures on diabetes throughout the country. State of the art and highly practical, Type 2 Diabetes, Pre-Diabetes, and the Metabolic Syndrome: The Primary Care Guide to Diagnosis and Management offers practitioners an authoritative, well-honed approach to the successful management of their diabetic patients.
Primary Health Care. --- Diabetes Mellitus, Type 2. --- Prediabetic State. --- Insulin resistance. --- Primary care (Medicine) --- Non-insulin-dependent diabetes. --- Soins de santé primaires --- Diabète non insulinodépendant --- Primary care (Medicine). --- Non-insulin-dependent diabetes --- Insulin resistance --- Prediabetic State --- Primary Health Care --- Diabetes Mellitus, Type 2 --- Diabetes Mellitus --- Comprehensive Health Care --- Patient Care Management --- Glucose Metabolism Disorders --- Endocrine System Diseases --- Metabolic Diseases --- Health Services Administration --- Diseases --- Nutritional and Metabolic Diseases --- Health Care --- Clinical Endocrinology --- Medicine --- Health & Biological Sciences --- Primary medical care --- Insulin tolerance --- Resistant diabetes --- Resistance to insulin --- Adult onset diabetes --- Ketosis resistant diabetes --- Maturity onset diabetes --- NIDDM (Diabetes) --- Noninsulin-dependent diabetes --- Stable diabetes --- Type II diabetes --- Type 2 diabetes --- Medicine. --- General practice (Medicine). --- Diabetes. --- Medicine & Public Health. --- General Practice / Family Medicine. --- Medical care --- Diabetes --- Hormone resistance --- Insulin antibodies --- Complications --- Family medicine. --- Family practice (Medicine) --- General practice (Medicine) --- Physicians (General practice) --- Brittle diabetes --- Diabetes mellitus --- IDDM (Disease) --- Insulin-dependent diabetes --- Ketosis prone diabetes --- Type 1 diabetes --- Carbohydrate intolerance --- Endocrine glands --- Diabetic acidosis --- Glycosylated hemoglobin
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The prevalence of obesity has dramatically increased in western and westernized societies, making the disease the second leading cause of unnecessary deaths in the US. Obesity results from imbalanced metabolic regulation leading to excessive lipid storage. As important novel entities in metabolic regulation, taste receptors and their cells are critical elements that adapt the gustatory system to metabolic signals and vice versa. The role of taste receptor genes in gastrointestinal tissues, as well as their dynamic regulation in gustatory and non-gustatory tissues in response to metabolic cues, has become the focus of an entirely new and rapidly developing research field with impacts on fuel sensing, metabolic control, and ingestive behavior. This book reflects the recent scientific progress in the field of fuel sensing in the mouth, GI tract, and brain and examines the olfactory bulb as a potential metabolic sensor and the brain-gut endocrine axis. It also touches on relevant novel molecular and cellular mechanisms regulating lipid storage and metabolism and covers the identification and functional characterization of obesity genes. Lastly, it illustrates the use of insect models to study relevant problems of energy homeostasis.
Bioenergetics. --- Chemoreceptors. --- Energy metabolism -- Regulation. --- Lipids -- Metabolism. --- Non-insulin-dependent diabetes -- Animal models. --- Obesity -- Animal models. --- Metabolism --- Chemoreceptors --- Bioenergetics --- Lipids --- Obesity --- Non-insulin-dependent diabetes --- Metabolic Phenomena --- Neurons, Afferent --- Peripheral Nervous System --- Overweight --- Overnutrition --- Nutrition Disorders --- Neurons --- Phenomena and Processes --- Body Weight --- Nervous System --- Energy Metabolism --- Sensory Receptor Cells --- Cells --- Body Size --- Signs and Symptoms --- Nutritional and Metabolic Diseases --- Anatomy --- Pathological Conditions, Signs and Symptoms --- Diseases --- Body Weights and Measures --- Body Constitution --- Physiological Phenomena --- Physical Examination --- Diagnostic Techniques and Procedures --- Diagnosis --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Human Anatomy & Physiology --- Biology --- Health & Biological Sciences --- Cytology --- Physiology --- Regulation --- Animal models --- Obesity. --- Research. --- Disorders. --- Adiposity --- Corpulence --- Fatness --- Disorders of metabolism --- Metabolic diseases --- Metabolic disorders --- Metabolism, Disorders of --- Anabolism --- Catabolism --- Metabolism, Primary --- Primary metabolism --- Life sciences. --- Cell biology. --- Life Sciences. --- Cell Biology. --- Body weight --- Nutrition disorders --- Biochemistry --- Disorders --- Cytology. --- Cell biology --- Cellular biology --- Cytologists
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