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Blood-brain barrier. --- Blood-cerebral barrier --- Blood-cerebrospinal fluid barrier --- Brain-blood barrier --- Hemato-encephalic barrier --- Hematoencephalic barrier --- Brain --- Cerebrospinal fluid --- Choroid plexus --- Blood-vessels
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Blood-brain barrier. --- Blood-cerebral barrier --- Blood-cerebrospinal fluid barrier --- Brain-blood barrier --- Hemato-encephalic barrier --- Hematoencephalic barrier --- Brain --- Cerebrospinal fluid --- Choroid plexus --- Blood-vessels --- Barrera hematoencefàlica --- Farmacologia
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This Special Issue of Pharmaceutics, "Advanced Blood-Brain Barrier Drug Delivery," comprises 16 articles or reviews, which cover a cross-section of brain drug delivery for either small-molecule or large-molecule therapeutics.
Blood-brain barrier. --- Blood-cerebral barrier --- Blood-cerebrospinal fluid barrier --- Brain-blood barrier --- Hemato-encephalic barrier --- Hematoencephalic barrier --- Brain --- Cerebrospinal fluid --- Choroid plexus --- Blood-vessels
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Blood-brain barrier. --- Biological transport. --- Molecular neurobiology. --- Molecular neurology --- Nervous system --- Molecular biology --- Neurobiology --- Membrane transport --- Passive transport, Biological --- Physiological transport --- Transport, Biological --- Diffusion --- Osmosis --- Blood-cerebral barrier --- Blood-cerebrospinal fluid barrier --- Brain-blood barrier --- Hemato-encephalic barrier --- Hematoencephalic barrier --- Brain --- Cerebrospinal fluid --- Choroid plexus --- Molecular aspects --- Blood-vessels --- Neurosciences. --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences
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Vascular Mechanisms in CNS Trauma focuses on the vascular aspects of brain and spinal cord trauma. Twenty nine chapters are arranged in three sections—Molecular Mechanisms; Experimental Models and Methods; and Clinical Challenges and Opportunities. The first section addresses topics in the basic biology of brain and spinal cord trauma, ranging from the pathophysiology of cerebral endothelial cells and gliovascular interactions to the role of stem cells in neurovascular repair. The second section covers experimental methods in rodent and in large animal models of CNS injury, as well as the use of biomaterials and biomarkers in studying the mechanisms of tissue response. The third section deals with clinical issues in the monitoring and treatment of the patient with traumatic injury of the brain and spinal cord. Contributors to the book include an integrated mix of basic scientists and clinicians from diverse institutions. By presenting salient issues in CNS trauma from a vascular perspective, this book should make a unique contribution to the understanding of traumatic brain and spinal cord injury.
Blood-brain barrier. --- Central nervous system. --- Nervous system, Central --- Blood-cerebral barrier --- Blood-cerebrospinal fluid barrier --- Brain-blood barrier --- Hemato-encephalic barrier --- Hematoencephalic barrier --- Neurosciences. --- Neurology. --- Neurobiology. --- Nervous system --- Brain --- Cerebrospinal fluid --- Choroid plexus --- Blood-vessels --- Neurosciences --- Medicine --- Neuropsychiatry --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Diseases --- Neurology .
