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Book
The blood-brain barrier : new research
Authors: ---
ISBN: 1621008126 9781621008125 9781621007661 1621007669 Year: 2012 Publisher: Hauppauge, N.Y. : Nova Science Publishers,


Book
Physiology, pharmacology and pathology of the blood-brain barrier
Authors: ---
ISBN: 3030996530 3030996549 Year: 2022 Publisher: Cham, Switzerland : Springer,


Book
Advanced Blood-Brain Barrier Drug Delivery
Author:
ISBN: 3036564160 3036564179 Year: 2023 Publisher: [Place of publication not identified] : MDPI AG,

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Abstract

This Special Issue of Pharmaceutics, "Advanced Blood-Brain Barrier Drug Delivery," comprises 16 articles or reviews, which cover a cross-section of brain drug delivery for either small-molecule or large-molecule therapeutics.

Handbook of Neurochemistry and Molecular Neurobiology : Neural Membranes and Transport
Author:
ISBN: 0387303804 0387303472 Year: 2007 Publisher: New York, NY : Springer US : Imprint: Springer,


Book
Vascular Mechanisms in CNS Trauma
Authors: --- --- ---
ISBN: 1461486890 1461486904 Year: 2014 Publisher: New York, NY : Springer New York : Imprint: Springer,

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Abstract

Vascular Mechanisms in CNS Trauma focuses on the vascular aspects of brain and spinal cord trauma.  Twenty nine chapters are arranged in three sections—Molecular Mechanisms; Experimental Models and Methods; and Clinical Challenges and Opportunities.  The first section addresses topics in the basic biology of brain and spinal cord trauma, ranging from the pathophysiology of cerebral endothelial cells and gliovascular interactions to the role of stem cells in neurovascular repair. The second section covers experimental methods in rodent and in large animal models of CNS injury, as well as the use of biomaterials and biomarkers in studying the mechanisms of tissue response. The third section deals with clinical issues in the monitoring and treatment of the patient with traumatic injury of the brain and spinal cord. Contributors to the book include an integrated mix of basic scientists and clinicians from diverse institutions. By presenting salient issues in CNS trauma from a vascular perspective, this book should make a unique contribution to the understanding of traumatic brain and spinal cord injury.


Book
Nanotechnology methods for neurological diseases and brain tumors : drug delivery across the blood-brain barrier
Authors: --- ---
ISBN: 0128038004 0128037962 9780128038000 9780128037966 Year: 2017 Publisher: London, [England] : Academic Press,


Book
Nanotechnology-based targeted drug delivery systems for brain tumors
Authors: ---
ISBN: 0128122498 0128122188 9780128122495 9780128122181 Year: 2018 Publisher: London : Academic Press, an imprint of Elsevier,


Book
Molecular Physiology and Metabolism of the Nervous System
Author:
ISBN: 019932283X 1280595574 9786613625403 0199838224 0195394275 9780195394276 9780199838226 9781280595578 Year: 2012 Publisher: New York Oxford University Press

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Abstract

The molecular basis for the physiology of the brain has advanced enormously in the past twenty years with an influx of new information gleaned through technological developments in neuroimaging and molecular discoveries. Molecular Physiology and Metabolism of the Nervous System, authored by Gary A. Rosenberg, an authority on the physiology of brain fluids and metabolism, combines the classic physiology that dates back to the beginning of the nineteenth century with the advances in molecular sciences, providing a strong framework for understanding the diseases that are commonly treated by neuro


Book
The Blood Brain Barrier (BBB)
Authors: --- ---
ISBN: 3662437872 3662437864 Year: 2014 Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer,

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Abstract

Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.


Book
Biology and Regulation of Blood‑Tissue Barriers
Author:
ISBN: 1461447100 1461447119 Year: 2013 Publisher: New York, NY : Springer New York : Imprint: Springer,

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Abstract

This book was written by many outstanding investigators who have spent decades to study different aspects of blood‑tissue barrier function. They have summarized some of the latest and fascinating development in their fields of research including the blood‑brain barrier, the blood‑retinal barrier, the gut barrier, the blood‑biliary barrier, the blood‑follicle barrier, the blood‑epididymis barrier, the blood‑testis barrier, the tight junction barrier in general as well as barriers in the female reproductive tract. Included are also chapters that focus on topics that are physiologically applicable to all blood‑tissue barriers. Many of these chapters also include information on specific human diseases, such as pathological changes of the gut barrier that cause bowel disorders resulting from inflammation of the epithelial lining in the intestine, and infertility in men as a result of disruption of the blood‑epididymal and/or blood‑testis barriers; and on new therapeutic approaches (e.g., drug delivery across the blood‑brain and the blood‑retinal barriers).

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