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Clinical trials of medicinal products on human subjects are a balancing act between the protection of the study participant and the preservation of his dignity on the one hand and the constant striving for medical progress on the other hand. This applies likewise to the control group as an essential part of every clinical testing of pharmaceuticals without which no drug will receive marketing authorisation in Germany by the competent authorities. Nevertheless, significant gaps in the German legislation concerning this matter still remain as the German legislator has yet to implement any specific rules with regard to the handling and management of the control group in clinical trials. In view of this unsettled legal situation, the author critically analyses the core of the problem areas in this field's current research practice and creates solutions reflecting the interests of the study participant as well as the practical needs of medical research. Only legal clarity regarding the control group can provide for the safety that is crucial in this field of tension between ethics, medicine and the law.
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The recorded use of deadly force against unarmed suspects and sustained protest from the Black Lives Matter movement, among others, have ignited a national debate about excessive violence in American policing. Missing from the debate, however, is any discussion of a factor that is almost certainly contributing to the violence—the use of anabolic steroids by police officers. Mounting evidence from a wide range of credible sources suggests that many cops are abusing testosterone and its synthetic derivatives. This drug use is illegal and encourages a “steroidal” policing style based on aggressive behaviors and hulking physiques that diminishes public trust in law enforcement. Dopers in Uniform offers the first assessment of the dimensions and consequences of the felony use of anabolic steroids in major urban police departments. Marshalling an array of evidence, John Hoberman refutes the frequent claim that police steroid use is limited to a few “bad apples,” explains how the “Blue Wall of Silence” stymies the collection of data, and introduces readers to the broader marketplace for androgenic drugs. He then turns his attention to the people and organizations at the heart of police culture: the police chiefs who often see scandals involving steroid use as a distraction from dealing with more dramatic forms of misconduct and the police unions that fight against steroid testing by claiming an officer’s “right to privacy” is of greater importance. Hoberman’s findings clearly demonstrate the crucial need to analyze and expose the police steroid culture for the purpose of formulating a public policy to deal with its dysfunctional effects.
Police --- Steroid abuse. --- Drug use --- Drug testing
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The recorded use of deadly force against unarmed suspects and sustained protest from the Black Lives Matter movement, among others, have ignited a national debate about excessive violence in American policing. Missing from the debate, however, is any discussion of a factor that is almost certainly contributing to the violence—the use of anabolic steroids by police officers. Mounting evidence from a wide range of credible sources suggests that many cops are abusing testosterone and its synthetic derivatives. This drug use is illegal and encourages a “steroidal” policing style based on aggressive behaviors and hulking physiques that diminishes public trust in law enforcement. Dopers in Uniform offers the first assessment of the dimensions and consequences of the felony use of anabolic steroids in major urban police departments. Marshalling an array of evidence, John Hoberman refutes the frequent claim that police steroid use is limited to a few “bad apples,” explains how the “Blue Wall of Silence” stymies the collection of data, and introduces readers to the broader marketplace for androgenic drugs. He then turns his attention to the people and organizations at the heart of police culture: the police chiefs who often see scandals involving steroid use as a distraction from dealing with more dramatic forms of misconduct and the police unions that fight against steroid testing by claiming an officer’s “right to privacy” is of greater importance. Hoberman’s findings clearly demonstrate the crucial need to analyze and expose the police steroid culture for the purpose of formulating a public policy to deal with its dysfunctional effects.
Police --- Steroid abuse. --- Drug use --- Drug testing
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This book reveals the disturbing truth about how the escalation of the War on Drugs over the past 30 years has eroded the human and property rights of Americans--while doing little to stop drug trafficking or use.
Drug control --- Drug legalization --- Drug testing --- Social problems
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This book provides an overview and quick reference to genetic relationships and clinical laboratory information related to the serious public health issue of alcohol and drug abuse. It discusses the necessary information for health and safety professionals working in public health to learn about complex issues quickly to better help their patients, employees, and others affected by alcohol and drug abuse.
Drugs of abuse. --- Alcohol. --- Substance abuse --- Alcoholism. --- Alcoholism --- Drinking of alcoholic beverages. --- Drug abuse. --- Drug abuse --- Drug testing. --- Genetic aspects.
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This book ""New Insights into Toxicity and Drug Testing"" covers all emerging technologies (profiling technologies, 3D cultures, next generation sequencing etc.), available methods and models to evaluate candidate drugs and medicinal plants with reference to toxicity, drug testing and development. This book is an original contribution of experts from different parts of the globe and the in-depth information will be a significant resource for scientists and physicians who are directly dealing with drugs / medicines and human life.
Drug testing. --- Drugs --- Toxicology. --- Drug toxicity --- Drug abuse --- Drug abuse screening --- Screening for drug abuse --- Testing for drug abuse --- Medical screening --- Side effects --- Testing --- Toxicology --- Toxicology and Pharmaceutical Science --- Pharmacology --- Medical Toxicology --- Health Sciences
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The main scope of this topic is to give an update on pharmacologic and non-pharmacologic approaches to enhance uptake and penetration of cancer drugs into tumors. Inadequate accumulation of drugs in tumors has emerged over the last decade as one of the main problems underlying therapeutic failure and drug resistance in the treatment of cancer.
Neoplasms. --- Tumors. --- Oncology. --- Cancer --- Drug testing. --- Cancers --- Carcinoma --- Malignancy (Cancer) --- Malignant tumors --- Tumors --- Neoplasms --- Tumours --- Pathology --- Cysts (Pathology) --- Oncology --- Resistance --- microenvironment --- Administration --- targeting --- Penetration --- Drug delivery --- Permeability --- Junctions --- Integrins
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Police --- Cops --- Gendarmes --- Law enforcement officers --- Officers, Law enforcement --- Officers, Police --- Police forces --- Police officers --- Police service --- Policemen --- Policing --- Criminal justice, Administration of --- Criminal justice personnel --- Peace officers --- Public safety --- Security systems --- Drug testing --- Legal status, laws, etc.
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Saliva --- Drug testing. --- Analysis. --- Examination. --- Drug abuse --- Drug abuse screening --- Screening for drug abuse --- Testing for drug abuse --- Medical screening --- Body fluids --- Exocrine glands --- Mouth --- Parotid glands --- Salivary glands --- Drooling --- Sputum --- Testing --- Secretions
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