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The World Health Organization's Stop TB Department has prepared this fourth edition of Treatment of Tuberculosis: Guidelines, adhering fully to the new WHO process for evidence-based guidelines. Several important recommendations are being promoted in this new edition. First, the recommendation to discontinue the regimen based on just 2 months of rifampicin (2HRZE/6HE) and change to the regimen based on a full 6 months of rifampicin (2HRZE/4HR) will reduce the number of relapses and failures. This will alleviate patient suffering resulting from a second episode of tuberculosis (TB) and conserve

Antitubercular agents. --- Adherence of patients --- Compliance of patients --- Cooperation of patients --- Patient adherence --- Patient cooperation --- Treatment compliance --- Drugs, Antitubercular --- Tuberculostatic agents --- Compliance with regimen --- Tuberculosis --- Patient compliance. --- Sick --- Compliance --- Health behavior --- Medical cooperation --- Therapist and patient --- Antibacterial agents --- Antitubercular agents --- Chemotherapy. --- Cooperation --- Chemotherapy

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An estimated 2 billion people, one third of the global population, are infected with Mycobacterium tuberculosis, the bacterium that causes tuberculosis. Spread through the air, this infectious disease killed 1.7 million in 2009, and is the leading killer of people with HIV. Tuberculosis (TB) is also a disease of poverty--the vast majority of tuberculosis deaths occur in the developing world. Exacerbating the devastation caused by TB is the growing threat of drug-resistant forms of the disease in many parts of the world. Drug-resistant tuberculosis presents a number of significant challenges in terms of controlling its spread, diagnosing patients quickly and accurately, and using drugs to treat patients effectively. In Russia in recent decades, the rise of these strains of TB, resistant to standard antibiotic treatment, has been exacerbated by the occurrence of social, political, and economic upheavals. The Institute of Medicine (IOM) Forum on Drug Discovery, Development, and Translation, in conjunction with the Russian Academy of Medical Sciences held a workshop to discuss ways to fight the growing threat of drug-resistant TB. This book presents information from experts on the nature of this threat and how it can be addressed by exploring various treatment and diagnostic options.

Multidrug-resistant tuberculosis - Russia. --- Multidrug-resistant tuberculosis --- Mycobacterium tuberculosis --- Antitubercular agents --- Anti-Bacterial Agents --- Mycobacterium Infections --- Actinomycetales Infections --- Anti-Infective Agents --- Therapeutic Uses --- Gram-Positive Bacterial Infections --- Pharmacologic Actions --- Bacterial Infections --- Bacterial Infections and Mycoses --- Chemical Actions and Uses --- Diseases --- Chemicals and Drugs --- Tuberculosis, Multidrug-Resistant --- Tuberculosis --- Antitubercular Agents --- Public Health --- Health & Biological Sciences --- Communicable Diseases --- Consumption (Disease) --- Lungs --- Phthisis --- Pulmonary tuberculosis --- TB (Disease) --- Chest --- Mycobacterial diseases

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"Tuberculosis is one of the leading causes of death in the world today, with 4,500 people dying from the disease every day. Many cases of TB can be cured by available antibiotics, but some TB is resistant to multiple drugs--a major and growing threat worldwide. The Institute of Medicine's Forum on Drug Discovery, Development, and Translation hosted a workshop on November 5, 2008, to address the mounting concern of drug-resistant TB. The session brought together a wide range of international experts to discuss what is known and not known about this growing threat, and to explore possible solutions."--Publisher's website.

Antitubercular agents -- Congresses. --- Drug resistance -- Congresses. --- Electronic books. -- local. --- Multidrug-resistant tuberculosis -- Congresses. --- Tuberculosis -- Congresses. --- Multidrug-resistant tuberculosis --- Tuberculosis --- Drug resistance --- Antitubercular agents --- Congresses --- Internationality --- HIV Infections --- Tuberculosis, Multidrug-Resistant --- Antitubercular Agents --- Anti-Bacterial Agents --- Publication Formats --- Sexually Transmitted Diseases, Viral --- Lentivirus Infections --- Social Sciences --- Immunologic Deficiency Syndromes --- Retroviridae Infections --- Mycobacterium Infections --- Publication Characteristics --- Anti-Infective Agents --- Immune System Diseases --- Anthropology, Education, Sociology and Social Phenomena --- Sexually Transmitted Diseases --- Virus Diseases --- Actinomycetales Infections --- RNA Virus Infections --- Diseases --- Therapeutic Uses --- Gram-Positive Bacterial Infections --- Pharmacologic Actions --- Chemical Actions and Uses --- Bacterial Infections --- Bacterial Infections and Mycoses --- Chemicals and Drugs --- Infectious Diseases --- Medicine --- Health & Biological Sciences --- Drugs, Antitubercular --- Tuberculostatic agents --- Resistance to drugs --- MDR-TB (Multidrug-resistant tuberculosis) --- MDR tuberculosis --- Polydrug-resistant tuberculosis --- Antibacterial agents --- Pharmacology --- Drug resistance in microorganisms --- Multidrug resistance --- Chemotherapy

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Tuberculosis --- Tuberculose --- Periodicals. --- Périodiques --- Tuberculosis. --- tuberculosis --- mycobacterium tuberculosis --- Consumption (Disease) --- Lungs --- Phthisis --- Pulmonary tuberculosis --- TB (Disease) --- Chest --- Mycobacterial diseases --- Mycobacterium tuberculosis --- Koch's Disease --- Kochs Disease --- Mycobacterium tuberculosis Infection --- Infection, Mycobacterium tuberculosis --- Infections, Mycobacterium tuberculosis --- Koch Disease --- Mycobacterium tuberculosis Infections --- Tuberculoses --- Antitubercular Agents --- Tuberculin Test --- Interferon-gamma Release Tests --- Diseases --- Human medicine --- Infectious Diseases

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Tuberculosis --- Nanomedicine. --- Tuberculosis. --- therapy. --- Nanomedicine --- Treatment. --- methods. --- Koch's Disease --- Kochs Disease --- Mycobacterium tuberculosis Infection --- Infection, Mycobacterium tuberculosis --- Infections, Mycobacterium tuberculosis --- Koch Disease --- Mycobacterium tuberculosis Infections --- Tuberculoses --- Antitubercular Agents --- Tuberculin Test --- Interferon-gamma Release Tests --- Medicine --- Nanotechnology --- Consumption (Disease) --- Lungs --- Phthisis --- Pulmonary tuberculosis --- TB (Disease) --- Chest --- Mycobacterial diseases --- Mycobacterium tuberculosis --- Diseases