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Book
Circadian rhythms
Authors: ---
ISBN: 9781614700104 1614700109 9781613248584 161324858X Year: 2012 Publisher: New York


Book
Circadian rhythm : cellular and molecular mechanisms
Authors: ---
ISBN: 1789233399 1789233380 1838816011 Year: 2018 Publisher: IntechOpen

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Circadian clocks are endogenous and temperature-compensating timekeepers that provide temporal organization of biological processes in living organisms. Circadian rhythms allow living organisms to adapt to the daily light cycles associated with Earth's rotation and to anticipate and prepare for precise and regular environmental changes. This book discusses the fundamental advances of how the circadian clock regulates critical biological functions as well as the cellular and molecular mechanisms controlling circadian rhythm in living organisms. It also provides new insights into and sheds new light on the current research trends and future research directions related to circadian rhythm. This book provokes interest in many readers, researchers and scientists, who can find this information useful for the advancement of their research works towards a better understanding of circadian rhythm regulatory mechanisms.


Book
Therapeutic implications of circadian rhythms
Authors: --- --- ---
ISBN: 9782889196654 Year: 2015 Publisher: Frontiers Media SA

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Circadian rhythms are biological processes displaying endogenous and entrainable oscillations of about 24 hours. They are driven by a group of genes called clock genes that have been widely observed in plants, animals and even in bacteria. In mammals, the core clock genes are rhythmically expressed in both the suprachiasmatic nucleus (SCN), the master clock residing in the hypothalamus, and almost all peripheral tissues where they control numerous target genes in a circadian manner, and thus affect many physiological and biochemical processes. Evidence suggests that disruption of the circadian rhythms (or desynchronization) is a significant risk factor for the development of metabolic diseases, cardiovascular diseases, cancer and sleep disorders. Evidence also suggests that the disruption suppresses immune function and increases vulnerability to infectious diseases. Restoring or strengthening the circadian rhythm may be therapeutic for these conditions. This becomes exceptionally important in modern societies because many people are suffering from frequent desynchronization due to shift working, exposure to artificial light, travel by transmeridian air flight, and involvement in social activities. Besides, the temporal variations in the incidence and severity of many diseases, such as the onset of cardiovascular events, chronic obstructive pulmonary disease (COPD), inflammatory diseases and mental disorders have also drawn increasing attention to the circadian clock. The circadian rhythms affect not only the health status, but also the drug efficiency. The effects (and side effects) of many drugs vary with biological timing. The tolerance of many medications displays circadian variation as well. The timing of medical treatment in coordination with the body clock may significantly increase the desired effects of drugs, and lower the dose and toxicity. In addition, circadian rhythms can also be modulated by some therapeutic drugs, for example, melatonin and modafinil, which are used to treat circadian rhythm sleep disorders. In this Research Topic, we assemble a series of critical review and research articles that focus on the therapeutic implications of circadian rhythms.


Book
Biological clocks
Authors: ---
ISBN: 1612098614 9781612098616 1607412519 9781607412519 Year: 2010 Publisher: New York


Book
Circadian rhythms in bacteria and microbiomes
Authors: ---
ISBN: 3030721582 3030721574 Year: 2021 Publisher: Cham, Switzerland : Springer,


Book
Insect Chronobiology
Authors: ---
ISBN: 9819907268 981990725X Year: 2023 Publisher: Singapore : Springer,