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Drug development. --- Blood-brain barrier --- Effect of drugs on. --- Blood-cerebral barrier --- Blood-cerebrospinal fluid barrier --- Brain-blood barrier --- Hemato-encephalic barrier --- Hematoencephalic barrier --- Brain --- Cerebrospinal fluid --- Choroid plexus --- Development of drugs --- Drugs --- New drug development --- Pharmacology --- Pharmacy --- Blood-vessels --- Development
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Blood-brain barrier --- Nanotechnology. --- Drug development. --- Brain --- Effect of drugs on. --- Cancer --- Treatment. --- Development of drugs --- Drugs --- New drug development --- Pharmacology --- Pharmacy --- Molecular technology --- Nanoscale technology --- High technology --- Blood-cerebral barrier --- Blood-cerebrospinal fluid barrier --- Brain-blood barrier --- Hemato-encephalic barrier --- Hematoencephalic barrier --- Cerebrospinal fluid --- Choroid plexus --- Development --- Blood-vessels
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The molecular basis for the physiology of the brain has advanced enormously in the past twenty years with an influx of new information gleaned through technological developments in neuroimaging and molecular discoveries. Molecular Physiology and Metabolism of the Nervous System, authored by Gary A. Rosenberg, an authority on the physiology of brain fluids and metabolism, combines the classic physiology that dates back to the beginning of the nineteenth century with the advances in molecular sciences, providing a strong framework for understanding the diseases that are commonly treated by neuro
Cerebrospinal fluid --- Blood-brain barrier --- Brain --- Cerebral circulation --- Cerebral blood flow --- Cerebrovascular circulation --- Circulation, Cerebral --- Blood --- Cerebrorachidian fluid --- CSF (Cerebrospinal fluid) --- Body fluids --- Spinal cord --- Cerebrum --- Mind --- Central nervous system --- Head --- Blood-cerebral barrier --- Blood-cerebrospinal fluid barrier --- Brain-blood barrier --- Hemato-encephalic barrier --- Hematoencephalic barrier --- Choroid plexus --- Physiology. --- Pathophysiology. --- Metabolism. --- Circulation --- Blood-vessels
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Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.
Blood-brain barrier. --- Blood-cerebral barrier --- Blood-cerebrospinal fluid barrier --- Brain-blood barrier --- Hemato-encephalic barrier --- Hematoencephalic barrier --- Brain --- Cerebrospinal fluid --- Choroid plexus --- Blood-vessels --- Biochemistry. --- Medicine. --- Toxicology. --- Medicinal Chemistry. --- Molecular Medicine. --- Pharmacology/Toxicology. --- Chemicals --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Toxicology --- Composition --- Health Workforce --- Medicinal chemistry. --- Molecular biology. --- Pharmacology. --- Drug effects --- Medical pharmacology --- Chemotherapy --- Drugs --- Pharmacy --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Physiological effect
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This book was written by many outstanding investigators who have spent decades to study different aspects of blood‑tissue barrier function. They have summarized some of the latest and fascinating development in their fields of research including the blood‑brain barrier, the blood‑retinal barrier, the gut barrier, the blood‑biliary barrier, the blood‑follicle barrier, the blood‑epididymis barrier, the blood‑testis barrier, the tight junction barrier in general as well as barriers in the female reproductive tract. Included are also chapters that focus on topics that are physiologically applicable to all blood‑tissue barriers. Many of these chapters also include information on specific human diseases, such as pathological changes of the gut barrier that cause bowel disorders resulting from inflammation of the epithelial lining in the intestine, and infertility in men as a result of disruption of the blood‑epididymal and/or blood‑testis barriers; and on new therapeutic approaches (e.g., drug delivery across the blood‑brain and the blood‑retinal barriers).
Blood-air barrier. --- Blood-brain barrier. --- Capillaries -- Permeability. --- Capillary permeability. --- Blood-brain barrier --- Capillaries --- Cardiovascular Physiological Phenomena --- Retina --- Seminiferous Tubules --- Pulmonary Alveoli --- Cardiovascular System --- Biological Transport --- Brain --- Anatomy --- Testis --- Central Nervous System --- Lung --- Eye --- Circulatory and Respiratory Physiological Phenomena --- Metabolism --- Respiratory System --- Sense Organs --- Metabolic Phenomena --- Phenomena and Processes --- Nervous System --- Genitalia, Male --- Genitalia --- Urogenital System --- Blood-Air Barrier --- Blood-Brain Barrier --- Blood-Testis Barrier --- Capillary Permeability --- Blood-Retinal Barrier --- Human Anatomy & Physiology --- Health & Biological Sciences --- Neuroscience --- Permeability --- Permeability. --- Blood-cerebral barrier --- Blood-cerebrospinal fluid barrier --- Brain-blood barrier --- Hemato-encephalic barrier --- Hematoencephalic barrier --- Medicine. --- Molecular biology. --- Biomedicine. --- Molecular Medicine. --- Biomedicine general. --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Cerebrospinal fluid --- Choroid plexus --- Blood-vessels --- Biomedicine, general. --- Health Workforce
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