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This book reviews the physiological mechanisms of diverse insect clocks, including circadian clock, lunar clock, tidal clock, photoperiodism, circannual rhythms and others. It explains the commonality and diversity of insect clocks, focusing on the recent advances in their molecular and neural mechanisms. In the history of chronobiology, insects provided important examples of diverse clocks. The first report of animal photoperiodism was in an aphid, and the time-compensated celestial navigation was first shown in the honeybee. The circadian clock was first localized in the brain of a cockroach. These diverse insect clocks also have some common features which deserve to be reviewed in a single book. The central molecular mechanism of the circadian clock, i.e., the negative feedback loop of clock genes, was proposed in Drosophila melanogaster in the 1990s and later became the subject of the Nobel Prize in Physiology or Medicine in 2017. Thereafter, researches on the molecular and neural mechanisms in diverse insect clocks other than the Drosophila circadian clock also advanced appreciably. Various new methods including RNAi, NGS, and genome editing with CRISPR-Cas9 have become applicable in these researches. This book comprehensively reviews the physiological mechanisms in diverse insect clocks in the last two decades, which have received less attention than the Drosophila circadian clock. The book is intended for researchers, graduate students, and highly motivated undergraduate students in biological sciences, especially in entomology and chronobiology. .


Book
Cellular Rhythms and Networks : Implications for Systems Medicine
Author:
ISBN: 3319228188 3319228196 Year: 2015 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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This book provides an overview of circadian rhythms and cellular networks in their relation to biological systems and dynamical medicine. Six concise chapters explore circadian cell rhythms and biomarkers in inflammation, cardiovascular disease, cancer, depression, and more in causing and treating these ailments. The final chapter discusses optimization of drug delivery and individualized treatment systems using chronotherapy and chronobiology-based biomarkers as a general system of medicine. Succinct yet comprehensive, Cellular Rhythms and Networks, part of SpringerBriefs in Cell Biology presents a novel framework for clinical applications in personalized and systems medicine. It is invaluable reading for researchers and clinicians in cell biology, mood disorders, and systems medicine.

In sync with adolescence : the role of morningness-eveningness in adolescence
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ISBN: 1280804254 9786610804252 0387238220 0387224173 1489986537 Year: 2005 Publisher: New York : Springer Science,

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At the start of every school day, it’s not an unfamiliar sight to see younger children bounding toward school, bright-eyed and bushy-tailed, ready to seize the day. In contrast, adolescents sometimes seem to sleepwalk toward their middle and high schools, often bleary-eyed, cantankerous, and less than enthusiastic to get down to work. Why the difference? Recent developmental research has demonstrated a relationship between sleep/wake patterns and different kinds of problem behaviors, including social adjustment problems, family coercion, and disaffection from school. Adolescents who prefer staying up later in the evening and arising late in the morning (i.e., eveningness) have often been considered at greater risk of suffering from such problem behaviors as delinquency and negative relationships with parents and teachers. Those who tend to go to bed and arise earlier (i.e., morningness) have long been associated with more positive outcomes. In the majority of previous research, however, these concepts have never been adequately tested. In Sync with Adolescence: The Role of Morningness-Eveningness in Development examines the possible effects of adolescent preferences on problem behavior in different contexts. This volume presents a new way of looking at morningness-eveningness in relation to adolescent development in general and on problem behavior in particular. The study has produced results, the implications of which necessitate a reinterpretation of the current thinking about morningness-eveningness and adolescent adjustment. This volume should be of particular interest to developmental psychologists and researchers who are interested in examining the role of biological factors in psychological processes as well as to sleep researchers who are interested in both the clinical and behavioral aspects. In addition, it is a valuable resource for clinical child and school psychologists, medical staff, teachers, and anyone who works with adolescents.

Blood pressure monitoring in cardiovascular medicine and therapeutics
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ISBN: 1280971622 9786610971626 1592599788 1588295125 Year: 2007 Publisher: Totowa, N.J. : Humana Press,

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In this newly updated second edition of Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics, William B. White, MD, and a panel of highly distinguished clinicians give a critical review of every aspect of the evaluation of high blood pressure. This includes home and ambulatory blood pressure monitoring, the relationship between whole-day blood pressure and the cardiovascular disease process, and the effects of antihypertensive therapies on these blood pressure parameters. World-class contributors describe the significant advances in our understanding of the circadian pathophysiology of cardiovascular disorders and demonstrate that ambulatory blood pressure values are independent predictors of cardiovascular morbidity and mortality. This book provides a comprehensive up-to-date resource of this dynamic field in hypertension and vascular disease.

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